Hepatic abscess: a rare complication after liver transplant

Abstract

Hepatic abscess after liver transplantation may be treated successfully with percutaneous and endoscopic intervention, along with antibiotics according to the results of microbial cultures of blood and/or abscess aspirates.

Pyogenic liver abscess in liver transplant recipient: A warning signal for the risk of recurrence and retransplantation

“…When comparing our data to other published series of PLA-LTR, we observed a longer time from liver transplantation to PLA diagnosis than previously reported. [16][17][18][19][20][21][22] Of note, Justo et al, in a recent Spanish series, also observed a long median interval of 39.7 months from liver transplantation, which contrasted with the shorter duration (2-13 months) reported previously by most authors. [16][17][18][19]22 The majority of PLA-LTR were caused by ischemic cholangitis due to hepatic arterial thrombosis (HAT-IC), which occurred later in our case series (8/10 late HAT) than in most of the others.…”

“…[16][17][18][19][20][21][22] Of note, Justo et al, in a recent Spanish series, also observed a long median interval of 39.7 months from liver transplantation, which contrasted with the shorter duration (2-13 months) reported previously by most authors. [16][17][18][19]22 The majority of PLA-LTR were caused by ischemic cholangitis due to hepatic arterial thrombosis (HAT-IC), which occurred later in our case series (8/10 late HAT) than in most of the others. [16][17][18][19]22 Early HAT (within 30 days after liver transplantation) is more frequently related to technical problems (complex hepatic artery anatomy, hepatic artery dissection, atheroma, etc).…”

“…and with 1-year mortality rates ranging from 12% to 21% of patients. [16][17][18][19][20][21][22] Risk factors associated with PLA-LTR include a history of hepatic artery thrombosis, biliary stricture, the presence of Roux-en-Y hepaticojejunostomy, cholangitis, live donor transplantation, split liver, donation after cardiac death, prolonged ischemia time, liver biopsy, and diabetes. 21,22 However, many questions remain unanswered including clinical and radiological characteristics, the microbial epidemiology, optimal management, and outcome of PLA-LTR.…”

“…21,22 However, many questions remain unanswered including clinical and radiological characteristics, the microbial epidemiology, optimal management, and outcome of PLA-LTR. [16][17][18][19][20] We conducted a large monocentric case-control study in which aim was to better characterize specificities of PLA-LTR as compared to PLA occurring in patients with native livers.…”

Liver fungal infections: an overview of the etiology and epidemiology in patients affected or not affected by oncohematologic malignancies

“…Although bacteria represent the most common causative agents, fungi cannot be neglected in the differential diagnosis, considering their impact, in terms of morbidity and mortality, in the setting of posttransplantation infections. 81 Indeed, in the light of the recommendations from the most authoritative international societies, antifungal prophylaxis following OLT, to prevent IFIs, is not mandatory for low-risk patients, but it is necessary under several circumstances: 1) only against Candida spp. for patients with perioperative Candida colonization complicated operations or choledochojejunostomy anastomosis and 2) against both Candida and Aspergillus for patients at high risk, undergoing renal replacement therapy posttransplant and with the high probability of reoperation.…”