Hemolytic uremic syndrome and diarrhea associated with Escherichia coli 0157:H7 in a day care center

SUMMARYA point source outbreak of haemorrhagic colitis due to Escherichia coli 0 157. 117 producing verocytotoxin (VT), took place following a christening party in Birmingham in June 1987. Twenty-six people were affected, six were admitted to hospital and one developed haemolytic uraemic syndrome: there were no deaths. VT + E. coli 0 157. H7 was isolated from 13 (57 %) of 23 faecal specimens from affected people and from 3 (90%)) of 33 specimens from asymptomatic people.Free VT was detected in the faeces of one further asymptomatic person. Illness was associated with eating turkey-roll sandwiches (P < 0.00 1) suggesting that cold meats might be an important source of infection.

Section: Discussionmentioning

confidence: 86%

“…Subsequently, outbreaks and sporadic cases have been reported from North America (2-7) and Japan (8). Some cases have developed haemolytic uraemic syndrome (HUS) (3)(4)(5)9). In England and Wales sporadic cases of HUS (10) and HC (8) and one outbreak of HC in East Anglia in 1985 (11) (12,13).…”

mentioning

confidence: 99%

A christening party outbreak of haemorrhagic colitis and haemolytic uraemic syndrome associated with Escherichia coli O 157. H7

Salmon

Farrell²,

Hutchison³

et al. 1989

“…Following the discovery that the causative agent was E. coli 0 157 . H7-producing verotoxin a wider spectrum of illness has been revealed, which ranges from asymptomatic carriage through non-bloody diarrhoea to haemorrhagic colitis and haemolytic uraemic syndrome (Ryan et al 1986;Spika et al 1986). In the outbreak in East Anglia the spectrum of cases identified was limited 88 by the use of a strict case definition for haemorrhagic colitis, but two infected patients who did not have bloody diarrhoea were identified.…”

Section: Discussionmentioning

confidence: 99%

“…H7 has been identified recently as the causal agent of outbreaks (Riley et al 1983;Pudden et al 1985;Ryan et al 1986;Spika et al 1986) and sporadic cases (Remis et al 1984;Pai et al 1984) of haemorrhagic colitis in North America, and as one of the causes of the haemolytic uraemic syndrome (HUS) (Karmali et al 1985). In England and Wales this organism has been isolated from 39% of sporadic cases of haemorrhagic colitis ) and 33 % of sporadic cases of HUS (Scotland et al 1988) and from cases in an outbreak of HUS in the West Midlands (Taylor et al 1986).…”

Section: Introductionmentioning

confidence: 99%

First recognized community outbreak of haemorrhagic colitis due to verotoxin-producingEscherichia coliO 157.H7 in the UK

Morgan¹,

Newman²,

Palmer³

et al. 1988

104

SUMMARYThe first recognized outbreak of haemorrhagic colitis due to Escherichia coli O 157. H7 in the United Kingdom affected at least 24 persons living in East Anglia over a 2-week period. The illnesses were characterized by severe abdominal pain and bloody diarrhoea of short duration. Eleven patients were admitted to hospital and there was one death. Patients were mainly adult women who had not eaten out of the home in the 2 weeks before onset. Unlike previously reported outbreaks hamburgers were not the vehicle of infection, and a case-control study suggested that handling vegetables, and particularly potatoes, was the important risk factor.

“…H7, have become increasingly recognized internationally since the early 1980s. The bovine source of infection has been frequently identified and outbreaks involving foodborne [1][2][3][4], waterborne [5,6] and person-to-person [7,8] transmission have been reported including several affecting children's day-care facilities [4,7,9].…”

Section: Introductionmentioning

confidence: 99%

An outbreak ofEscherichia coliO157 associated with a children's paddling pool

Brewster

Brown

Robertson³

et al. 1994

SUMMARYIn May 1992, a small, circumscribed community outbreak of infection due to verotoxin-producing Escherichia coli 0157 phage type 49 occurred in a semi-rural area of south-east Scotland. On the basis of stool cultures, six cases were identified, one of whom was asymptomatic. One child developed the haemolytic uraemic syndrome. Although the source of infection of the index case was not established nor could the extent of person-to-person spread be fully determined, the clinical, microbiological and epidemiological evidence available indicated that a children's paddling pool served as the focal point in the transmission of infection causing the outbreak.