Hemolysis in fresh human blood with a new hemoperfusion pump to prevent myocardial ischemia during coronary angioplasty

Demuinck, Ed; Meeder, JG; Magielse, Cpe; Bom, Vjj; Verkerke, Gijsbertus Jacob; Lie, Ki

doi:10.3233/thc-1993-1207

Cited by 3 publications

(1 citation statement)

References 9 publications

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“…Many modified procedures to overcome these complications of PTCA have been proposed. So far none of these seem to decrease the restenosis rate significantly [11][12][13][14]. Many other procedures for recanalization have been proposed as well-atherectomy [15,16], laser angioplasty [17], stenting [18], and rotablator [19].…”

Section: Introductionmentioning

confidence: 99%

Rupture of the arterial wall causes deflection in pressure time course during ex vivo balloon angioplasty

Steenhuijsen¹,

Vaartjes²,

Poortermans³

et al. 1997

Cathet. Cardiovasc. Diagn.

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A relation between restenosis and arterial lesions resulting from balloon angioplasty has been suggested in literature. Nevertheless, it is unclear to what extent angioplastyinduced arterial wall lesions contribute to the occurrence of restenosis. One problem is that arterial ruptures cannot be detected during balloon inflation. This study describes a method to detect ruptures in the arterial wall, based on deflections observable in the development of the balloonpressure. We performed ex vivo angioplasty with constant strain rate on 28 human femoral artery segments, showing deflections in 21 cases. In 20 cases wall rupture was confirmed histologically. From seven cases not showing deflections, four showed intact wall at microscopy. These figures result in a selectivity of the proposed method of 87 6 7% and a predictive value of the positive test of 95 6 5%. We conclude that this method can enhance detection of arterial rupture during ex vivo angioplasty and may become important clinically. Cathet. Cardiovasc. Diagn. 42:92-101, 1997. r 1997 Wiley-Liss, Inc.

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Section: Introductionmentioning

confidence: 99%

Rupture of the arterial wall causes deflection in pressure time course during ex vivo balloon angioplasty

Steenhuijsen¹,

Vaartjes²,

Poortermans³

et al. 1997

Cathet. Cardiovasc. Diagn.

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Distal coronary hemoperfusion during percutaneous transluminal coronary angioplasty

Muinck

1996

Cathet. Cardiovasc. Diagn.

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Regional Flow Adjusted Hemoperfusion During Coronary Angioplasty: Circulatory Support/Myocardial Protection

Overlie

1995

J Interven Cardiology

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Routine percutaneous transluminal coronary angioplasty catheters are adequate and demonstrate high success rates in balloon angioplasty with stable patients. Active hemoperfusion seems to offer an advantage in patients with hemodynamic instability. Active hemoperfusion provides myocardial protection during coronary interventions and can be applied in conjunction with routine angioplasty equipment. When compared with other devices demonstrating clinical utility in a supported angioplasty setting, this flow adjustable active antegrade hemoperfusion pump appears reliable, simple to use, cost-effective, and requires much less instrumentation than the more bulky CPS systems.

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Hemolysis in fresh human blood with a new hemoperfusion pump to prevent myocardial ischemia during coronary angioplasty

Cited by 3 publications

References 9 publications

Rupture of the arterial wall causes deflection in pressure time course during ex vivo balloon angioplasty

Rupture of the arterial wall causes deflection in pressure time course during ex vivo balloon angioplasty

Distal coronary hemoperfusion during percutaneous transluminal coronary angioplasty

Regional Flow Adjusted Hemoperfusion During Coronary Angioplasty: Circulatory Support/Myocardial Protection

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