Distal coronary hemoperfusion during percutaneous transluminal coronary angioplasty

Muinck, Ebo D. de

doi:10.1002/(sici)1097-0304(199603)37:3<233::aid-ccd1>3.0.co;2-d

Cathet. Cardiovasc. Diagn.

1996

DOI: 10.1002/(sici)1097-0304(199603)37:3<233::aid-ccd1>3.0.co;2-d

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Distal coronary hemoperfusion during percutaneous transluminal coronary angioplasty

Ebo D. de Muinck

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Cited by 4 publications

References 53 publications

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Retroinfusion‐supported stenting in high‐risk patients for percutaneous intervention and bypass surgery: Results of the prospective randomized myoprotect I study

Pohl¹,

Giehrl²,

Reichart³

et al. 2004

Cathet Cardio Intervent

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The objective of this study was to assess event-free survival and total treatment costs of retroinfusion-supported stenting in high-risk patients compared to bypass surgery. An increasing number of patients with main-stem and main-stem-equivalent stenosis are treated by stent implantation, which appears to be safe in the short-term follow-up. However, there is a lack of randomized studies comparing conventional bypass surgery with stent implantation, particularly in patients with high risk for both treatments. We here report on the 1-year results of a prospective randomized single-center study in patients with symptomatic main-stem and main-stem-equivalent lesions with substantially increased risk for bypass surgery. Patients where randomized to undergo either percutaneous transluminal coronary angioplasty/stent procedure (n = 23) or bypass surgery (n = 21). Patients randomized to stent implantation were supported by selective pressure-regulated retroinfusion of the anterior cardiac vein during ischemia. Patients of the stent group and the bypass group did not differ in baseline characteristics, including Parsonnet score and quality-of-life score. Twenty-eight-day mortality and 1-year mortality rate as well as quality-of-life scores were similar in both groups. Event-free survival after 1 year was higher in the bypass group (71.4% vs. 52.3%; P = 0.02) due to a lower target lesion revascularization rate. With regard to total treatment costs, however, the stent group compared favorably to the bypass group (9,346 +/- 807 vs. 26,874 +/- 3,985 euro), predominantly as a result of a shorter intensive care and hospital stay. In this first randomized study in high-risk patients for stent implantation and bypass surgery, patients with retroinfusion-supported stent implantation had a similar 1-year outcome and quality of life compared to patients with bypass surgery. Though in the stent group event-free survival was lower and target lesion revascularization rate was higher, retroinfusion-supported stent implantation was associated with substantially lower costs and might be considered as an alternative treatment option in this selected group of high-risk patients.

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Retroinfusion‐supported stenting in high‐risk patients for percutaneous intervention and bypass surgery: Results of the prospective randomized myoprotect I study

Pohl¹,

Giehrl²,

Reichart³

et al. 2004

Cathet Cardio Intervent

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A Coronary Active Perfusion System for Off-Pump Coronary Artery Bypass: Advantage over Passive Perfusion Regarding the Physiology of the Coronary Artery

Kamiya

Watanabe²,

Doi³

et al. 2002

ASAIO Journal

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To avoid myocardial ischemia during off-pump coronary artery bypass, we developed a coronary active perfusion system (CAPS) that perfuses arterial blood to the coronary artery at the diastolic phase of the cardiac cycle by a syringe pump system. We report herein the details and compare CAPS with a passive shunt circuit from the femoral artery (FA shunt), regarding the physiology of the coronary artery. Six pigs were used for this study. After CAPS or FA shunt perfusion was established, coronary flow and coronary pressure were measured. The coronary flows in the native coronary artery, FA shunt perfusion, and CAPS perfusion with syringe pump stroke volume settings ranging from 0.1 to 0.4 ml were 27.2+/-3.0, 4.1+/-1.5, 12.7+/-1.2, 24.8+/-1.9, 33.3+/-1.6, and 42.2+/-1.9 ml/min, respectively. Mean coronary pressures under FA shunt perfusion and CAPS perfusion with stroke settings from 0.1 to 0.4 ml were 23.7+/-4.6, 48.8+/-5.0, 61.3+/-7.5, 70.8+/-5.4, and 82.3+/-5.2 mm Hg, respectively. CAPS had an advantage over the FA shunt regarding coronary flow with safe coronary pressure. Using CAPS, an off-pump coronary artery bypass can be performed safely without myocardial ischemia.

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Economic and Ethical Issues of Interventional Cardiology in The Netherlands: It Is Time for Managed Care

Jessurun

Heijer

Tio

et al. 1997

J Interven Cardiology

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Distal coronary hemoperfusion during percutaneous transluminal coronary angioplasty

Cited by 4 publications

References 53 publications

Retroinfusion‐supported stenting in high‐risk patients for percutaneous intervention and bypass surgery: Results of the prospective randomized myoprotect I study

Retroinfusion‐supported stenting in high‐risk patients for percutaneous intervention and bypass surgery: Results of the prospective randomized myoprotect I study

A Coronary Active Perfusion System for Off-Pump Coronary Artery Bypass: Advantage over Passive Perfusion Regarding the Physiology of the Coronary Artery

Economic and Ethical Issues of Interventional Cardiology in The Netherlands: It Is Time for Managed Care

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