2005
DOI: 10.1590/s0102-311x2005000100032
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Hemoglobinopathies in newborns from Salvador, Bahia, Northeast Brazil

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Cited by 62 publications
(57 citation statements)
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“…27 This result is similar to those found in the states of São Paulo (23.7%), 28 Bahia (29.1%) and Pernambuco (25.6%). 10,29 In the current study, 21.31% of the patients with Hb S also inherited the α-thal gene and therefore the frequency of α-thal in the Brazilian population is relatively high, with even higher prevalence among Afro-descendants. 20,24,27 Hb S is considered to be the most prevalent hereditary redblood cell disorder in the world.…”
Section: Discussionmentioning
confidence: 50%
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“…27 This result is similar to those found in the states of São Paulo (23.7%), 28 Bahia (29.1%) and Pernambuco (25.6%). 10,29 In the current study, 21.31% of the patients with Hb S also inherited the α-thal gene and therefore the frequency of α-thal in the Brazilian population is relatively high, with even higher prevalence among Afro-descendants. 20,24,27 Hb S is considered to be the most prevalent hereditary redblood cell disorder in the world.…”
Section: Discussionmentioning
confidence: 50%
“…These frequencies vary widely according to the degree of racial admixture in the different regions of Brazil. 10 Since the data from the municipal Health Department of Uberaba show that the prevalence of sickle cell disease in the region in 2012 was 1:1166, the high rate observed in the current study may be due to the small sample size and also to the fact that one of the infants with Hb SS was from a neighboring town (Delta). This child's parents were from northeastern Brazil, and were Afro-descendants who had migrated to work in the sugar cane plantations of the region.…”
Section: Discussionmentioning
confidence: 60%
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“…2,3 Estudo realizado em Salvador, Bahia, através da análise do sangue do cordão umbilical de 590 recém-nascidos, observou a presença de talassemia alfa em 114 recém-nascidos (22,2%; todos com a deleção -α 3,7 ), dos quais 101 (19,7%) eram heterozigotos e 13 (2,5%) homozigotos. 4 Tomé-Alves et al, analisando a presença concomitante de talassemia alfa em pacientes brasileiros portadores de hemoglobina S em heterozigose (Hb AS) com anemia, observaram que das 1.002 amostras de sangue analisadas, 16 (1,59%) pacientes apresentavam a interação Hb AS/talassemia alfa. 5 Couto et al, estudando a associação de talassemia (deleção -α 3,7 ) em indivíduos portadores de hemoglobinopatia C, observaram freqüência de talassemia alfa de 21,7% na forma heterozigótica e de 0,9% na forma homozigótica.…”
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