Hemoglobin detection in blood samples using a graphene-based surface plasmon resonance biosensor

Karki, Bhishma; Vasudevan, B.; Uniyal, Arun; Pal, Amrindra; Srivastava, Vivek

doi:10.1016/j.ijleo.2022.169947

Cited by 65 publications

(12 citation statements)

References 48 publications

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“…Its expression is as follows: Q or FOM = S * DA, expressed in (1/RIU). The desired values for S, DA, and Q should be large, and for FWHM, it should be low [46].…”

Section: Numerical Modelingmentioning

confidence: 99%

Black Phosphorous and Cytop Nanofilm‐Based Long‐Range SPR Sensor with Enhanced Quality Factor

Karki

Uniyal²,

Srivastava

et al. 2023

Journal of Sensors

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This numerical work proposes two novel designs of long-range surface plasmon resonance sensors (LRSPR) using two different coupling prisms. The performance analysis of the proposed sensor has been investigated using the performance parameters like quality factor ( Q ), detection accuracy (DA), sensitivity ( S ), and full-width half maximum (FWHM). The transfer matrix method (TMM) has been employed to compute reflectance. The role of the basic recognition element (BRE) has been played by the popular two-dimensional (2D) material, black phosphorus (BP), due to its many optoelectrical features. The maximum obtained values for Q , DA, and S are 3333.25 1 / RIU , 250 degree − 1 , and 13.33333 degree/RIU for 2S2G coupled sensor design and 3055.5 1 / RIU , 83.33 degree − 1 , and 36.66667 degree/RIU for BK7 coupled sensor design. The operating wavelength of 633 nm, followed by the principle of attenuated total reflection (ATR), has been employed to carry out the theoretical investigation.

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“…Its expression is as follows: Q or FOM = S * DA, expressed in (1/RIU). The desired values for S, DA, and Q should be large, and for FWHM, it should be low [46].…”

Section: Numerical Modelingmentioning

confidence: 99%

Black Phosphorous and Cytop Nanofilm‐Based Long‐Range SPR Sensor with Enhanced Quality Factor

Karki

Uniyal²,

Srivastava

et al. 2023

Journal of Sensors

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“…Full width at half maximum (FWHM) refers to the angular difference corresponding to the half depth of the reflective spectrum, that is [ 37 ]

FWHM = θ_{2} ‐ θ_{1}

Here θ 1 and θ 2 are the incident angles corresponding to 50% reflectivity on the reflection spectrum. Figure of merit (FoM) is correlated with sensitivity and FWHM.…”

Section: Spr Sensor Structure and Modelmentioning

confidence: 99%

“…SPR sensor performance is mainly evaluated by the following parameters. The sensitivity depends on the change in sensing medium (Δn s ) and the resonance angle shift (Δθ), which is expressed by [15] S ¼ Δθ Δn s (8) Full width at half maximum (FWHM) refers to the angular difference corresponding to the half depth of the reflective spectrum, that is [37] FWHM ¼ θ 2 À θ 1 (9) Here θ 1 and θ 2 are the incident angles corresponding to 50% reflectivity on the reflection spectrum. Figure of merit (FoM) is correlated with sensitivity and FWHM.…”

Section: Performance Parametersmentioning

confidence: 99%

Numerical Analysis of Black Phosphorus‐Assisted Copper‐Based Bimetallic‐Enhanced Surface Plasmon Resonance Biosensor

Guo

Chen

et al. 2023

Physica Status Solidi (a)

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Atomically thin black phosphorus (BP) is an emerging 2D material with excellent optical and electrical properties. Copper (Cu) and platinum (Pt) are plasmonic metals due to their outstanding electrical properties. Here, Cu–Pt as the plasmonic bimetal is used, BP as the sensing substrate combined with a composite layer of titanium dioxide–silicon dioxide (TiO2–SiO2) to achieve significant enhancement in sensitivity. All of the calculations are based on the transfer matrix method and Fresnel equations. Through systematic optimization of all parameters, the configuration of TiO2(15 nm)/SiO2 (5 nm)/Cu (26 nm)/Pt (9 nm)/BP (4 layers) is achieved, where the sensitivity of 533° RIU−1 reaches 390% of pure copper‐based biosensor. There is a linear range of sensitivity with the change of refractive index for this optimal configuration. The detection limit of the refractive index change can be as low as 2 × 10−7 RIU, two orders of magnitude lower compared with that of pure copper‐based sensors, indicating great potential to detect trace biomolecules.

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“…They make such structures promising candidates for the components in future nanoelectronics. Graphene/nanodiamond-based heterostructures, superlattices, nanomeshes, and composites are a basis for construction of the novel materials and applications [ 21 , 22 , 23 , 24 ]. Such structures make it possible to control the structural properties, the energy gap, and often to give the material new properties that cannot be obtained by any other means.…”

Section: Introductionmentioning

confidence: 99%

Visualization of Swift Ion Tracks in Suspended Local Diamondized Few-Layer Graphene

et al. 2023

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In the present study we investigated the nanostructuring processes in locally suspended few-layer graphene (FLG) films by irradiation with high energy ions (Xe, 26–167 MeV). For such an energy range, the main channel of energy transfer to FLG is local, short-term excitation of the electronic subsystem. The irradiation doses used in this study are 1 × 1011–5 × 1012 ion/cm2. The structural transformations in the films were identified by Raman spectroscopy and transmission electron microscopy. Two types of nanostructures formed in the FLG films as a result of irradiation were revealed. At low irradiation doses the nanostructures were formed preferably at a certain distance from the ion track and had the form of 15–35 nm “bunches”. We assumed that the internal mechanical stress that arises due to the excited atoms ejection from the central track part creates conditions for the nanodiamond formation near the track periphery. Depending on the energy of the irradiating ions, the local restructuring of films at the periphery of the ion tracks can lead either to the formation of nanodiamonds (ND) or to the formation of AA’ (or ABC) stacking. The compressive strain value and pressure at the periphery of the ion track were estimated as ~0.15–0.22% and ~0.8–1.2 GPa, respectively. The main novel results are the first visualization of ion tracks in graphene in the form of diamond or diamond-like rings, the determination of the main condition for the diamond formation (the absence of a substrate in combination with high ion energy), and estimates of the local strain at the track periphery. Generally, we have developed a novel material and have found how to control the film properties by introducing regions similar to quantum dots with the diamond interface in FLG films.

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Hemoglobin detection in blood samples using a graphene-based surface plasmon resonance biosensor

Cited by 65 publications

References 48 publications

Black Phosphorous and Cytop Nanofilm‐Based Long‐Range SPR Sensor with Enhanced Quality Factor

Black Phosphorous and Cytop Nanofilm‐Based Long‐Range SPR Sensor with Enhanced Quality Factor

Numerical Analysis of Black Phosphorus‐Assisted Copper‐Based Bimetallic‐Enhanced Surface Plasmon Resonance Biosensor

Visualization of Swift Ion Tracks in Suspended Local Diamondized Few-Layer Graphene

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