Hemofiltration in septic ards. the artificial kidney as, an artificial endocrine lung

Clinical Impact of Continuous Renal Replacement Therapy on Multiple Organ Failure

“…This rate is significantly less than that of the 43 studies where patients with MOF and ARF were managed with CRRT (62.8%) (p Ͻ 0.0001). The mortality rate for the studies of ARDS patients was 40.0% (28/70) [15,88,89,91,92]. This rate is not dissimilar from that cited in the contemporary literature [101,102].…”

Clinical Impact of Continuous Renal Replacement Therapy on Multiple Organ Failure

“…This rate is significantly less than that of the 43 studies where patients with MOF and ARF were managed with CRRT (62.8%) (p Ͻ 0.0001). The mortality rate for the studies of ARDS patients was 40.0% (28/70) [15,88,89,91,92]. This rate is not dissimilar from that cited in the contemporary literature [101,102].…”

Hemofiltration in Multiorgan Failure Syndrome Secondary to Sepsis: A Critical Analysis of Heterogeneity

“…(At the present time we are using a more biocom patible low-flux polysulfone.) In this setting, sieving coef ficients for most mediators ranged between 0.89 and 0.94. and were not significantly different from that estimated for urea [40], Even C5a, consistently present in plasma of patients with adult respiratory distress syndrome [41], showing a molecular weight of 11,200, is well within the Gauss curve centered at 10,000 D and. consequently, can also be ultrafiltered with the same membrane.…”

High volume hemofiltration improves right ventricular function in endotoxin-induced shock in the pig

“…Moreover, the authors emphasize the analogy between the mierovascular changes, seen in the heart and in all other organs studied [26,27]. These changes were suggested to be the effect of liberation of vasoactive mediators during sepsis, that potentionally could be removed by hemofiltration [12,26,27].…”

Clinical Impact of Continuous Renal Replacement Therapy on Multiple Organ Failure

“…This rate is significantly less than that of the 43 studies where patients with MOF and ARF were managed with CRRT (62.8%) (p Ͻ 0.0001). The mortality rate for the studies of ARDS patients was 40.0% (28/70) [15,88,89,91,92]. This rate is not dissimilar from that cited in the contemporary literature [101,102].…”

Hemofiltration in Multiorgan Failure Syndrome Secondary to Sepsis: A Critical Analysis of Heterogeneity

“…(At the present time we are using a more biocom patible low-flux polysulfone.) In this setting, sieving coef ficients for most mediators ranged between 0.89 and 0.94. and were not significantly different from that estimated for urea [40], Even C5a, consistently present in plasma of patients with adult respiratory distress syndrome [41], showing a molecular weight of 11,200, is well within the Gauss curve centered at 10,000 D and. consequently, can also be ultrafiltered with the same membrane.…”

High volume hemofiltration improves right ventricular function in endotoxin-induced shock in the pig

“…Moreover, the authors emphasize the analogy between the mierovascular changes, seen in the heart and in all other organs studied [26,27]. These changes were suggested to be the effect of liberation of vasoactive mediators during sepsis, that potentionally could be removed by hemofiltration [12,26,27].…”

Clinical Impact of Continuous Renal Replacement Therapy on Multiple Organ Failure

“…This rate is significantly less than that of the 43 studies where patients with MOF and ARF were managed with CRRT (62.8%) (p Ͻ 0.0001). The mortality rate for the studies of ARDS patients was 40.0% (28/70) [15,88,89,91,92]. This rate is not dissimilar from that cited in the contemporary literature [101,102].…”

Hemofiltration in Multiorgan Failure Syndrome Secondary to Sepsis: A Critical Analysis of Heterogeneity

“…(At the present time we are using a more biocom patible low-flux polysulfone.) In this setting, sieving coef ficients for most mediators ranged between 0.89 and 0.94. and were not significantly different from that estimated for urea [40], Even C5a, consistently present in plasma of patients with adult respiratory distress syndrome [41], showing a molecular weight of 11,200, is well within the Gauss curve centered at 10,000 D and. consequently, can also be ultrafiltered with the same membrane.…”

High volume hemofiltration improves right ventricular function in endotoxin-induced shock in the pig

“…Moreover, the authors emphasize the analogy between the mierovascular changes, seen in the heart and in all other organs studied [26,27]. These changes were suggested to be the effect of liberation of vasoactive mediators during sepsis, that potentionally could be removed by hemofiltration [12,26,27].…”