“…They excluded those which did not have apical pacing for comparison [28,29,52], those utilizing epicardial rather than endocardial leads [38,47,53] and studies performed in heart failure patients [39,45,48], leaving only nine studies eligible for inclusion [33,34,36,37,40,44,46,49,50]. Analysis of the pooled data demonstrated a modest effect on cardiac haemodynamics in favour of RVOT pacing (odds ratio 0.34, CI 0.15-0.53) with only three of these studies being individually positive [44,49,50] and, in two, the initial pacing site was not randomized [49,50].…”