2021
DOI: 10.18203/2320-6012.ijrms20211339
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Hemodialysis duration and underweight as a risk factors of renal osteodystrophy (chronic kidney disease - mineral bone disorder) on regular hemodialysis patient

Abstract: Background: Chronic kidney disease (CKD) is related to systemic disorders affecting multiple organs, including the bone, known as osteoporosis or renal osteodystrophy. Long duration of hemodialysis and underweight based on the Body Mass Index (BMI) is thought to be risk factors for renal osteodystrophy. This study aims to determine the risk factors in the form of hemodialysis duration and underweight in the incidence of renal osteodystrophy in patients with CKD stage 5.Methods: This research is an analytic obs… Show more

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Cited by 2 publications
(2 citation statements)
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“…[ 5 , 9 ] Obese patients had better T-score at FN compared with normal weight individuals, which was consistent with previous findings. [ 13 , 14 ] A third of the study participants with a history of fracture took steroids. The profound effects of glucocorticoids on bone health are well-known and manifest as increased resorption due to osteoclastogenesis, increased RANK ligand expression, and decreased osteoprotegerin receptor expression.…”
Section: Discussionmentioning
confidence: 99%
“…[ 5 , 9 ] Obese patients had better T-score at FN compared with normal weight individuals, which was consistent with previous findings. [ 13 , 14 ] A third of the study participants with a history of fracture took steroids. The profound effects of glucocorticoids on bone health are well-known and manifest as increased resorption due to osteoclastogenesis, increased RANK ligand expression, and decreased osteoprotegerin receptor expression.…”
Section: Discussionmentioning
confidence: 99%
“…Kt/V yang tinggi biasanya berada pada >1,4. 24,25 Terapi hemodialisis yang lama dan rasio Kt/V yang lebih tinggi dikaitkan dengan terjadinya peningkatan risiko osteoporosis. 24 Semakin lama seseorang melakukan terapi hemodialisis, maka semakin banyak pula mineral larut air seperti urea, kreatinin, fosfat, kalsium dan lainnya yang ikut terbuang.…”
Section: Hasilunclassified