Hemodiafiltration. History, Evolution, Contemporary Standards

Поз, Я. Л.; Строков, А. Г.; Копылова, Ю. В.

doi:10.15825/1995-1191-2014-1-54-64

Cited by 2 publications

(28 citation statements)

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“…This method was proposed by L.V. Genderson et al in 1967 and, owing to the improvements of the filtering membranes and equipment, it has gained a wide application in clinical practice as one of the main RRT methods [ 54 – 56 ].…”

Section: Hemofiltration and Hemodiafiltration In Severe Acute Pancreatitismentioning

confidence: 99%

“…The first experience of applying extracorporeal methods of detoxification in patients with severe pancreatitis (pancreonecrosis) was described in 70–80s of the ХХ century. Those were hemodialysis procedures for acute kidney failure (AKF) [ 55 , 56 ]. Soon, other methods started to be applied.…”

Section: Hemofiltration and Hemodiafiltration In Severe Acute Pancreatitismentioning

confidence: 99%

“…Clearance, or blood purification from the substances with molecular mass up to 20,000 Da, depends on the filtration rate and duration. The feasibility of ultrafiltration rate regulation allows for the water balance control, while an application of replacing electrolyte solutions helps maintain the water-electrolyte balance [ 34 , 54 , 56 ].…”

Section: Hemofiltration and Hemodiafiltration In Severe Acute Pancreatitismentioning

confidence: 99%

“…When blood flow rate increases, blood movement in the hemofilter grows as well but concentration of polarizing substances on the membrane diminishes and the filtration flow increases. Considering the concentration polarization phenomenon, it is recommended to use a relatively high blood flow rate (250–300 ml/min) and maintain the pressure in the hemofilter of about 0.22 bar [ 34 , 54 , 56 , 66 , 67 ].…”

Section: Hemofiltration and Hemodiafiltration In Severe Acute Pancreatitismentioning

confidence: 99%

“…Both low and middle molecular weight toxins are eliminated during HF but low molecular weight toxins are removed worse than during routine hemodialysis. Therefore, HDF method has been proposed in which circulation of dialyzing solution in the hemodialysis filter is added to the above-described procedure providing the diffusion process [ 34 , 51 , 56 , 68 , 72 , 73 ]. Application of the dialyzing solution for CVVH is not required making this method more cost-effective.…”

Section: Hemofiltration and Hemodiafiltration In Severe Acute Pancreatitismentioning

confidence: 99%

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Hemofiltration in Patients with Severe Acute Pancreatitis (Review)

et al. 2020

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Questions regarding the application of extracorporeal detoxification to patients with severe acute pancreatitis have been considered. Hemodialysis, the historically first method of extracorporeal detoxification for such patients, has been also described in the review. Appropriateness of using renal replacement therapy methods and among them continued renal replacement therapy has been shown. Hemofiltration and hemodiafiltration technologies are described in detail including different modes of their application and the possibility of using various types of filters. Available data on hemofiltration for patients with severe acute pancreatitis have been analyzed. Great attention is paid to the unsolved aspects of hemofiltration in severe acute pancreatitis such as determining renal and extrarenal indices; time of starting hemofiltration; selection of volume replacement modes and a buffer system; procedure duration; anticoagulation measures, defining criteria to assess the adequacy of hemofiltration, state severity, and organ dysfunction degree. Further multicenter investigations are necessary to be able to assess the efficacy of the hemofiltration procedures on the basis of the thoroughly worked out and pathogenically grounded protocol using adequate control methods taking into consideration endogenic intoxication phases and intensity of the multiple organ failure syndrome.

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Section: Hemofiltration and Hemodiafiltration In Severe Acute Pancreatitismentioning

confidence: 99%

Section: Hemofiltration and Hemodiafiltration In Severe Acute Pancreatitismentioning

confidence: 99%

Section: Hemofiltration and Hemodiafiltration In Severe Acute Pancreatitismentioning

confidence: 99%

Section: Hemofiltration and Hemodiafiltration In Severe Acute Pancreatitismentioning

confidence: 99%

Section: Hemofiltration and Hemodiafiltration In Severe Acute Pancreatitismentioning

confidence: 99%

See 3 more Smart Citations

Hemofiltration in Patients with Severe Acute Pancreatitis (Review)

et al. 2020

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The effectiveness of on-line hemodiafiltration in patients with chronic kidney disease: risk factors and improving the assessment of fluid excretion values

Zarya¹,

Gurevich²,

Плавинский

2022

Nefrologiâ (St.-Peterbg.)

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Hemodiafiltration on-line (HDF OL) cannot be considered sufficiently studied in terms of its effect on the outcome. THE AIM. To identify the possible relationship of individual anthropometric, laboratory data and parameters of the prescribed treatment regimen with better survival when using the HDF OL. PATIENTS AND METHODS. A retrospective study of the EuCliD database of patients treated with HDF OL in 27 Fresenius Medical Care centers in the Russian Federation during 2014 was conducted. All patients received postdilution HDF OL procedures at least 3 times a week, lasting at least 12 hours a week, with adequacy of Kt/V procedures of at least 1,4. Data from survivors (9616) and deceased (370) patients were compared. The analyzed indicators were: gender, age, treatment experience, body weight, body mass index (BMI), body surface area (BSA), total body water volume (TBW), the volume of distribution (V Urea BCM), presence of diabetes mellitus, coronary heart disease, heart failure, as well as the parameters of the procedure: effective weekly dialysis time, Kt/V, effective in-fusion volume (EIV), effective convection volume (ECV). RESULTS. Risk factors for death in patients with CKD 5D treated with HDF OL include male gender, older age, con-comitant diseases, lower body weight, and BMI, shorter effective weekly dialysis time, lower EIV and ECV values, Kt/V, higher hypercalcemia, hypoalbuminemia, lower hemoglobin levels, higher b2-microglobulin levels, and CRP. Сomparing the normalized BMI, BSA, TBW, V Urea BCM indicators, we identified those that were associated with a high risk of mortality in the population of dialysis patients. CONCLUSION. As a result of this work, two normalized ratios were identified (the median ratio of effective infusion volume to body surface area and the median ratio of effective convection volume to body surface area), which were associated with a high risk of mortality in the population of dialysis patients.

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Hemodiafiltration. History, Evolution, Contemporary Standards

Cited by 2 publications

References 0 publications

Hemofiltration in Patients with Severe Acute Pancreatitis (Review)

Hemofiltration in Patients with Severe Acute Pancreatitis (Review)

The effectiveness of on-line hemodiafiltration in patients with chronic kidney disease: risk factors and improving the assessment of fluid excretion values

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