Hematology of Japanese Quail Treated with Exogenous Stilbestrol Dipropionate and Testosterone Propionate

Abstract

1964. Effect of age, sex and level of fat deposition on major body components in some wood warblers. Auk, 81: 505-513. Sauer, N. G., D. A. Cramer and J. V. Schutze, 1969. The effect of dietary melengestrol acetate (MGA) on body weight gain, percentage carcass fat and fatty acid composition of roaster chickens. Poul- ABSTRACTBlood samples from 90 sexually immature Japanese quail chicks, divided into three groups of 15 males and 15 females per group, were examined to determine the effect of exogenous stilbestrol dipropionate and testosterone propionate. Stilbestrol-treated quail had significantly lower erythrocyte counts, packed cell volume values, hemoglobin concentrations and relative percentage distributions of lymphocytes and showed higher percentages of heterophils and higher total protein content when compared with control birds. Testosterone administration resulted in an elevated erythrocyte count, hematocrit reading and hemoglobin level in the male quail as compared to the control. The mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, total leucocyte count and percentages of basophils and eosinophils were essentially unchanged in either sex by stilbestrol or testosterone therapy.

Cardiovascular and hematological parameters affected by feeding various polychlorinated biphenyls to the single comb white leghorn cockerel

“…This observation is in agreement with other workers (Rehfeld et al 1971, Platonow andFunnell 1971). Several investigators have reported that testosterone increases total erythrocyte concentration in chickens (Domm et al 1943, Domm and Taber 1946, Tanaka and Rosenberg 1955 and in Japanese quail (Nirmalan and Robinson 1972). Also, Fried et at.…”

Hematological changes associated with egg production: estrogen dependence and repeatability

“…However, similar differential effects on estrogendependent reproductive traits have been documented here and in previous studies: tamoxifen treatment causes a robust decrease in egg size (Williams, 2000;Williams, 2001;Wagner and Williams, 2007), whereas exogenous estradiol does not increase egg size (Christians and Williams, 1999;Williams, 1999). Although previous studies have reported that estradiol treatment induces anemia (range -2 to -15%) in domestic fowl (Domm and Taber, 1946;Sturkie and Eiel, 1966), pilgrim geese (Hunsaker, 1968), Japanese quail (Nirmalan and Robinson, 1972;Nirmalan and Robinson, 1973;Garcia et al, 1984), rain quail (Deshmukh and Suryawanshi, 1982) and white-crowned sparrows (Kern et al, 1972), these studies all used non-breeding birds, which would have low baseline levels of endogenous estrogens. To our knowledge, our study is the first to assess effects of physiological levels of estradiol on hematological parameters in laying females specifically within the context of egg production.…”

Migration phenology and winter habitat quality are related to circulating androgen in a long-distance migratory bird

“…Androgens can also interact with other hormones to influence pre‐migratory hyperphagia and fat deposition (Deviche 1995) as well as physiological aspects of condition. Testosterone, for instance, is erythropoietic, stimulating red blood cell synthesis (Domm and Taber 1946, Kern et al 1972, Nirmalan and Robinson 1972). Although some studies have found that haematocrit, the ratio of packed red blood cells to total blood volume, is positively associated with measures of energetic condition (Brown 1996, Potti et al 1999), others have raised concerns about this use of haematocrit, which can be influenced by multiple factors (Fair et al 2007).…”