Hematological values in juvienile periodontitis patients in Ibadan, Nigeria

Dosumu, EB; Asani, MO; Akande, OO; Akingbola, TS

doi:10.4314/ajbr.v5i3.54003

Cited by 1 publication

(4 citation statements)

References 14 publications

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“…Our findings that neither the white blood cells, the neutrophils, nor the lymphocyte values differed between groups corroborate the findings reported for Nigerian adolescents with periodontitis [7] and suggest that the inflammatory load of periodontitis in this young adolescent population is insufficient to influence these counts. The findings of two previous studies conducted among adults suggest lower number of erythrocytes, lower hematocrit values, and lower hemoglobin levels among subjects with periodontitis [3,48], but these findings could not be confirmed in this study of adolescents.…”

Section: Discussionsupporting

confidence: 92%

“…Some of these studies have documented differences in the hematological parameters for subjects with chronic periodontitis compared to healthy subjects, although the findings are not always conclusive [2,5,7,[15][16][17][18]. The variation found in the blood parameters investigated in adult study populations frequently appears to be modest and the values do often not exceed the normal reference values [6].…”

Section: Discussionmentioning

confidence: 89%

“…The results of that study did not indicate the existence of differences between subjects in these disease categories [7], but the question whether young subjects with periodontitis present with hematological values that are different from that of healthy subjects remains unanswered. Thus, it seems natural to acquire more knowledge for young periodontitis cases on standard hematological factors using common laboratory tests.…”

Section: Introductionmentioning

confidence: 94%

“…To the best of our knowledge, only one study has attempted to compare the general hematological values for adolescents according to their periodontal status and the authors only considered subjects with periodontitis, i.e., juvenile periodontitis and chronic periodontitis [7]. The results of that study did not indicate the existence of differences between subjects in these disease categories [7], but the question whether young subjects with periodontitis present with hematological values that are different from that of healthy subjects remains unanswered.…”

Section: Introductionmentioning

confidence: 94%

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Hematological features in adolescents with periodontitis

2011

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The aim of this study was to assess whether adolescent cases of periodontitis present with different hemogram findings than control subjects. This case-control study comprised 87 adolescent cases presenting with clinical attachment loss ≥3 mm in at least two teeth and 73 control subjects. Blood samples were obtained by venipuncture and analyzed in an Abbott Cell-Dyn 3,500 hematology analyzer for values of white blood cells and red blood cells, hemoglobin, mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, red-cell distribution width, platelets, and mean platelet volume. Hematocrit values were obtained using volume fractions read from capillary tubes. The associations between log-transformed hemogram variables with each of the three exposure variables "case status" (yes/no), a "high percent sites with PD ≥4 mm" (yes/no), and a "high percent sites with BOP" (yes/no) were investigated using multivariate linear regression analyses. Periodontitis cases presented with 5% higher values for the mean platelet volume than did controls. Subjects with a high percent sites with probing depth ≥4 mm had eosinophil counts that were on average 27% lower than among subjects with fewer deepened pockets. They also had 7% higher values for the mean platelet volume than did persons with less pocketing. Eosinophil counts and mean platelet volumes may be associated with the parameters of periodontitis in adolescents. While standard hematological testing did not show abnormalities in adolescents with periodontitis compared to healthy controls, eosinophil counts and mean platelet volumes may reflect periodontal inflammation.

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Section: Discussionsupporting

confidence: 92%