Hematological responses to oral administration of iron polymoltose complex in anemic and normal pregnant women: A comparative study

Abstract

Anemia is a common medical disorder affecting a lot of women in pregnancy in the developing countries. Daily oral iron supplementation during pregnancy reduces the prevalence of anemia. In the present study we have compared the hematological responses to oral iron therapy using the formulation of iron poly maltose complex in anemic and normal pregnant women. The haemoglobin (Hb) level and other blood parameters were studied in anemic and non-anemic pregnant women both before and after oral iron therapy. Hemoglobin, iron indicators improved significantly with oral iron therapy and appear to have good compliance and efficacy. This helps us to assess the varied comparative responses in both the categories. The study will be indicative about the rational use of iron in iron deficiency anemia. Key words: Anemia; blood; hemoglobin; deficiency. DOI: 10.3126/jcmsn.v6i3.4067Journal of College of Medical Sciences-Nepal, 2010, Vol. 6, No. 3 pp.1-7

Hematological profile of anemic pregnant women attending antenatal hospital

“…MCH level in their study were 22.56, 23.60 and 24.41 while in the present study it was 21.17, 24.47 and 23.03 respectively. In the present study level of MCHC were 27.42, 27.67 and 28.04 which was comparable with the study of Sunitha et al(2010) 11 .…”

“…The mean of hemoglobin in the anemic population was 10.1 gm/dL, HCT 35%, MCV 87.5fL and RDW-CV 13.5%. In another study by Sunitha et al (2010), RBC level in anemic pregnant women was observed as 3.70, 3.69 and 3.56 in the age group of 15-24, 25-34 and >35 respectively which was similar to the present study where RBC level were 3.52, 3.78 and 3.56 in the age group of <20, 20-25 and >25. In the present study hemoglobin concentration was 8.10, 9.56 and 7.74 in above age group while in the study of Sunitha et al hemoglobin level of pregnant women were 8.27, 8.63 and 9.08 observed in second trimester.…”

Tracking the association of severity of anemia during pregnancy by hematological and relevant biochemical parameters

“…The mean of Hb in the anemic population was 10.1 g/dl, HCT was 35%, MCV was 87.5 fl, and RDW-CV was 13.5%. In another study by Sunitha et al, [20] RBC level in anemic pregnant women was observed as 3.70, 3.69, and 3.56 in the age group of 15-24, 25-34, and >35 years, respectively, while in our study, it was 3.74, 3.76, and 3.44 in the age groups of ≤20, 21-30, .41, while in the present study, it was in the age group ≤20, 21-30 and ≥30 years. In the present study, the level of MCHC was comparable with the study of Sunitha et al [20] …”