Hematological profile of captive bearded capuchin monkeys (Sapajus libidinosus) from Northeastern Brazil

Abstract

Bearded Capuchin or Black-striped Capuchin monkeys (Sapajus lidibinosus) are New World robust capuchin monkeys widely used in medical research. Few data are available concerning hematological reference values for these species, with no studies available from the Northeast region in Brazil. The aim of this study was to determine the hematological reference values for healthy bearded capuchin monkeys and to analyze the influence of sex and age factors. Blood samples were collected from 50 healthy bearded capuchin monkeys housed in captivity. These were analysed for total erythrocyte, hemoglobin, leukocyte and platelet count, packed cell volume (PCV), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH) and mean corpuscular hemoglobin concentration (MCHC). When considering the age factor, significant differences were reported for total erythrocyte count, PCV, hemoglobin, total leucocytes, band neutrophils, eosinophils and lymphocytes (higher in juveniles). Significant sex-associated differences were noted for total erythrocyte count, PCV, hemoglobin (higher in males) and number of lymphocytes (higher in females).We have reported for the first time the hematological profile of bearded capuchin monkeys in captivity in the state of Paraíba, Brazil. These results can contribute for a better understanding of the normal physiology of capuchin monkeys, while demonstrating that factors such as sex and age influence hematological parameters should be taken into consideration in the hematological evaluation of this species. RESUMO: Os macacos-prego (Sapajus lidibinosus) são macacos capuchinhos robustos do Novo Mundo amplamente utilizados na pesquisa médica. Poucos dados estão disponíveis sobre valores de referência hematológicos para essas espécies, e não há estudos na região Nordesteno Brasil. O nosso objetivo foi determinar os valores de referência hematológicos para macacos-prego saudáveis e analisar a influência de fatores como o sexo e a idade. Foram coletadas amostras de sangue de 50 macacos-prego saudáveis alojados em cativeiro. Determinaram-se as contagens de eritrócitos, hemoglobina, leucócitos e plaquetas, hematócrito, volume corpuscular médio (MCV), hemoglobina corpuscular média (MCH) e concentração média de hemoglobina corpuscular (MCHC). Foram encontradas diferenças significativas relacionadas à idade para a contagem total de eritrócitos, hematócrito, hemoglobina, leucócitos totais, neutrófilos em banda, eosinófilos e linfócitos (maior em juvenis). Diferenças significativas associadas ao sexo foram observadas para a contagem total de eritrócitos, hematócrito, hemoglobina (maior nos machos) e número de linfócitos (maior nas fêmeas). Relatamos o primeiro perfil hematológico de macacos-prego alojados em cativeiro no estado da Paraíba, Brasil. Estes resultados contribuem para uma melhor compreensão da normal fisiologia dos macacos-prego e demonstram que fatores como sexo e a idade têm influência e devem ser considerados na sua avaliação hematológica. Palavras-chave: Sapajus libidinosus, hematologia, parâm...

Hematological and biochemical profile of spider monkey (Ateles geoffroyi) in captivity

“…The red blood cells found in this study when comparing them to other non-human primates, indicate a balance of erythropoiesis and destruction of erythrocytes (Ihrig et al, 2001;Yu et al, 2019;Yeo et al, 2019). The hematocrit (HCT) was found to be higher in the monkeys studied, which indicates a state of balance in terms of the water balance regulator mechanism (Armstrong and Johnson, 2018), while the recount of white blood cells (WBC) was found within the normal parameters (García-Feria et al, 2017) and the recount of platelets was similar in comparison to other values in primates (Ferreira et al, 2018). However, the increase of eosinophils found is attributed to helminthic infections in the monkeys studied (Rahimi and Khanaliha, 2018).…”

MICROBIOTA DO TRATO RESPIRATÓRIO INFERIOR DE MACACOS-PREGO (Sapajus spp.) CATIVOS ATRAVÉS DE SEQUENCIAMENTO METAGENÔMICO

“…Todas as amostras resultaram volume suficiente para as análise de microbiota. Os valores hematológicos se mantiveram entre os níveis normais para a espécie (FERREIRA et al, 2018;WIRZ et al, 2008) (Tabela 1).…”

“…submetidos a lavado traqueobrônquico videoassistido para análise metagenômica. Intervalo de referência (FERREIRA et al, 2018;WIRZ et al, 2008*).…”

Haematology, physiological parameters, morphometry and parasitological status of rescued bearded capuchin monkeys (Sapajus libidinosus)

“…Furthermore, laboratory diagnostic tests may help to ensure that the individuals have a good health and welfare level whilst in captivity. 6 Haematological parameters vary with geographical, dietary and environmental factors. 5,6 Hence, it is recommended that data are compared with studies made in the same geographical area when assessing animal health.…”

“…6 Haematological parameters vary with geographical, dietary and environmental factors. 5,6 Hence, it is recommended that data are compared with studies made in the same geographical area when assessing animal health. It is also important to know the age and sex class of the individuals, as certain parameters may be influenced by these factors.…”