Hematological profile of apparently healthy blood donors at a tertiary hospital in Enugu, south east Nigeria: A pilot study

Nubila, Thomas; Ukaejiofo, Ernest O; Nubila, Nkoyo Imelda; Shu, En; Okwuosa, Chukwubuzor N; Okofu, Mary Bassey; Obiora, Benardine C; Shuneba, Irene L

doi:10.4103/2348-0149.135726

Cited by 9 publications

(9 citation statements)

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“…In general, it was observed that in third and fourth time blood donors, the leucocyte count (monocyte and granulocyte) and thrombocyte decreased even though their values were within the normal range, but significantly lower than that of control in this study. The control group values observed is consistent with a recent study in Benin by Nubila et al (2014) and Erhabor et al (2014). Moreover, lymphocyte count was slightly raised.…”

Section: Discussionsupporting

confidence: 92%

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Response of Cellular Elements to Frequent Blood Donations among Male Subjects in Calabar, Nigeria

Okpokam¹,

Okafor²,

Akpotuzor³

et al. 2016

Trends in Medical Research

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Abuse of blood donation is common in Calabar and Nigeria. Research on blood donors has focused on the erythrocyte and iron-related parameters, without considering the other cell lines of the donors. This study examined the effect of frequent blood donations on leucocytes and thrombocytes. One hundred and eighty four subjects aged 18-35 years were used for this study. The subjects were divided into 5 groups thus; 35 (19%) control group, 32 (17.4%) of first time donors, 35 (19%) of second time donors, 41 (22.3%) of third time donors and 41 (22.3%) of fourth time donors. Their full blood counts were evaluated using complete automated cell counter and values obtained were statistically analyzed. Results showed that 63% of the donors were commercial blood donors. Haematocrit (Hct) of first (41.9±0.66%), second (40.1±0.47%), third (39.1±0.54%) and fourth (33.3±0.56%) time male donors decreased progressively as number of times of donation increased, compared with control (43.9±0.55%). Total White Blood Cell (WBC) count significantly (p<0.001) decreased in first, third and fourth time donors, compared with control. Monocytes, granulocytes and platelet counts decreased progressively with repeated blood donations. Lymphocytes increased progressively following repeated blood donations. We therefore, conclude that, serial blood donation decreases Hct, WBC (monocyte and granulocyte) and platelet counts in males and increases lymphocyte count.

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Section: Discussionsupporting

confidence: 92%

“…This finding is Trends Med. Res., 11 (1): 11-19, 2016 consistent with earlier reports by Akpotuzor et al (2008), Okpokam et al (2012), Nubila et al (2014) and Rigas et al (2014). The decrease in PCV found in donors that donated blood 2-4 times could proceed to iron deficiency anaemia.…”

Section: Discussionsupporting

confidence: 80%

Response of Cellular Elements to Frequent Blood Donations among Male Subjects in Calabar, Nigeria

Okpokam¹,

Okafor²,

Akpotuzor³

et al. 2016

Trends in Medical Research

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“…Our data is in agreement with the work of Nubila et al on apparently healthy blood donors. In their study, the average total WBC count among their subjects was significantly higher compared to the control [18]. The reason for increased total WBC count may be due to subclinical bacteremia leading to increased circulating phagocytes.…”

Section: Discussionmentioning

confidence: 75%

Some Hematologic Parameters of Blood Donors at the National Blood Transfusion Service (NBTS), Jos, Nigeria

Lugos¹,

Jb²,

Uy³

et al. 2019

J Blood Disord Transfus

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Introduction: A blood donor is expected to be a healthy individual who donates his or her blood for the medical treatment of patients. World Health Organisation (WHO) recommends that only those with good health status should be accepted as blood donors. Full blood count is a standard haematology test that evaluates a blood sample for a variety of basic parameters and partly applicable in the general screening of health. Normal haemoglobin level is one of the requirements for blood donor suitability. Normal haemoglobin alone does not connote normalcy of other haematologic variables. The full blood count of blood donors may reveal other blood measurements that may contribute to the better assessment of donors and standardisation of blood donor selection. Aim: This research is aimed to evaluate some haematological parameters of assumingly healthy volunteer blood donors at the NBTS (National Blood Transfusion Service), in Jos, Plateau State. Methods: A total of 102 potential healthy blood donors from Jos City and Du Village participated in the study. We obtained 2.5 ml of venous blood aseptically from each donor into an EDTA container and mixed. The full blood counts of the samples were all analysed. The values gotten were subjected to statistical analysis using the SPSS version 23 software. Results: The packed cell volume (PCV), total and differential white blood cell counts and platelet count were significantly different compared to local reference ranges. Further, evaluation of the parameters between genders, locations, age groups and occupations of donors, the platelet, PCV and eosinophil counts differed significantly (p=0.042, 0.00 and 0.029 respectively). The average white blood cells (WBC) count was lower among donors in the rural area (p=0.000). Conclusion: There may be a significant number of apparently healthy blood donors with abnormal haematologic parameters. Full blood count should be included in evaluating blood donors to ensure blood and donor safety.

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“…The literature is very deficient on this subject. Although the studies conducted in different populations, have reported significant differences in different ethnic groups [9].…”

Section: Introductionmentioning

confidence: 99%

Provisional Kuwaiti Children Hematology Reference Range

2016

J Hematol Thromb

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Introduction: Hematology reference ranges (HRR) in the third world countries usually based on results of measurements in advanced countries. Our HRR based on UK HRR since more than 5 decades. However, these parameters are affected by several factors including age, ethnicity, gender and environment. The goal of this study is to establish a provisional HRR for Kuwaiti children (CPK-HRR) and compare it with UK children hematology reference range (CUK-HRR).

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Hematological profile of apparently healthy blood donors at a tertiary hospital in Enugu, south east Nigeria: A pilot study

Cited by 9 publications

References 0 publications

Response of Cellular Elements to Frequent Blood Donations among Male Subjects in Calabar, Nigeria

Response of Cellular Elements to Frequent Blood Donations among Male Subjects in Calabar, Nigeria

Some Hematologic Parameters of Blood Donors at the National Blood Transfusion Service (NBTS), Jos, Nigeria

Provisional Kuwaiti Children Hematology Reference Range

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