Hematological Modulation in Different Phases of Menstrual Cycle

Malipatil, B. S.; Patil, Shilpa

doi:10.7439/ijbr.v4i2.932

Cited by 12 publications

(14 citation statements)

References 21 publications

(21 reference statements)

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“…In vitro studies have suggested that oestrogen enhances granulocyte proliferation. [10] The finding of the present study is in consistent with the finding of Tikare et al, Dixon et al [7,11] Some authors observed that with the increasing aged in women there was a significant fall in total white cells count due to falling of lymphocytes count and marked fall in polymorph counts. No significant aged related variations are seen in men.…”

Section: Discussionsupporting

confidence: 93%

Comparative Study of Total Leucocyte Count and Granulocyte, Agranulocyte Count in Different Age Groups During Menstrual Cycle

Anal¹,

Ningshen²,

Chanu³

2019

jemds

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BACKGROUND Menstrual cycle is the cyclical phenomenon characterized by periodic vaginal bleeding. It influences all the system of the body. Menstruation occurs cyclically at intervals of 21-35 days. Uterine cycle includes menstruation, proliferative and secretory phases. It is due to invisible interplay of different levels of hormones mainly through hypothalamo-pituitary-ovarian-axis. The physiological levels of oestrogen and progesterone influence the leucocyte count. Thus, change in the count might occur when the hormonal balance changes during menstrual cycle and most commonly the organs in the body remain unaffected by this hormonal imbalance. We wanted to study the age-related variations in total leucocyte, granulocyte and agranulocyte count during different phases of menstrual cycle in 1 st professional MBBS students at, Jawaharlal Nehru Institute of Medical sciences (JNIMS), Imphal, Manipur. METHODSIt is a longitudinal study. 50 healthy female medical students in the age group of 18-25 yrs. with regular cycles of 28±2 days duration participated in the study. Students with irregular cycles, gynaecological disorders like endometriosis, fibroid, irregular bleeding, history of prolonged drug intake and history of fever were excluded from the study. Study protocol was explained to the students and informed consent was obtained from each of the students. Institutional ethical committee clearance was obtained. First sample was collected within 48 hours of onset of menstruation, second sample during 8 th -10 th day of menstrual cycle. Third sample was taken during 22 nd -24 th day of menstrual cycle. All the subjects were followed up during a single cycle. Samples were taken in the morning between 9 am-10 am to avoid diurnal variation. Total leucocyte count was determined with Improved Neubauer's chamber using Turk's fluid. Granulocyte-and agranulocyte-count was determined using Leishman's stain under compound microscope. Total leukocyte count and granulocyte and agranulocyte cells were examined during a single cycle. Data collected was statistically analysed. RESULTSThere was increase in total leukocyte count in the 23-25 years age group in different phases of the menstrual cycle as compared to other age groups but was not statistically significant and increased granulocyte count was seen in both the aged groups (17-19), (23-25) years in all phases of menstrual cycle was statistically significant. Agranulocyte count was increased in 23-25 years age group in all phases but was not statistically significant.

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Section: Discussionsupporting

confidence: 93%

Comparative Study of Total Leucocyte Count and Granulocyte, Agranulocyte Count in Different Age Groups During Menstrual Cycle

Anal¹,

Ningshen²,

Chanu³

2019

jemds

View full text Add to dashboard Cite

show abstract

“…years [21]. Studies on hemoglobin, reticulocytes, serum ferritin levels and RDW in women aged 23 to 30 years showed that a single sample was sufficient to report hematological data among women, irrespective of the phase of the menstrual cycle [22].…”

Section: Discussionmentioning

confidence: 99%

The Effect of 6-weeks Military Training on Blood Hematological Parameters in Untrained Recruits in a Military University

Gnanou¹,

Caszo²,

Khalin³

et al. 2014

Med-Science

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“…The increased count may be due to increased 17βestradiol concentration. 19 Decreased in absolute neutrophil count in proliferative phase was not statistically significant. Increased in absolute neutrophil count in secretory phase was statistically significant.…”

Section: Section: Physiologymentioning

confidence: 78%

“…5 The finding of the present study is in consistent with the finding of Tikare et al, Dixon et al 16,6 These results identify significant fluctuation in number and patterns of circulating immune cells in women's immune response. 19 However, the agranulocyte count shows only slight increased during secretory and proliferative phase but was not statistically significant. The increased count may be due to increased 17βestradiol concentration.…”

Section: Section: Physiologymentioning

confidence: 82%

Study of Cyclical Variations of Leukocyte Profile during different Phases of Menstrual Cycle in 1st MBBS Students

Anal¹,

Ningshen²

2019

IJCMR

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Introduction: Menstrual cycle is the periodic shedding of endometrium accompanied by loss of blood during reproductive age.The period extending from the begining of menses to the begining of next one. The regulation of the normal cycle is under the control of neuro hormonal mechanisms with its feedback system present in the hypothalamic-pituitary-ovarian axis. This study was taken up to see the alterations in the immune cells(leukocytes cells) during menstrual cycle in the Medical students of Jawaharlal Institute of Medical sciences.

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Hematological Modulation in Different Phases of Menstrual Cycle

Cited by 12 publications

References 21 publications

Comparative Study of Total Leucocyte Count and Granulocyte, Agranulocyte Count in Different Age Groups During Menstrual Cycle

Comparative Study of Total Leucocyte Count and Granulocyte, Agranulocyte Count in Different Age Groups During Menstrual Cycle

The Effect of 6-weeks Military Training on Blood Hematological Parameters in Untrained Recruits in a Military University

Study of Cyclical Variations of Leukocyte Profile during different Phases of Menstrual Cycle in 1st MBBS Students

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