Hematological Indices of Pregnant Women at the University of Gondar Referral Hospital, Northwest Ethiopia: a Comparative Cross-Sectional Study

Alemu, Aynadis; Abebe, Molla; Terefe, Betelihem; Yesuf, Mohammed; Melku, Mulugeta; Enawgaw, Bamlaku

doi:10.7754/clin.lab.2019.190115

Cited by 11 publications

(10 citation statements)

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“…However, D-dimer was typically elevated during pregnancy, 24 and a comparative cross-sectional study revealed that pregnant women had significantly higher white blood cell count, neutrophil count, and lymphocyte count compared with nonpregnant women. 25 Therefore, pregnancy factors should also be considered when dynamically monitoring changes of laboratory indicators in pregnant women with COVID-19.…”

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confidence: 99%

Laboratory Abnormalities in Pregnant Women with Novel Coronavirus Disease 2019

et al. 2020

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confidence: 99%

Laboratory Abnormalities in Pregnant Women with Novel Coronavirus Disease 2019

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“…In addition, MPV increases during pregancy as a result of hormonal and metabolic changes [24]. Meanwhile, thrombocytopenia is not only a common finding during pregnancy, but also frequent at the onset of AP [25].…”

Section: Discussionmentioning

confidence: 99%

Role of mean platelet volume in hypertriglyceridemia-induced acute pancreatitis during pregnancy

Zeng

Cai

Chen

et al. 2020

BMC Pregnancy Childbirth

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Background Hypertriglyceridemia-induced acute pancreatitis during pregnancy (HTG-APP) is a rare but severe disease with high maternal-fetal mortality risk, which constitutes a systemic inflammatory process accompanied by thrombosis and bleeding disorders. However, the role of mean platelet volume (MPV) in HTG-APP remains unclear. Methods In the retrospective study, we collected 45 patients with HTG-APP as the HTG-APP group and 49 pregnant females with hypertriglyceridemia as the control group. MPV and other relevant variables at onset and remission were collected and compared. Results MPV were significantly higher in the HTG-APP group than in the control group (P < 0.001), and lower in remission than on onset (P = 0.002). According to the severity of acute pancreatitis, all subjects were classified into mild AP (MAP), moderately severe AP (MSAP), and severe AP (SAP) groups. There was a significant difference in MPV on onset among the three groups (P = 0.048), and the SAP patients had the highest levels of MPV. In addition, only in the SAP group, MPV was lower in remission than on onset (P = 0.010). Logistic regression analyses revealed that MPV was significantly associated with SAP (odds ratio = 2.077, 95% confdence interval, 1.038–4.154; P = 0.039). Conclusions These results may indicate an important role of mean platelet volume in evaluating the severity of HTG-APP.

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“…In addition, MPV increases during pregancy as a result of hormonal and metabolic changes [24]. Meanwhile, thrombocytopenia is not only a common nding during pregnancy, but also frequent at the onset of AP [25].…”

Section: Discussionmentioning

confidence: 99%

“…Since the main purpose of this study was to distinguish SAP in the early stage of the disease, MSAP and MAP were merged with the Non SAP group, while AP with SAP was considered the SAP group. We de ned gestational age as the rst (before 12 weeks), second (13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27) weeks), and third trimesters (28 weeks until delivery).…”

Section: Patient Enrollmentmentioning

confidence: 99%

Role of mean platelet volume in hypertriglyceridemia-induced acute pancreatitis during pregnancy

Zeng

Cai

Chen

et al. 2020

Preprint

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Background: Hypertriglyceridemia-induced acute pancreatitis during pregnancy (HTG-APP) is a rare but severe disease with high maternal-fetal mortality risk, which constitutes a systemic inflammatory process accompanied by thrombosis and bleeding disorders. However, the role of mean platelet volume (MPV) in HTG-APP remains unclear.Methods: In the retrospective study, we collected 45 patients with HTG-APP as the HTG-APP group and 49 pregnant females with hypertriglyceridemia as the control group. MPV and other relevant variables at onset and remission were collected and compared. Results: MPV were significantly higher in the HTG-APP group than in the control group (P < 0.001), and lower in remission than on onset (P = 0.002). According to the severity of acute pancreatitis, all subjects were classified into mild AP (MAP), moderately severe AP (MSAP), and severe AP (SAP) groups. There was a significant difference in MPV on onset among the three groups (P = 0.048), and the SAP patients had the highest levels of MPV. In addition, only in the SAP group, MPV was lower in remission than on onset (P = 0.010). Logistic regression analyses revealed that MPV was significantly associated with SAP (odds ratio = 2.077, 95% confdence interval, 1.038-4.154; P = 0.039). Conclusions: These results may indicate an important role of mean platelet volume in evaluating the severity of HTG-APP.

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Hematological Indices of Pregnant Women at the University of Gondar Referral Hospital, Northwest Ethiopia: a Comparative Cross-Sectional Study

Cited by 11 publications

References 0 publications

Laboratory Abnormalities in Pregnant Women with Novel Coronavirus Disease 2019

Laboratory Abnormalities in Pregnant Women with Novel Coronavirus Disease 2019

Role of mean platelet volume in hypertriglyceridemia-induced acute pancreatitis during pregnancy

Role of mean platelet volume in hypertriglyceridemia-induced acute pancreatitis during pregnancy

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