Hematological and CD4+ T- cell count reference interval for pregnant women attending antenatal care at Hawassa University Comprehensive Specialized Hospital, Hawassa Southern Ethiopia

Gebere, Yidnekachew Fiseha; Bimerew, Lealem Gedefaw; Adissu, Wondimagegn; Fenta, Demissie Assegu

doi:10.1371/journal.pone.0249185

Cited by 7 publications

(2 citation statements)

References 28 publications

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“…33,34 Wright's stained blood films were inspected under a microscope to determine the red cell morphology. [35][36][37] The typical methods for collecting stool samples were used to acquire about 2 grams of a sample for parasite analysis. Intestinal parasites were evaluated using a direct wet mount after samples were fixed with 10% formalin.…”

Section: Sample Collection Processing and Analysismentioning

confidence: 99%

Untitled

2024

HTIJ

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Background: As anemia is a prevalent condition in geriatrics and old age and its frequency proportionately increases with age, leading to severe consequences; any magnitude of it is now recognized as a risk factor for any adverse outcomes: decreased quality-of-life, hospitalization, morbidity, and mortality. Despite its clinical importance, the problem is not widely recognized. Therefore, regular surveillance could provide evidence-based local data required for interventions. This study is aimed to assess the prevalence and associated factors of anemia among elderly patients in eastern Ethiopia.Methods: From June 20 to July 30, 2022, a cross-sectional study centered in an institution was carried out, enrolling 381 elderly patients. Direct interviewing and review of medical records were used to gather socio-demographic and clinical data. Each participant provided a venous blood sample to determine total blood cell count and blood peripheral film examination; to identify hemoparasites and the morphological type of anemia. Using SPSS version 25, descriptive statistical analysis and bivariate and multivariate logistic regressions were used, and statistical significance was set at p<0.05.Result: Anemia was seen in 40.4% of participants, mild, moderate, and severe anemia accounts for 71.1%, 23.1%, and 5.8%, respectively. Normocytic normochromic anemia was seen in 55.13% of cases, and microcytic hypochromic in 37.18%. The anemia was substantially correlated with being male [AOR=0.352 95% CI: 0.174, 0.708], having a lower socioeconomic status [AOR=0.041 95% CI: 0.011, 0.156], and eating meat less than once per week [AOR=0.301 95% CI: 0.114, 0.793]. Conclusion and recommendation:The prevalence of anemia among elderly patients in this area was found to be a severe public health problem. Mild anemia was the predominant type. Identified risk factors should be considered to prevent and control anemia, and screening for anemia among the elderly should be a part of their routine management.

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Section: Sample Collection Processing and Analysismentioning

confidence: 99%

Untitled

2024

HTIJ

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“…Pregnancy is a state characterized by profound physiological, hematological, and immunological changes. [ 1 ] Thrombocytopenia (TCP) is the second most common hematological change in pregnant women and a notable source of maternal and neonatal morbidity and mortality. [ 2 , 3 ] The global prevalence of TCP among pregnant women is 8.4% and around one-tenth of pregnant women are suffered worldwide.…”

Section: Introductionmentioning

confidence: 99%

Thrombocytopenia and associated factors among pregnant women attending antenatal care at Hiwot Fana Comprehensive Specialized Hospital, Eastern Ethiopia: A cross-sectional study

Arkew,

Asmerom,

Sileshi

et al. 2024

Medicine

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Thrombocytopenia (TCP) is the second most common hematological change during pregnancy and is considered as a major source of maternal and neonatal morbidity and mortality. Despite its effects to morbidity and mortality, it is frequently ignored or disregarded, particularly in resource-limited nations. Thus, the purpose of this study was to determine the prevalence of thrombocytopenia and associated factors among pregnant women attending antenatal care at Hiwot Fana Comprehensive Specialized University Hospital, Eastern Ethiopia from June 20 to August 30, 2022. A hospital-based cross-sectional study was conducted among 199 pregnant women selected through a systematic sampling technique. Ethical approval was obtained from the Ethics Review Committee of Haramaya University. Data related to sociodemographic and reproductive variables were collected using structured questionnaires. Four milliliters of venous blood were collected from each study participant and a complete blood cell count was determined using UniCel DxH 800 hematology analyzer. Logistic regression analysis was done to assess the association between TCP and independent variables and P < .05 was considered statistically significant. In this study, the prevalence of TCP was 14.1% (95% CI: 9.6–19.7). Of them, 10 (35.7%), 12 (42.9%), and 4 (21.4%) had mild, moderate, and severe TCP, respectively. Having more than 3 children (adjusted odds ratio, AOR = 7.90, 95% CI: 2.60, 24.3), no antenatal care follow-up (AOR = 7.90, 95% CI: 2.40–26.2), being in the second and third trimester (AOR = 6.90, 95% CI: 1.70, 28.9 and AOR = 5.04, 95% CI: 1.12, 22.7, respectively), and history of heavy menstrual bleeding (AOR = 4.03, 95% CI: 1.25, 13.1) were significantly associated with TCP. TCP is a public health problem among pregnant women in the study area. Having more than 3 children, lack of antenatal care follow-up, being in the second and third trimesters, and having history of heavy menstrual bleeding was significantly associated with TCP. As a result, regular platelet count monitoring and appropriate intervention approaches based on identified predictors should be explored to mitigate adverse outcomes in pregnant women.

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Micro and small scale enterprises growth and ownership structure in Hawassa city, Sidama region, Ethiopia

Shitaye

2022

Cogent Economics & Finance

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Hematological and CD4+ T- cell count reference interval for pregnant women attending antenatal care at Hawassa University Comprehensive Specialized Hospital, Hawassa Southern Ethiopia

Cited by 7 publications

References 28 publications

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Thrombocytopenia and associated factors among pregnant women attending antenatal care at Hiwot Fana Comprehensive Specialized Hospital, Eastern Ethiopia: A cross-sectional study

Micro and small scale enterprises growth and ownership structure in Hawassa city, Sidama region, Ethiopia

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