Hemangiopericytoma in the Trigone of the Lateral Ventricle-Case Report-

Abstract

A 40-year-old male presented with hemangiopericytoma in the lateral ventricle manifesting as headaches persisting for 6 months associated with vomiting and visual obscurations for one month. Computed tomography and magnetic resonance imaging of the brain showed a large tumor in the trigone of the right lateral ventricle. The highly vascular tumor was completely excised. The histological diagnosis was hemangiopericytoma. Hemangiopericytoma is rarely located in the lateral ventricle and is difficult to differentiate from meningioma by neuroimaging methods.

Hemangiopericytoma in the Lateral Ventricle -Case Report-

“…1,2,5,6,9,18,19) The features of these and the present case are summarized in Table 1. Intraventricular HPCs occur in males more frequently, with mean age of 39 years, which is consistent with the age and sex distribution of HPCs in other locations.…”

“…An intraventricular SFT in the third ventricle could be differentiated from HPC based on the absence of local recurrence after 3.5 years, and strong positive staining for CD34 and bcl-2. 13) In the present case, the specimen was scarcely positive for CD34, but with 19) 41/M lt lateral ventricle subtotal removal/ total removal yes not described Abrahams et al (1999) 1) 40/M third ventricle total removal not described not described Hattingen et al (2003) 9) 43/F lt lateral ventricle total removal not described not described Desai et al (2004) 6) 40/M rt lateral ventricle total removal yes no (1 yr follow up) Al-Brahim et al (2004) 2) 53/F rt lateral ventricle total removal not described not described Bunai et al (2008) abundant reticulin fibers. These histological and immunohistochemical findings were consistent with HPC, and so the final diagnosis was HPC.…”

“…18) Intracranial HPCs are especially uncommon, consisting of approximately 2% of meningeal tumors, 8,11) and less than 1% (0.2% in Japan) of all intracranial tumors. Intracranial HPCs bear many similarities to meningiomas, such as growth with attachment to the dura mater, commonly in the supratentorial component, adhering to the falx, sagittal sinus, 6,8,10) and macroscopically distinct appearance from the adjacent brain tissue. Intracranial HPCs were defined as histologically and immunohistochemically distinct from meningiomas after the first case of HPC arising from the dura mater was reported.…”

“…16) However, HPCs are more aggressive tumors because of the tendency to recur and metastasize even after gross total removal (WHO grade II or III). 6) Few intracranial HPCs occur in the sella, pineal regions, or in the intraventricular regions. 6) Only 7 cases of intraventricular HPC have been reported.…”

“…6) Only 7 cases of intraventricular HPC have been reported. 1,2,5,6,9,18,19) We report a case of intraventricular HPC located in the trigone of the right lateral ventricle, and discuss the histological differential diagnosis, especially for meningiomas and solitary fibrous tumors (SFTs).…”