Helicobacter pylori Infection in Recurrent Abdominal Pain

Frank, Friederike; Stricker, Tamar; Stallmach, Thomas; Braegger, Christian

doi:10.1097/00005176-200010000-00017

Cited by 55 publications

(34 citation statements)

References 18 publications

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“…Many investigators from different parts of the world have observed an association between H. pylori and recurrent abdominal pain,[79–81] whereas many others have failed to find an association between the same. [82–87] Finally, a meta-analysis of 45 studies in children with H. pylori and outcome found a weak and inconsistent evidence of an association between H. pylori infection and classic recurrent abdominal pain.…”

Section: H Pylori–related Pathological Conditionsmentioning

confidence: 99%

Helicobacter pylori infection in children

Rajindrajith

Devanarayana

Silva

2009

Saudi J Gastroenterol

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Helicobacter pylori infection is a common problem in pediatric practice, and its acquisition is related with poor socioeconomic conditions. Although the organism is thought to be responsible for many diseases, only a handful of them have a direct causal relationship. At present, only a small number of children with well-defined clinical syndromes are benefited from testing and treatment. The treatment should include at least two antibiotics with a proton pump inhibitor.

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Section: H Pylori–related Pathological Conditionsmentioning

confidence: 99%

Helicobacter pylori infection in children

Rajindrajith

Devanarayana

Silva

2009

Saudi J Gastroenterol

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“…[3][4][5][6][7][8] To avoid, induction of secondary resistance in the infecting H. pylori strains, as well as further expensive and risky investigations, eradication treatment should reach at least 90% in per-protocol analysis. However, most parents (and children when old enough to understand) are willing to have a treatment, although there is no conclusive evidence, that eradication of the infection will improve their symptoms of dyspepsia.…”

Section: Introductionmentioning

confidence: 99%

Eradication rate of Helicobacter Pylori infection is directly influenced by adherence to therapy in children

et al. 2017

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Adherence to therapy is a very important factor for the outcome and has to be assessed when evaluating the outcome of an H. pylori eradication regimen in order to understand the reasons of treatment failure. As we treated only after evaluation of the resistance of the H. Pylori strains, we were expecting to reach the given objective of 90% successful treatment. Children with adherence to treatment above 90% had a successful outcome of 89,9%, whereas nonadherent had a successful outcome of 36,8%. This is the first time that adherence has been assessed accurately.

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“…Birçok çalışmada H. pylori ile TKA arasında ilişki bulunmamış ve TKA olan ço-cuklarda H. pylori taramasının gerekli olmadığı belirtilmiştir. [15][16][17][18][19][20] Kronik gastrik inflamasyonun sitokin salınımı aracılığı ile viseral hiperaljeziye yol açtığı ve H. pylori'nin rektoviseral gastrokolonik refleksin tetiklenmesinde rol alabileceği düşünül-mektedir. 8 Ülkemizde sağlıklı çocuklarda H. pylori sıklığı 13 C-üre nefes testi ile %50-56 olarak bulunmuştur, TKA'sı olan çocukların %36-49'unda ise H. pylori organik neden olarak bildirilmiştir.…”

Section: Bulgularunclassified

Recurrent Abdominal Pain in Children: Is it Organic or Functional?

Kırşaçlıoğlu¹,

Kuloğlu²,

Üstündağ³

et al. 2016

Turkiye Klinikleri J Pediatr

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74Çocuklarda Tekrarlayan Karın Ağrısı:Organik mi, Fonksiyonel mi?Ö ÖZ ZE ET T A Am ma aç ç: : Çocuklarda sık görülen bir durum olan tekrarlayan karın ağrısı organik ya da fonksiyonel olabilmektedir. Bu çalışmada, tekrarlayan karın ağrısına yol açan parazitozlar, çöl-yak hastalığı, idrar yolu enfeksiyonu, Helicobacter pylori enfeksiyonu gibi organik nedenlerin değerlendirilmesi ve fonksiyonel gastrointestinal bozuklukların belirlenmesi amaçlanmıştır. G Ge er re eç ç v ve e Y Yö ön nt te em ml le er r: : Çalışmaya başka bilinen bir hastalığı olmayan ve ilaç kullanmayan, en az üç ay süreyle en az üç kez tekrarlayan karın ağrısı olan çocuklar dâhil edildi. Ağrı karakteri, laboratuvar bulguları, radyolojik incelemeler, histopatolojik bulgular geriye dönük olarak değer-lendirildi. B Bu ul lg gu ul la ar r: : Çalışmaya ortalama yaşı 10,7±3,4 (4-17) yıl olan, ortanca 12 (3-20) aydır tekrarlayan karın ağrısı olan 151 (%57,6'sı kız) hasta alındı. Roma III kriterlerine göre; 81 (%53,6) hastada fonksiyonel gastrointestinal bozukluk, 70 (%46,4) hastada karın ağrısına yol açabilecek organik bir neden saptandı. Fonksiyonel ve organik nedenler arasında yaş, cinsiyet, ağrı süresi ve ağrı özellikleri açısından fark bulunmadı. Fonksiyonel gastrointestinal bozukluklar arasında en sık (%62,9) fonksiyonel karın ağrısı saptandı. Organik nedenli tekrarlayan karın ağrısı olan hastaların %46'sında Helicobacter pylori enfeksiyonu, %10,5'inde dışkıda parazit yumurtası, %3,9'unda biyopsi destekli çölyak hastalığı saptandı. S So on nu uç ç: : Fonksiyonel ve organik karın ağrısının ayırt edilmesinde yaş, cinsiyet, ağrı özellikleri, eşlik eden başka yakınmalar, fizik inceleme bulguları açısından bir fark saptanmamıştır. Çölyak hastalığı, tekrarlayan karın ağrısı olan bütün çocuklarda taranmalıdır.A An na ah h t ta ar r K Ke e l li i m me e l le er r: : Çocuk; çölyak hastalığı; karın ağrısı; Helicobacter pylori A AB BS S T TR RA AC CT T O Ob bj je ec ct ti iv ve e: : Recurrent abdominal pain is common in childhood, it may be functional or associated with organic disease. Evaluation of organic causes of recurrent abdominal pain such as parasitic enfestations, celiac disease, uriner tract infection, Helicobacter pylori infection and determine functional gastrointestinal disorders in children were aimed in the study. M Ma at te er ri ia al l a an nd d M Me et th ho od ds s: : Children with recurrent abdominal pain more than three times in frequency, for at least three months duration, without a known medical history and drug usage were recruited to study. Medical records were evaluated for pain characteristics, laboratory, radiological and histopathological findings, retrospectively. R Re es su ul lt ts s: : A hundred and fifty-one children [(57.6% female, mean age 10.7±3.4 (4-17) years] with recurrent abdominal pain for median 12 (3-20) months, were recruited to study. According to Rome III criteria; 81 (53.6%) patients had functional gastrointestinal disorders, 70 (46.4%) patients had an organic etiology. There was no difference between function...

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Helicobacter pylori Infection in Recurrent Abdominal Pain

Cited by 55 publications

References 18 publications

Helicobacter pylori infection in children

Helicobacter pylori infection in children

Eradication rate of Helicobacter Pylori infection is directly influenced by adherence to therapy in children

Recurrent Abdominal Pain in Children: Is it Organic or Functional?

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