Hefen der Gattung Trichosporon Identifizierung, Epidemiologie und Bedeutung der dermatologischen Krankheitsbilder

Abstract

Based on molecular data, the genus Trichosporon was recently reclassified. Six human pathogenic species, which are closely related to specific types of infections can be differentiated. By means of commercial test systems and simple key criteria according to Gueho et al. [15], 44 isolates that had been identified as Tr. cutaneum between 7/92 and 1/96, were reclassified. The evaluation of clinical data also included 66 isolates that had not been preserved, and 27 strains of Tr. inkin. Trichosporon species were found in 4.8% of all yeast isolates (3.8% Tr. cutaneum, 1% Tr. inkin). Nearly every other isolate of Tr. cutaneum was cultivated from nail material, while Tr. inkin was mainly isolated from skin in the anogenital region. In 38 cases, reclassification revealed Tr. mucoides; Tr. ovoides and Tr. asteroides were identified in 3 cases each, while Tr. asahii, an especially remarkable pathogen in systemic mycoses, was not found. Clinically, isolates of Tr. mucoides were predominant in toenail mycoses which might be considered in the therapy of onychomycosis. Furthermore, isolates from the skin should be evaluated with respect to the increasing incidence of systemic Trichopsoron mycoses.

Mycotic infections of the penis

“…Yeasts of the genus Tichosporon are occasionally demonstrated as components of the normal human flora, especially of the anogenital region (Mayser et al, 1996). Yeasts of the genus Tichosporon are occasionally demonstrated as components of the normal human flora, especially of the anogenital region (Mayser et al, 1996).…”

Mycological examinations on the fungal flora of the chicken comb

“…Its taxonomic position seems to be not yet final. Recent reclassification pointed out that this species is rather heterogenic 24,25 . As a recently defined species Trichosporon mucoides is established.…”

“…cutaneum / Tr. mucoides is important as a cause of athlet's foot 26 and as a participating agent in onychomycosis, 25 also as a trigger of systemic endomycoses especially in immunosuppressed hosts 27,28 . In the veterinary–avian field, however, it has been detected only sporadically 19 .…”

“…Within the 149 yeast isolates, Trichosporon inkin ( Sarcinosporon inkin ) was seen eight times – also without any relations to clinical changes. In human dermatology this fungus is thought to have an affinity to the anogenital skin, but without notable clinical symptoms 24,25 . Because of the sarcina‐like endospores in some hyphal endings of its true mycelium this fungus is no longer a member of the genus Trichosporon , but so far it is the sole member in its own genus ‘ Sarcinosporon ’, namely S. inkin 29…”

Characterization of the medically important yeast Trichosporon mucoides and its close sister Trichosporon dermatis by traditional and advanced technologies

“…Since Guého et al (1992) described the species to accommodate an atypical group of yeasts in Trichosporon beigelii, several studies have reported T. mucoides as a causative agent of white piedra and onychomycosis, as well as fungal septicaemia in humans (e.g. Capoor et al, 2013; Guého et al, 1994; de Hoog & Guého, 2005;Lacasse & Cleveland, 2009;Mayser et al, 1996). Trichosporon dermatis, a sibling species of T. mucoides, was recognized by Sugita et al (2001a) from a yeast strain that was originally identified as Cryptococcus humicola but was later distinguished from the species sequence comparison of the D1/D2 region of the large subunit of the 28S rRNA gene.…”