Heavy Metal–Induced Gene Expression in Plants

Memon, Abdul Razaque; Meraklı, Nuriye; Kusur, Fatma; Demircan, Orcan; Ayaz, Emine; Memon, Muhammet

doi:10.1007/978-3-030-41552-5_7

Cited by 9 publications

(4 citation statements)

References 155 publications

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“…They are suggested to do the same function as their counterpart in Arabidopsis thaliana. Interactome analysis showed that all four HMAs interact with different metal transporters and metal chaperons (Memon 2020). The primary approach to generating interactome protein analysis is to check for the specificity in structure and function between plant species in Brassicaceae and compare this data to that of A. thaliana.…”

Section: Discussionmentioning

confidence: 99%

Comparative Structural Analysis of Heavy Metal ATPases in Arabidopsis thaliana, Arabidopsis halleri, Brassica rapa, and Brassica juncea

Memon

Meraklı

2022

Turkish JAF Sci.Tech.

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Arabidopsis thaliana has eight genes encoding members of the type P1B heavy metal–transporting ATPase, subfamily of the P-type ATPases. We focused our study on four ATPases, mainly HMA1, HMA2, HMA3, and HMA4, which are closely related and most similar in their sequences. We carried out the bioinformatics analysis of these metal ATPases and obtained their structure in A. thaliana, A. halleri, and the other heavy metal accumulators in Brassica spp. A. thaliana is a model plant for research because of the duplications and other evolutionary events. These evolutionary events provided a chance to elucidate their regulation and function in the cell. All previous bioinformatics analyses have given some information about their structure, but not much work has been done on their structural components and interactome analysis. Experimental determination of 3D structures is essential to understand better these proteins’ function, which is crucial for the proper functioning of all plant cellular processes. Especially, docking sites and domains need to be worked out to understand the role of these transporter proteins and their interaction in plant cells. These bioinformatic analyses will help the researcher understand these ATPases’ role in detoxifying the toxic metals from the cells of accumulator plants. Further research on gene cloning, gene expression, and generating new accumulator plants for phytoremediation is needed to reclamation polluted soils from toxic heavy metals.

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Section: Discussionmentioning

confidence: 99%

Comparative Structural Analysis of Heavy Metal ATPases in Arabidopsis thaliana, Arabidopsis halleri, Brassica rapa, and Brassica juncea

Memon

Meraklı

2022

Turkish JAF Sci.Tech.

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“…Tobacco (Nicotiana tabacum) plants accumulated relatively high concentrations of HMs in the leaves [70]. Among many vegetable species tested, specific species in the Brassicaceae family accumulated the highest amounts of Cr, although Cr translocation from root to shoot was extremely limited in almost all species tested [71,72]. An investigation of several African vegetable species showed that matembele (Ipomoea batatas) plants had the highest HM content, followed by mchicha (Amaranthus hybridus), eggplant (Solanum melongena), and bamia (Abelmoschus esculentus) [65].…”

Section: Plant Type Growth Stage and Growth Conditionsmentioning

confidence: 99%

Heavy Metal Contamination in Agricultural Soil: Environmental Pollutants Affecting Crop Health

et al. 2023

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Heavy metals and metalloids (HMs) are environmental pollutants, most notably cadmium, lead, arsenic, mercury, and chromium. When HMs accumulate to toxic levels in agricultural soils, these non-biodegradable elements adversely affect crop health and productivity. The toxicity of HMs on crops depends upon factors including crop type, growth condition, and developmental stage; nature of toxicity of the specific elements involved; soil physical and chemical properties; occurrence and bioavailability of HM ions in the soil solution; and soil rhizosphere chemistry. HMs can disrupt the normal structure and function of cellular components and impede various metabolic and developmental processes. This review evaluates: (1) HM contamination in arable lands through agricultural practices, particularly due to chemical fertilizers, pesticides, livestock manures and compost, sewage-sludge-based biosolids, and irrigation; (2) factors affecting the bioavailability of HM elements in the soil solution, and their absorption, translocation, and bioaccumulation in crop plants; (3) mechanisms by which HM elements directly interfere with the physiological, biochemical, and molecular processes in plants, with particular emphasis on the generation of oxidative stress, the inhibition of photosynthetic phosphorylation, enzyme/protein inactivation, genetic modifications, and hormonal deregulation, and indirectly through the inhibition of soil microbial growth, proliferation, and diversity; and (4) visual symptoms of highly toxic non-essential HM elements in plants, with an emphasis on crop plants. Finally, suggestions and recommendations are made to minimize crop losses from suspected HM contamination in agricultural soils.

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“…In contrast, upon comparison of the genetic backgrounds, it can be observed that hyperaccumulator plants possess genes responsible for heavy metal accumulation that are also present in non-hyperaccumulator plants. Nevertheless, the expression and regulation of these genes differ [44][45][46]. These genes are involved in the accumulation, transfer and overall plant detoxification [47].…”

Section: Hyperaccumulators and Non-hyperaccumulatorsmentioning

confidence: 99%

The Effect of Cadmium on Plants in Terms of the Response of Gene Expression Level and Activity

Moravčíková

Žiarovská

2023

Plants

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Cadmium (Cd) is a heavy metal that can cause damage to living organisms at different levels. Even at low concentrations, Cd can be toxic to plants, causing harm at multiple levels. As they are unable to move away from areas contaminated by Cd, plants have developed various defence mechanisms to protect themselves. Hyperaccumulators, which can accumulate and detoxify heavy metals more efficiently, are highly valued by scientists studying plant accumulation and detoxification mechanisms, as they provide a promising source of genes for developing plants suitable for phytoremediation techniques. So far, several genes have been identified as being upregulated when plants are exposed to Cd. These genes include genes encoding transcription factors such as iron-regulated transporter-like protein (ZIP), natural resistance associated macrophage protein (NRAMP) gene family, genes encoding phytochelatin synthases (PCs), superoxide dismutase (SOD) genes, heavy metal ATPase (HMA), cation diffusion facilitator gene family (CDF), Cd resistance gene family (PCR), ATP-binding cassette transporter gene family (ABC), the precursor 1-aminocyclopropane-1-carboxylic acid synthase (ACS) and precursor 1-aminocyclopropane-1-carboxylic acid oxidase (ACO) multigene family are also influenced. Thanks to advances in omics sciences and transcriptome analysis, we are gaining more insights into the genes involved in Cd stress response. Recent studies have also shown that Cd can affect the expression of genes related to antioxidant enzymes, hormonal pathways, and energy metabolism.

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Heavy Metal–Induced Gene Expression in Plants

Cited by 9 publications

References 155 publications

Comparative Structural Analysis of Heavy Metal ATPases in Arabidopsis thaliana, Arabidopsis halleri, Brassica rapa, and Brassica juncea

Comparative Structural Analysis of Heavy Metal ATPases in Arabidopsis thaliana, Arabidopsis halleri, Brassica rapa, and Brassica juncea

Heavy Metal Contamination in Agricultural Soil: Environmental Pollutants Affecting Crop Health

The Effect of Cadmium on Plants in Terms of the Response of Gene Expression Level and Activity

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