Heating and structural alterations in cartilage under laser radiation

Sobol, Emil N.; Китай, М. С.; Jones, Nicholas; Sviridov, Аlexander P.; Milner, Thomas E.; Wong, Brian J. F.

doi:10.1109/3.753657

Cited by 41 publications

(31 citation statements)

References 16 publications

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“…Laser reshaping of cartilage has been well documented in both experimental studies [10,14,17,18] and controlled clinical trials [19]. While photography and time-dependent measurements of stress relaxation have illustrated the shape changes in tissue which accompany rapid laser heating, studies to date have neither examined the degree of specimen curvature nor quantitatively investigated memory effects.…”

Section: Discussionmentioning

confidence: 99%

Shape retention in porcine‐septal cartilage following Nd:YAG (λ = 1.32 μm) laser‐mediated reshaping

2001

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Section: Discussionmentioning

confidence: 99%

Shape retention in porcine‐septal cartilage following Nd:YAG (λ = 1.32 μm) laser‐mediated reshaping

2001

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“…A theoretical model was developed that considers stress relaxation and structural alterations as one process in which the kinetics is governed (limited) by mass transfer processes [18]. In this model, a threshold temperature exists at which portions of the cartilage matrix may move relative to neighboring regions [3,18].…”

Section: Dynamics Of Ir Light Transmission In Cartilage In Relation Tmentioning

confidence: 99%

Laser reshaping and regeneration of cartilage

et al. 2007

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Demonstration of laser-induced stress relaxation in cartilage in 1992 led to the development of a novel laser surgical procedure in otolaryngology for the non-ablative reshaping of cartilage. Follow-up studies found that non-destructive laser irradiation may activate regeneration processes in cartilaginous tissue. Ongoing studies seek to characterize the physical, chemical and biological processes and mechanisms involved in the reshaping and regeneration of deformed and diseased cartilage under moderate laser heating. A theoretical model is developed considering laser-induced stress relaxation in cartilage as a process of micropore formation. Results obtained provide scientific and engineering data for development of novel laser surgical procedures for correction of the nasal septum and treatment of spine disc cartilage diseases. This review is aimed to present state of art and recent results in laser -induced reshaping and regeneration of cartilage.Histological cross-section of porcine nasal septal cartilage after laser reshaping using 1.56 µm laser radiation with power of 1.5 W, spot diameter 2 mm, exposure time of 5 s. Stained with Hematoxylin and Eosin, ×400

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“…During laser irradiation, mechanically deformed cartilage undergoes a subtle change in material properties that permits tissue to be reshaped into new stable configurations [5,6,11,12,[14][15][16][17][18][19][20][21][22]. Although the mechanism responsible for shape change has not been conclusively established, the process is thought to involve a combination of collagen denaturation, alteration of weak van der Waals bonds between proteoglycan molecules, and/or water flux [9,18].…”

Section: Introductionmentioning

confidence: 99%

Characterization of temperature dependent mechanical behavior of cartilage

et al. 2003

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The anisotropic mechanical behavior of cartilage was quantitatively analyzed in the transversely and longitudinally oriented specimens. Viscoelastic behavior appeared to be strongly dependent on the water content. Using empirically determined estimates of the transition zone temperature range accompanying stress relaxation, the activation energy for stress relaxation was calculated using time and temperature superposition theory and WLF equation. Further investigation of the molecular changes, which occur during laser irradiation, may assist in understanding the thermal and mechanical behavior of cartilage and how the reshaping process might to be optimized.

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Heating and structural alterations in cartilage under laser radiation

Cited by 41 publications

References 16 publications

Shape retention in porcine‐septal cartilage following Nd:YAG (λ = 1.32 μm) laser‐mediated reshaping

Shape retention in porcine‐septal cartilage following Nd:YAG (λ = 1.32 μm) laser‐mediated reshaping

Laser reshaping and regeneration of cartilage

Characterization of temperature dependent mechanical behavior of cartilage

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