“…6 HSPs are believed to have a number of cell protective functions such as assembly/disassembly of proteins, interaction with surface receptors and antigen presentation. 2,7 Overexpression of HSPs has been observed in certain cancers (breast, uterine cervix, lung, pancreas, ovary, liver, leukaemia and oral cavity). 1±4,6,8 The physiopathological activity of HSPs in tumour processes is not yet known, but it is related to cell growth and differentiation, and/or may interact with oncogenic products such as p53.…”