Heat capacity of solid-state biopolymers by thermal analysis

Calculation of the standard molal thermodynamic properties of crystalline peptides

“…Here, values of C o P for polytryptophan from two different studies are plotted as a function of temperature. The value of C o P from Di Lorenzo et al (1999) at 25°C, 207 J K À1 mol À1 , is 7.4% larger than the one reported in , 191.7 J K À1 mol À1 . By comparison, the estimated C o P for polytryptophan generated in this study is between these two values, 202.0 J K À1 mol À1 .…”

“…In order to extend the relatively sparse thermodynamic data set available in the literature for crystalline peptides (Hutchens et al, 1969a,b;Domalski, 1972;Finegold and Kumar, 1981;Roles and Wunderlich, 1991;Diaz et al, 1992;Zhang et al, 1996;Di Lorenzo et al, 1999;Drebushchak et al, 2008), the group additivity method for estimating thermodynamic properties of organic compounds (e.g., Benson and Buss, 1958;Benson, 1968;Hearing, 1988, 1993;Amend and Helgeson, 1997b;Richard and Helgeson, 1998) has been adopted. In this approach, the contribution of a group of atoms in a molecule to the thermodynamic properties of the entire compound is determined.…”

“…(5) to the data. The circular and square symbols in (f) refer to data from Di Lorenzo et al (1999) and , respectively. The solid circles in (b) are values of C o p not included in the regression.…”

“…d Zhang et al (1996). e Di Lorenzo et al (1999). anhydrous bovine pancreatic insulin rather than a Zn group derived from a polyatomic compound is trivial compared to the uncertainty arising from using the groups in Table 3 and Eq. (17) to estimate the thermodynamic contributions of the amino acids to the properties of anhydrous bovine pancreatic insulin.…”

Thermophysical properties of aqueous and frozen states of BSA/water/Tris systems

“…In addition, Cornillon (1993) proposed the following heat capacity correlation for pure olvabumin (Mw = 45,000 kg/ kmol): Cp (J/(kg K)) = 1559 + 7.5 T where the temperature T is expressed in • C. Using this value with an additive rule, we obtained Cp = 1910 J/(kg K) for our formulation, instead of 1710 J/(kg K) at 20 • C. For dried olvabumin, Lorenzo et al [35] at 20 • C proposed Cp = 1200 J/(kg K) which confirms the reliability of our determination.…”