Heart Rate Variability and Biological Age: Implications for Health and Gaming

Russoniello, Carmen; Zhirnov, Yevgeniy N.; Pougatchev, Vadim I.; Gribkov, Evgueni N.

doi:10.1089/cyber.2013.1505

Cited by 37 publications

(33 citation statements)

References 28 publications

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“…These researchers measured HRV in the frequency domain and concluded that the 5-minute HRV test was clinically useful as a risk stratification tool 54. Recently, the recording time period of five minutes was used as a “gold standard” in studies to determine the accuracy of HRV derived from photoplethysmography 55,56…”

Section: Discussionmentioning

confidence: 99%

“…Besides inflammation,21,51–53 additional factors associated with HRV or clinical depression need to be considered as possible confounders, such as age,11,15,55,56 sex,11,15,60,61 genetics,62 and comorbidities 11. Another attenuating factor is the administration of medications, such as beta blockers, which are widely used in the treatment of ACS.…”

Section: Discussionmentioning

confidence: 99%

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Heart rate variability measurement and clinical depression in acute coronary syndrome patients: narrative review of recent literature

Harris

Sommargren²,

Stein³

et al. 2014

NDT

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AimWe aimed to explore links between heart rate variability (HRV) and clinical depression in patients with acute coronary syndrome (ACS), through a review of recent clinical research literature.BackgroundPatients with ACS are at risk for both cardiac autonomic dysfunction and clinical depression. Both conditions can negatively impact the ability to recover from an acute physiological insult, such as unstable angina or myocardial infarction, increasing the risk for adverse cardiovascular outcomes. HRV is recognized as a reflection of autonomic function.MethodsA narrative review was undertaken to evaluate state-of-the-art clinical research, using the PubMed database, January 2013. The search terms “heart rate variability” and “depression” were used in conjunction with “acute coronary syndrome”, “unstable angina”, or “myocardial infarction” to find clinical studies published within the past 10 years related to HRV and clinical depression, in patients with an ACS episode. Studies were included if HRV measurement and depression screening were undertaken during an ACS hospitalization or within 2 months of hospital discharge.ResultsNine clinical studies met the inclusion criteria. The studies’ results indicate that there may be a relationship between abnormal HRV and clinical depression when assessed early after an ACS event, offering the possibility that these risk factors play a modest role in patient outcomes.ConclusionWhile a definitive conclusion about the relevance of HRV and clinical depression measurement in ACS patients would be premature, the literature suggests that these measures may provide additional information in risk assessment. Potential avenues for further research are proposed.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Heart rate variability measurement and clinical depression in acute coronary syndrome patients: narrative review of recent literature

Harris

Sommargren²,

Stein³

et al. 2014

NDT

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“…HRV obtained from PPG have been shown to be highly correlated with ECG derived HRV and can be used to assess vagal tone [18]. There are a number of devices using PPG technology that are available to the public e.g.…”

Section: Hrv Using Photoplethysmography (Ppg) Technologymentioning

confidence: 99%

“…Recently PPG technology has been implemented in mobile devices by using the cameras as the optical sensor, making home monitoring of vagal tone very easy and affordable. Also, it has been shown that the maximum variation in heart rate (the largest respiratory sinus arrhythmia, also a measure of HRV) during a 1 min deep breathing test showed a better correlation with age when compared using parameters derived from 5 min HRV recordings [18]. Hence a fairly easy algorithm can be used to determine age-adjusted vagal tone.…”

Section: Hrv Using Photoplethysmography (Ppg) Technologymentioning

confidence: 99%

Can natural ways to stimulate the vagus nerve improve seizure control?

Yuen

Sander

2017

Epilepsy & Behavior

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The vagus nerve (VN) is the longest cranial nerve innervating the neck, thorax and abdomen, with afferent fibres transmitting a range of interoceptive stimuli and efferent fibres to somatic structures and autonomic preganglions. Over the last few decades, electrical stimulation of the VN using implanted devices (VNS) has been developed leading to its approval for the treatment of epilepsy and depression. More recently non-invasive devices to stimulation the VN have been developed. The VN has many functions and the activity that is most amenable to assessment is its effect in controlling the cardiac rhythm. This can be easily assessed by measuring heart rate variability (HRV). Decreased HRV is a result of poorer vagal parasympathetic tone and is associated with a wide range of ill health conditions including a higher risk of early mortality. People with epilepsy, particularly those with poorly controlled seizures have been shown to have impaired parasympathetic tone. So, might natural ways to stimulate the VN, shown to improve parasympathetic tone as indicated by increased HRV, improve seizure control? There are numerous natural ways that have been shown to stimulate the VN, improving HRV and hence parasympathetic tone. These natural ways fall mainly into 3 categories -stress reduction, exercise and nutrition. Though the natural ways to stimulate the VN have been shown to increase HRV, they have not been shown to reduce seizures. The exception is listening to Mozart's music which has been shown to increase parasympathetic tone and decrease seizures. Clearly much more work is required to examine the effect of the various ways to increase HRV on seizure occurrence.

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“…We can actually capture these moments with physiological measurements such as heart rate variability, a robust measure of ANS function. 47,48 Hence, the consumer should be central to game development.…”

Section: Tom Baranowski: If You Are Going To Include a Story What Armentioning

confidence: 99%