Heart rate and blood pressure variability are predictors of target organ damage in arterial hypertension

Marinakis, A.G.; Vyssoulis, Gregory P.; Karpanou, Eva A.; Barbetseas, John; Stavrotheodoros, C.K.; Cokkinos, Dennis V.; Toutouzas, Pavlos

doi:10.1016/s0895-7061(03)00747-7

Cited by 4 publications

(3 citation statements)

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“…electrocardiographic left ventricular hypertrophy (LVH) (Sokolow-Lyon > 38 mm; Cornell >2440 mm x ms) -echocardiographic LVH (left ventricle mass index in men ≥ 126 g/m 2 and in women ≥ 110 g/m 2 ) -carotid wall thickening (IMT > 0.9 mm) or plaque ankle/brachial index <0.9 -slight increase in plasma creatinine males: 115-133 μmol/l (1.3-1.5 mg/dl) -females: 107-124 μmol/l (1.2-1.4 mg/dl) -Low estimated glomerular filtration rate (< 60 ml/min/1.73 m 2 ) or creatinine clearance < 60 ml/min -Microalbuminuria 30-300 mg/24 h or albumin-creatinine ratio: ≥22 (males); or ≥31 (females) mg/g creatinine Since then, other studies proposed home blood pressure to be as reliable as ambulatory monitoring in predicting hypertension-induced target-organ damage, because it is superior to carefully taken office measurements (Viazzi, 2002;Stergiou, 2007). Marinakis et al have demonstrated a relationship between heart rate variability and TOD, thus highlighting its importance in the genesis of subclinical cardiovascular disease (Marinakis, 2003). Recently, inflammation, and in particular tumor necrosis factor-α (TNF-α), has been implied in the cascade leading to TOD in patients with essential hypertension (Navarro-Gonzalez, 2008).…”

Section: Introductionmentioning

confidence: 99%

Coronary Artery Diseases

Yin

Hsiung

2023

Atlas of Perioperative 3D Transesophageal Echocardiography

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In 2000-2005 he was working as lead researcher in hightech companies SQUID AG and MagScan GmbX (Germany). Currently, he is senior staff scientist in the field of medical cybernetics at International Research and Training Center for ITandS of NAS of Ukraine. He combines clinical work with research, focusing on advanced methods for analysis (including pattern recognition) of electrocardiogram , magnetocardiogram , heart rate variability and implementation of such approaches in clinical routine. His research in these areas has been presented at international congresses (ESC, AHA, ACC and many others) and has appeared in academic journals such as PACE, Clinical Cardiology, Annals of Noninvasive Electrocardiology, European Heart Journal, Biophysics etc. He is the author of the book (together with L. Fainzilberg) , devoted to analysis of PrefaceThis book has "wide geography" both literally and figuratively. First of all, this book brings together contributions from around the world, both from post-industrial countries and developing world. This is natural, because coronary artery disease is becoming pandemic worldwide. CAD is the single most frequent cause of death in developed countries, causes about 1 in every 5 deaths.Mortality from cardiovascular disease is predicted to reach 23.4 million in 2030. Moreover, in the developing world, cardiovascular disease tends to affect people at a younger age and thus could negatively affect the workforce and economic productivity. The morbidity, mortality, and socioeconomic importance of CAD make its diagnosis and management fundamental for all practicing physicians. On another hand, the book widely represents "geography" of CAD itself, i.e. many various aspects of its pathophysiology, epidemiology, diagnosis, treatment are touched in this book.Pathophysiologic mechanisms of CAD are well studied in general, but there are some details to be clarified. Oxidative stress is considered as one of important pathogenetic components of the atherosclerosis course, studies of its effect onto the atherosclerotic plaque formation and progression are still lasted. Section "Coronary artery disease: pathophysiology and epidemiology" includes the review "Coronary Artery Disease and Oxidative Stress"concerning this problem.Another chapter in this Section is an epidemiological research demonstrating capabilities of the modern genetic risk factors in improvement of the ability to predict incident CAD beyond that afforded by traditional non genetic risk factors.Section "Coronary artery disease: diagnostic features" begins with the chapter "Magnetocardiography in Unshielded Setting: Heart Electrical Image based on 2-D and 3-D Data in Comparison with Perfusion Image Based on PET Results", devoted to the promising technique of investigation of the cardiac electrical generatormagnetocardiography (MCG). Comparison is drawn of the cardiac imaging on the base of current density distribution maps, obtained by MCG and PET images. Two other articles of this Section are devoted to the different issues of the mo...

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Section: Introductionmentioning

confidence: 99%

Coronary Artery Diseases

Yin

Hsiung

2023

Atlas of Perioperative 3D Transesophageal Echocardiography

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“…Marinakis et al have demonstrated a relationship between heart rate variability and TOD, thus highlighting its importance in the genesis of subclinical cardiovascular disease (Marinakis, 2003). Recently, inflammation, and in particular tumor necrosis factor-α (TNF-α), has been implied in the cascade leading to TOD in patients with essential hypertension (Navarro-Gonzalez, 2008).…”

Section: Introductionmentioning

confidence: 99%

Specific Features of Target Organ Damage in Patients with Arterial Hypertension and Coronary Artery Disease

Şerban¹,

Christodorescu²,

Caraba³

et al. 2012

Coronary Artery Diseases

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“…European guidelines for the management of arterial hypertension from 2007 defined target organ damage by the presence of any of the following: Low estimated glomerular filtration rate (< 60 ml/min/1.73 m 2 ) or creatinine clearance < 60 ml/min -Microalbuminuria 30-300 mg/24 h or albumin-creatinine ratio: ≥22 (males); or ≥31 (females) mg/g creatinine Since then, other studies proposed home blood pressure to be as reliable as ambulatory monitoring in predicting hypertension-induced target-organ damage, because it is superior to carefully taken office measurements (Viazzi, 2002;Stergiou, 2007). Marinakis et al have demonstrated a relationship between heart rate variability and TOD, thus highlighting its importance in the genesis of subclinical cardiovascular disease (Marinakis, 2003). Recently, inflammation, and in particular tumor necrosis factor-α (TNF-α), has been implied in the cascade leading to TOD in patients with essential hypertension (Navarro-Gonzalez, 2008).…”

Section: Introductionmentioning

confidence: 99%

Coronary Artery Diseases

Dymarkowski

Bogaert

2011

Clinical Cardiac MRI

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he was working as lead researcher in hightech companies SQUID AG and MagScan GmbX (Germany). Currently, he is senior staff scientist in the field of medical cybernetics at International Research and Training Center for ITandS of NAS of Ukraine. He combines clinical work with research, focusing on advanced methods for analysis (including pattern recognition) of electrocardiogram , magnetocardiogram , heart rate variability and implementation of such approaches in clinical routine. His research in these areas has been presented at international congresses (ESC, AHA, ACC and many others) and has appeared in academic journals such as PACE, Clinical Cardiology, Annals of Noninvasive Electrocardiology, European Heart Journal, Biophysics etc. He is the author of the book (together with L. Fainzilberg) , devoted to analysis of ECG in phase space. Dr Nataliia Sydorova was born in Kiev, Ukraine, in 1975. She got University Degree in General Medicine (1999) and earned her PhD in Cardiology (2003) at the Bogomolets National Medical University. She has been working as a cardiologist at Cardiological Clinic of Main Military Clinical Hospital of Ministry of Defence of Ukraine (Kiev) till 2001, and then -at Department of Military Common Practice and Family Medicine of the Ukrainian Military Medical Academy (Kiev). Her current position at this department is Associated Professor. In addition Dr. Sydorova was a Deputy Editor of the 'Journal of the American College of Cardiology. Ukrainian edition' from 2008 till 2010. At the present time she is a Deputy Editor of the 'Therapia. Ukrainian Medical Bulletin' journal (from 2010). She has got 12 patents for an invention and ca. 130 scientific publications.

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Heart rate and blood pressure variability are predictors of target organ damage in arterial hypertension

Cited by 4 publications

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Coronary Artery Diseases

Coronary Artery Diseases

Specific Features of Target Organ Damage in Patients with Arterial Hypertension and Coronary Artery Disease

Coronary Artery Diseases

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