Heart Failure with Preserved Ejection Fraction (“Diastolic Heart Failure”)

Oktay, Ahmet Afsin; Shah, Sanjiv J.

doi:10.5005/jp/books/12817_12

Cited by 2 publications

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“…However, there is a lack of development of drugs targeting HF with preserved ejection fraction (HFpEF), and many have failed in clinical trials. [5–7]…”

Section: Association Analysis Of Long-term Covid-19 and Hfmentioning

confidence: 99%

A comprehensive review on the association and prevention of long-term COVID-induced heart failure: A review

Ren,

2024

Medicine

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The coronavirus disease 2019 (COVID-19) disease caused by the severe acute respiratory syndrome coronavirus 2 has had a widespread global impact. In addition to the main respiratory symptoms, research has found significant effects of this virus on the cardiovascular system. This article comprehensively explores the phenomenon of “long-term COVID-19” or postacute sequelae of severe acute respiratory syndrome coronavirus 2 infection, wherein some recovered patients continue to experience long-term health issues after the resolution of acute illness. We delve into the potential reasons behind these symptoms, including increased risk of heart disease, myocardial injury, abnormal inflammatory responses, thrombosis formation, and immune system dysfunction, among others. Furthermore, this paper highlights the potential association between long-term COVID-19 and HF (heart failure), and proposes corresponding preventive strategies. To address this, we advocate for a collaborative approach involving interdisciplinary teams for treatment and management.

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“…However, there is a lack of development of drugs targeting HF with preserved ejection fraction (HFpEF), and many have failed in clinical trials. [5–7]…”

Section: Association Analysis Of Long-term Covid-19 and Hfmentioning

confidence: 99%

A comprehensive review on the association and prevention of long-term COVID-induced heart failure: A review

Ren,

2024

Medicine

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“…С введением рекомендаций по измерениям артериальной жесткости в 2006 г. в европейском консенсусном документе [24], публикацией международных эталонных стандартов в 2010 г. [33] и научного заявления Американской кардиологической ассоциации (AHA) об измерениях артериальной жесткости в США [34] теперь доступны улучшенные рекомендации, обеспечивающие бóльшее единообразие в клинических исследованиях [18].…”

Section: оригинальные статьи § обсуждениеunclassified

“…Предполагается, что параметры, оценивающие жесткость сосудистой стенки, обеспечивают новую и клинически значимую информацию, кроме информации, предоставленной стандартными ФР [16,17]. В настоящее время эксперты считают, что сосудистая жесткость является одним из самых ранних обнаруживаемых патологических изменений стенки артерии и является сильным предиктором будущих сердечно-сосудистых осложнений и смертности [18]. По данным согласованного мнения российских экспертов по оценке артериальной жесткости в клинической практике, повышенная артериальная жесткость может наблюдаться при таких состояниях, как старение, менопауза, недостаточная физическая активность, семейный анамнез АГ, СД 1 и 2 типа, ИМ, метаболический синдром, ожирение, курение, АГ, нарушение толерантности к глюкозе, высокий уровень С-реактивного белка, гиперхолестеринемия, ИБС, ХСН, инсульт, хроническая болезнь почек (ХБП) [19].…”

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“…Технологии, используемые для оценки сосудистой жесткости, делятся на инвазивные и неинвазивные, такие как осциллометрия, тонометрия, ультразвуковое и магнитно-резонансное исследование. Они существенно различаются по стоимости, времени, требуемому для измерения, и технической экспертизе, необходимой для проведения измерений, но все рассматриваются как рекомендуемые методы оценки параметров жесткости сосудистой стенки [18]. Большинство показателей сосудистой жесткости с учетом их вариабельности можно измерить с помощью отечественного регистратора АД «BPLab» (ООО «Петр Телегин», Россия) в комплексе с программой Vasotens [20,21].…”

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Daily variability of arterial stiffness of patients with arterial hypertension depending on the category of cardiovascular risk

Tarlovskaya

Merezhanova

2018

Kardiologiia

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Purpose. The study of the daily variability of arterial stiffness indicators, depending on the category of cardiovascular risk. Materials and methods. The study consistently included patients with essential hypertension who were admitted to the cardiology department of the Volga district medical center from November 1, 2015 to October 1, 2017. The study involved 134 patients with an average age of 52±1 years. Depending on the category of total cardiovascular risk, the patients were divided into 3 groups from I (lowest risk) to III (highest risk). The analysis was carried out on ABPM for 12–14 days (BPLab system of “Peter Telegin” firm). Determined: glomerular filtration rate (GFR), the thickness of the intima-media of the common carotid arteries, analysis of the lipid spectrum. For statistical analysis of clinical and instrumental data, a T-criterion for independent samples was used and an ANOVA analysis was performed. A correlation analysis was performed. Results. Patients of group III had the highest level of av. SBP (рI–III=0.010; pII–III=0.020) and mean pulse BP (PBP) (рI–III=0.002; pII–III=0.002), also more unfavorable the indicators cALALx (pI–II=0.025; рI–III=0.004), varAlx (рI–III=0.004) and av. ASI (рI–III=0.034). When comparing the data of patients of groups II and III, adjusted for gender and age, it was found that statistically significant differences between the groups of varPAD (pII–III=0.008), AASI (рI–III=0.043), varAlx (pII–III=0.049), as well as a pronounced tendency for varASI (pII–III=0.050). Markers of target organ damage (TIM, LVML, GFR) were more pronounced in the high-risk group. As the risk group increased, the level of HDL decreased (рI–III=0.002; pII–IIII=0.0001), the level of TG increased (рI–III=0.007; pII–III=0.009) and the CA (рI–III=0.015). The total cholesterol level was lower in patients of group III compared to group II (pII–III=0.004). Statistically signifi nt relationships of arterial wall stiffness indicators with age were found: crAlx (0.467, p<0.001), varAlx (0.272, p<0.01), cpASI (0.227, p<0.01), varASI (0.407, p<0.001). In addition, women showed significant correlations of medium and high strength between age and mean values of mean SPD (r = 0.490, p<0.05), varPAD (r=0.540, p<0.05), avAS (r=0.460, p<0.05) and varASI (r=0.620, p<0.05). VarASI and WedSASI were most closely associated with the level of SRSAD and SRPAD. Only cASI was associated with GFR, and only varASI was associated with the parameters of the lipid spectrum (HSLPVP, TG, KA and LVMI. Conclusion. The most statistically significant dynamics was observed when evaluating varASI, which varied in the sequence I gr. <II gr. < III gr. Corrected by sex and age, the analysis showed a greater variability in arterial stiffness in high-risk patients.

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Heart Failure with Preserved Ejection Fraction (“Diastolic Heart Failure”)

Cited by 2 publications

References 0 publications

A comprehensive review on the association and prevention of long-term COVID-induced heart failure: A review

A comprehensive review on the association and prevention of long-term COVID-induced heart failure: A review

Daily variability of arterial stiffness of patients with arterial hypertension depending on the category of cardiovascular risk

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