Hearing and vestibular loss in <i>Streptococcus suis</i> infection from swine and traditional raw pork exposure in northern Thailand

Navacharoen, Niramon; Chantharochavong, V; Hanprasertpong, Charuk; Kangsanarak, Jaran; Lekagul, S

doi:10.1017/s0022215109004939

Cited by 40 publications

(60 citation statements)

References 11 publications

(23 reference statements)

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“…The main portal of entry for the organism is via the oral or alimentary mucosa. Hearing and vestibular impairment are the main sequelae in patients with S. suis meningitis [10]. The number of patients with psychogenic vertigo in this study and the other studies in Thailand were substantially lower (0.1-2.6%) than previously reported (5.1-11.5%) [1,7,8].…”

Section: Discussioncontrasting

confidence: 65%

Causes and time-course of vertigo in an ear, nose, and throat clinic

Isaradisaikul

Navacharoen

Hanprasertpong

et al. 2010

Eur Arch Otorhinolaryngol

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The purpose of this study is to review etiologies and identify the time-course of vertigo presenting in an ear, nose, and throat clinic, and serve as a reference guide for other clinics. The study includes retrospective chart review in a tertiary care, university hospital. The patient data with reported ICD-10 codes as causes of vertigo between April 2005 and December 2007 were extracted from the database. At each visit, the main diagnosis as to etiology, characteristics of the vertigo, its time-course, and patient demographic data were recorded. Of 547 cases, 17 diagnoses were made in 73.9%. Diagnostic categories included peripheral vertigo 72.9%, central vertigo 0.8%, psychogenic cause 0.2%, and unknown 26.1%. Common causes of vertigo were benign paroxysmal positional vertigo (BPPV) 52.5%, Meniere's disease 14.6%, and sudden idiopathic hearing loss 2.9%. Less common diagnoses were benign paroxysmal vertigo of childhood 0.7%, labyrinthitis 0.7%, and vestibular schwannoma 0.3%. Rare conditions were delayed endolymphatic hydrops, Ramsey Hunt syndrome, otosyphilis, vestibular neuritis, temporal bone fracture, post-concussion syndrome, cerebellar infarction, epilepsy, cervical vertigo, Streptococcus suis meningitis, and psychogenic vertigo. Ninety-nine cases who reported remission of vertigo during the study period had median onset of the remission at 4 weeks. In the ear, nose, and throat clinic at Chiang Mai University, a tertiary university hospital, peripheral vestibular disorders were the main etiology of vertigo. The three most common causes were BPPV, Meniere's disease, and sudden idiopathic hearing loss. Half of the cases who returned for follow up had remitted symptoms within 4 weeks.

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Section: Discussioncontrasting

confidence: 65%

Causes and time-course of vertigo in an ear, nose, and throat clinic

Isaradisaikul

Navacharoen

Hanprasertpong

et al. 2010

Eur Arch Otorhinolaryngol

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“…Eight of 25 large studies reporting hearing loss indicated whether hearing loss was permanent after hospital discharge. Only 4 described their follow-up processes; follow-up time ranged from 2 months to 30 months ( 4 , 8 , 28 , 31 ). On the basis of these limited data, we estimated a comparatively low median rate of recovery from hearing loss of 5.0% (range 0%–52.3%) and the pooled rate of 15.4% (95% CI 5.3%–37.3% (Table 4).…”

Section: Resultsmentioning

confidence: 99%

“…It is potentially preventable ( 3 , 6 ). Epidemiology of the infection differs between Western and Asian regions ( 7 ), and the role of high-risk eating habits (i.e., ingesting raw or undercooked pig parts, including pig blood, organs, and meat) in some Asian communities recently has been recognized ( 6 , 8 , 9 ). Rates of S. suis infection are low in the general populations of Europe and North America, and cases are concentrated among occupationally exposed groups, including abattoir workers, butchers, and pig breeders ( 10 , 11 ).…”

mentioning

confidence: 99%

Epidemiology, Clinical Manifestations, and Outcomes ofStreptococcus suisInfection in Humans

Huong¹,

Ha²,

Huy³

et al. 2014

Emerg. Infect. Dis.

202

277

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“…This case fatality rate is equivalent to that recorded previously in Thailand [4], [11], [12]. To exclude the possibility that human cases of S. suis infection in residents of Phayao Province were detected in hospitals in the surrounding three provinces of Chiang Rai, Lampang, and Nan, we investigated all human cases in these provinces through the hospital network surveillance system for S. suis infection organized by the Thai NIH in 2010 [17].…”

Section: Discussionmentioning

confidence: 96%

“…This province is located close to the border with the Lao People's Democratic Republic, and the population of this province was 486,304 in 2010 [7]. Although previous studies reported that human cases of S. suis infection are associated with the recent consumption of raw pork products in northern Thailand and Vietnam [2]–[6], [8]–[11], the annual incidence rate of this disease in this region remains unknown.…”

Section: Introductionmentioning

confidence: 99%

Population-Based Study of Streptococcus suis Infection in Humans in Phayao Province in Northern Thailand

Takeuchi

Kerdsin

Pienpringam³

et al. 2012

PLoS ONE

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Background Streptococcus suis infection in humans has received increasing worldwide recognition.Methods and FindingsA prospective study of S. suis infection in humans was conducted in Phayao Province in northern Thailand to determine the incidence and the risk behaviors of the disease in this region in 2010. Thirty-one cases were confirmed. The case fatality rate was 16.1%, and the estimated incidence rate was 6.2 per 100,000 in the general population. The peak incidence occurred in May. The median age of the patients was 53 years and 64.5% were men. Consumption of raw pork products was confirmed in 22 cases and the median incubation period (range) was 2 days (0–11) after consumption of raw pork products. Isolates from 31 patients were confirmed as serotype 2 in 23 patients (74.2%) and serotype 14 in eight patients (25.8%). The major sequence types (STs) were ST1 (n = 20) for serotype 2 and ST105 (n = 8) for serotype 14. The epidemiological analysis suggested three possible clusters, which included 17 cases. In the largest possible cluster of 10 cases in Chiang Kham and its neighboring districts in May, the source of infection in four cases was identified as a raw pork dish served at the same restaurant in this district. Microbiological analysis confirmed that three of four cases associated with consumption of raw pork at this restaurant were attributable to an identical strain of serotype 2 with ST1 and pulsotype A2.ConclusionsOur data suggest a high incidence rate of S. suis infection in the general population in Phayao Province in 2010 and confirm a cluster of three cases in 31 human cases. Food safety control should be strengthened especially for raw pork products in northern Thailand.

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Hearing and vestibular loss in Streptococcus suis infection from swine and traditional raw pork exposure in northern Thailand

Abstract: Permanent hearing loss and vestibular impairment occur frequently in persons surviving meningitis caused by Streptococcus suis.

Cited by 40 publications

References 11 publications

Causes and time-course of vertigo in an ear, nose, and throat clinic

Causes and time-course of vertigo in an ear, nose, and throat clinic

Epidemiology, Clinical Manifestations, and Outcomes ofStreptococcus suisInfection in Humans

Population-Based Study of Streptococcus suis Infection in Humans in Phayao Province in Northern Thailand

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