Healthcare Workers’ Knowledge and Resource Availability for Care of Sickle Cell Disease in Dar es Salaam, Tanzania

Jonathan, Agnes; Tutuba, Hilda; Lloyd, William E.; Ndunguru, Joyce; Makani, Julie; Ruggajo, Paschal; Minja, Irene Kida; Balandya, Emmanuel

doi:10.3389/fgene.2021.773207

Cited by 11 publications

(9 citation statements)

References 23 publications

(30 reference statements)

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“…Comprehensive management of SCD requires effective healthcare systems and necessitates healthcare professionals to have appropriate knowledge of the disease. The current study noted that the treatment of SCD was largely by GP practice compared to specialized care (40). Considering the limited number of specialist physicians such as hematologists and pediatricians in the region, upskilling community practice physicians such as GPs and internal medicine doctors could help strengthen the care delivery for SCD patients.…”

Section: Discussionmentioning

confidence: 90%

Evaluation of Treatment Patterns, Healthcare Resource Utilization and Cost of Illness for Sickle Cell Disease in Ghana: A Private Medical Insurance Claims Database Study

Marfo

Dei‐Adomakoh

Segbefia

et al. 2022

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Background Sickle cell disease (SCD) is a major public health concern in sub-Saharan Africa, accounting for nearly 75% of the global disease burden. The current analysis evaluated patient characteristics, treatment patterns, healthcare resource utilization and associated costs in patients with SCD, based on a Private Medical Insurance Database in Ghana. Methods This retrospective longitudinal cohort study was conducted using a e-claims database from Ghana (01 January 2015 to 31 March 2021). Patients were stratified by age (0 month to < 2 years, ≥ 2 years to ˂6 years, ≥ 6 years to < 12 years, ≥ 12 years to < 16 years; ≥16 years) and vaso-occlusive crisis (VOC) (< 1, ≥ 1 to < 3, and ≥ 3 per year). Results The study included 2,863 patients (mean age: 20.1 years; Min age: 0; Max age: 83; females 56.1%). Overall, 52.2% (n = 1,495) of SCD patients were ≥ 16 years and 17.0% (n = 486) were in the ≥ 2 to ˂6-years age group. The majority of patients aged ≥ 16 years (62.5%) in the database did not have reported VOC episodes while 35.9% of patients had 1 to 3 VOC episodes per year during the follow-up period. Consultation-based prevalence of SCD was 0.5% [95% confidence interval (CI): 0%-1.3%] − 1.4% [CI: 0.6%-2.2%]. Malaria, upper respiratory tract infection (URTI) and sepsis were the common complications of SCD. Analgesics were the most frequently prescribed medications followed by anti-infectives, hematinics, and antimalarials. SCD patients had median cost incurred for consultation/hospital services of $11.3 (Interquartile range [IQR] $6.2 - $27.2). For patients with VOC, maximum median cost was incurred for medications ($10.9 [IQR $5.0-$32.6]). Overall median healthcare cost was highest for individuals with ≥ 3 VOCs per year ($166.8 [IQR $70.3-$223.5]). Conclusion SCD imposes a significant healthcare burden in Ghana, especially in patients with VOC. There is a need for reimbursed treatment options that could reduce the long-term burden associated with SCD and VOC.

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Section: Discussionmentioning

confidence: 90%

Evaluation of Treatment Patterns, Healthcare Resource Utilization and Cost of Illness for Sickle Cell Disease in Ghana: A Private Medical Insurance Claims Database Study

Marfo

Dei‐Adomakoh

Segbefia

et al. 2022

Preprint

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“…Management of SCD has improved significantly, especially in developed countries [ 1 ]. In middle- and lower-income countries, where the burden of SCD is high, the management of SCD is still suboptimal including lack of awareness and proper knowledge, inadequate screening, diagnosis and treatment [ 6 ]. In these settings, SCD diagnosis is often made for the first time when there are already complications due to the disease.…”

Section: Introductionmentioning

confidence: 99%

“…In these settings, SCD diagnosis is often made for the first time when there are already complications due to the disease. Early diagnosis and management will help to reduce complications, morbidity and mortality due to SCD [ 1 , 6 , 7 ].…”

Section: Introductionmentioning

confidence: 99%

The efficacy of maternal health education and maternal screening on knowledge and the uptake of infant screening for sickle cell disease in Dar-Es-Salaam, Tanzania; a quasi experimental study

et al. 2023

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Background Globally, Sickle cell disease (SCD) is one of the most common genetic disease with high childhood mortality. Early identification of babies with SCD through newborn screening (NBS) and linking them to care are among the recommended interventions. The purpose of this study was to assess the efficacy of maternal health education and maternal screening for SCD on knowledge and the uptake of infant screening for SCD among mother-infant pairs attending antenatal clinics at Government health facilities in Dar-es-salaam, Tanzania. Methods This study was a pre-test post-test, quasi-experimental which involved pregnant women attending antenatal clinics at three hospitals; Mbagala hospital, Sinza hospital and Buguruni health center in Dar Es Salaam. A structured questionnaire was used in data collection. Knowledge on SCD was assessed for all participants before and after two sessions of health education. Participants in Mbagala and Buguruni were also screened for SCD using Sickle SCAN point-of-care test (BioMedomics Inc, USA). The efficacy for health education intervention was computed as the post-intervention minus baseline knowledge score. For proportions, a two-sample z-test was used. Univariate and multivariate logistic regression were used to analyze the efficacy of health education intervention and also predictors of infant diagnosis. Results For two sessions of health education intervention, a total of 467 pregnant women completed the sessions. During antenatal visits, a total of 218 were screened for SCD. The proportion of participants with good knowledge of SCD had significantly increased to 85.9% from 12.4% at baseline following the education intervention. In multivariate analysis, sharing the received education on SCD was an independent predictor of the efficacy of health education intervention. Maternal occupation, maternal SCD status as well as sharing the received education on SCD were independent predictors of the uptake of SCD infant diagnosis. Conclusion This study has demonstrated that maternal health education and maternal screening for SCD are feasible and efficacious interventions in raising knowledge and improving the uptake of infant diagnosis for SCD. These interventions are strongly recommended to be included in the comprehensive care package for pregnant women attending antenatal clinics, particularly in areas with a high burden of SCD.

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“…The stigma may be linked to inadequate knowledge. 10 It may worsen when PLwSCD transition from paediatric to adult care 11 and may be associated with delays in seeking care. 12 Unaffordable healthcare costs is an issue in many settings.…”

mentioning

confidence: 99%

Needs assessment in adults and parents of children living with sickle cell disease in Jamaica

et al. 2023

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Healthcare Workers’ Knowledge and Resource Availability for Care of Sickle Cell Disease in Dar es Salaam, Tanzania

Cited by 11 publications

References 23 publications

Evaluation of Treatment Patterns, Healthcare Resource Utilization and Cost of Illness for Sickle Cell Disease in Ghana: A Private Medical Insurance Claims Database Study

Evaluation of Treatment Patterns, Healthcare Resource Utilization and Cost of Illness for Sickle Cell Disease in Ghana: A Private Medical Insurance Claims Database Study

The efficacy of maternal health education and maternal screening on knowledge and the uptake of infant screening for sickle cell disease in Dar-Es-Salaam, Tanzania; a quasi experimental study

Needs assessment in adults and parents of children living with sickle cell disease in Jamaica

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