The efficacy of maternal health education and maternal screening on knowledge and the uptake of infant screening for sickle cell disease in Dar-Es-Salaam, Tanzania; a quasi experimental study

Abstract

Background Globally, Sickle cell disease (SCD) is one of the most common genetic disease with high childhood mortality. Early identification of babies with SCD through newborn screening (NBS) and linking them to care are among the recommended interventions. The purpose of this study was to assess the efficacy of maternal health education and maternal screening for SCD on knowledge and the uptake of infant screening for SCD among mother-infant pairs attending antenatal clinics at Government health facilities in Dar-es-salaam, Tanzania. Methods This study was a pre-test post-test, quasi-experimental which involved pregnant women attending antenatal clinics at three hospitals; Mbagala hospital, Sinza hospital and Buguruni health center in Dar Es Salaam. A structured questionnaire was used in data collection. Knowledge on SCD was assessed for all participants before and after two sessions of health education. Participants in Mbagala and Buguruni were also screened for SCD using Sickle SCAN point-of-care test (BioMedomics Inc, USA). The efficacy for health education intervention was computed as the post-intervention minus baseline knowledge score. For proportions, a two-sample z-test was used. Univariate and multivariate logistic regression were used to analyze the efficacy of health education intervention and also predictors of infant diagnosis. Results For two sessions of health education intervention, a total of 467 pregnant women completed the sessions. During antenatal visits, a total of 218 were screened for SCD. The proportion of participants with good knowledge of SCD had significantly increased to 85.9% from 12.4% at baseline following the education intervention. In multivariate analysis, sharing the received education on SCD was an independent predictor of the efficacy of health education intervention. Maternal occupation, maternal SCD status as well as sharing the received education on SCD were independent predictors of the uptake of SCD infant diagnosis. Conclusion This study has demonstrated that maternal health education and maternal screening for SCD are feasible and efficacious interventions in raising knowledge and improving the uptake of infant diagnosis for SCD. These interventions are strongly recommended to be included in the comprehensive care package for pregnant women attending antenatal clinics, particularly in areas with a high burden of SCD.

Current Status of Newborn Bloodspot Screening Worldwide 2024: A Comprehensive Review of Recent Activities (2020–2023)

“…A 2022 report of a study of POC tests (HemoTypeSC TM and SickleSCAN ® ) showed reliability of either versus IEF, and both were found to be acceptable for screening [ 1577 ]. A 2023 report of a study at three hospitals in Dar-Es-Salaam reported that maternal health education and maternal screening for SCD were feasible and efficacious interventions to increase the knowledge and uptake of NBS, and these interventions were strongly recommended for inclusion in comprehensive care packages for pregnant women attending antenatal clinics [ 1578 ].…”

Pengaruh Pendidikan Kesehatan terhadap Pengetahuan dan Sikap Siswa SMK dalam Menghadapi Bencana Banjir

“…Pada penelitian ini, pendidikan kesehatan yang diberikan dalam bentuk ceramah, diskusi dan demonstrasi dengan menggunakan media slide power point serta leaflet tentang upaya pencegahan dan cara menghadapi banjir. Pendidikan Kesehatan dapat bermanfaat untuk mendorong para responden yang mendapatkan pendidikan kesehatan untuk berbagi pengetahuan dengan orang lain karena hal ini meningkatkan pengetahuan pribadi mereka (Tutuba et al, 2023). Di sisi lain, pendidikan kesehatan adalah suatu cara untuk memberikan informasi, pengetahuan dan pemahaman tentang kesehatan untuk merubah pola pikir individu atau masyarakat menjadi tahu dan merubah perilaku hidup ke arah yang lebih baik untuk menjaga kualitas hidupnya (Taviyanda;, Richard;, & Rimawati, 2022).…”

“…Terjadi juga peningkatan secara signifikan untuk persentase jawaban yang benar pada post test setelah responden diberikan booklet tentang informasi demam berdarah (p<0,05) (AhbiRami & Zuharah, 2020). Literatur ini sesuai dengan literatur yang lain juga bahwa pengetahuan meningkat ketika populasi studi disediakan materi pendidikan kesehatan (Tutuba et al, 2023). Program pendidikan kesehatan secara signifikan meningkatkan pengetahuan dan praktik tentang banjir di daerah tergenang dan pengetahuan hanya di daerah tidak tergenang (P<0,05) (AhbiRami & Zuharah, 2020).…”