Health‐related quality of life and glycaemic control in patients with Type 2 diabetes mellitus in Singapore

Shim, Yoo-Jin; Lee, J.; Toh, Mphs; Tang, Wen-Lu; Ko, Yu

doi:10.1111/j.1464-5491.2012.03689.x

Cited by 89 publications

(103 citation statements)

References 24 publications

(48 reference statements)

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“…These results are consistent with the previous studies [21,25]. The presence of diabetes does not directly lead to pain; however, related complications and treatments such as peripheral neuropathies, delayed wound healing, and insulin injections can cause the pain and discomfort.…”

Section: Discussionsupporting

confidence: 83%

“…This finding is congruent with the previous studies which reported that higher HbA1c was associated with a lower EQ-5D score [25,35]. Having higher levels of HbA1c can contribute to the low HRQoL by either predisposing the patients to a higher risk of complications or imparting anxiety to them about the failure of glycemic control.…”

Section: Butt Et Alsupporting

confidence: 83%

“…Previously, many studies have reported the negative impact of diabetes on the mental health of the patients [11,25,29]. Poor psychological well-being of the diabetes patients can stem from the constant worry about the progressive nature of the disease and development of complications.…”

Section: Butt Et Almentioning

confidence: 99%

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Health-Related Quality of Life in Poorly Controlled Type 2 Diabetes Patients - Association of Patients’ Characteristics With Eq-5d Domains, Mean Eq-5d Scores, and Visaul Analog Scale Score

Butt¹,

Ali²,

Makmor‐Bakry³

2018

Asian J Pharm Clin Res

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Objective: High prevalence of diabetes mellitus in Malaysia demands the appropriate interventions to alleviate or postpone its burden on patients' health-related quality of life (HRQoL). The studies which provide useful knowledge about the components of such interventions are important. The aim of this study was to describe how demographic and clinical characteristics of diabetes patients influence their HRQoL using EQ-5D. Methods:This study used the baseline data of a randomized controlled study carried out to examine the impact of a pharmacist intervention on poorly controlled diabetes patients. A generic HRQoL tool EQ-5D was used to report the data. Logistic regression was used to identify the predictors of problems in individual EQ-5D domains, and ANCOVA was undertaken to examine the effect of patients' characteristic on EQ-5D mean scores and visual analog scale (VAS) mean scores.Results: Pain discomfort was reported to be significantly predicted by high HbA1c levels. Increasing age (OR =1.04; CI 1.01, 1.16) and increasing body mass index (OR = 1.15; CI 1.01, 1.30) were significant predictors of reduced mobility. The presence of complications (OR = 8.03; CI 1.34-48.02) and (5-10 years) diabetes duration predicted the reduced score in anxiety domain (OR = 7.05; CI 1.03, 48.04). Problems in usual activities were significantly predicted by age (OR = 1.4; CI 1.01, 1.18). Self-care was not affected by any of the model covariates. Mean EQ-5D score was (0.89; CI 0.85, 0.92) significantly predicted by HbA1c values (p=0.04). Mean VAS score (70.54) was significantly lower in the group receiving insulin (69.46; CI 73.74, 84.02) than the oral diabetes medication (78.88; CI 64.94, 73.98) (p=0.009). Conclusion:Patients' characteristics were significantly associated with the HRQoL in type 2 diabetes. There was a significant and inverse association of HRQoL with medication group (insulin use), high HbA1c, obesity, and presence of complications.

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Section: Discussionsupporting

confidence: 83%

Section: Butt Et Alsupporting

confidence: 83%

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Health-Related Quality of Life in Poorly Controlled Type 2 Diabetes Patients - Association of Patients’ Characteristics With Eq-5d Domains, Mean Eq-5d Scores, and Visaul Analog Scale Score

Butt¹,

Ali²,

Makmor‐Bakry³

2018

Asian J Pharm Clin Res

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“…Of the six studies that composed the final sample, five (83,3%) (18)(19)(20)(21)(22) were found in MEDLINE and one (16,7%) (23) in CINAHL. It is observed in Chart 2 that no study had agreement with all items in the STROBE.…”

Section: Resultsmentioning

confidence: 99%

“…Two studies (19,21) were performed in the United States, one in Thailand (18) , one in Singapure (23) , one in Mexico (22) and another one in Netherlands (20) . The surveys were conducted between 1998 and 2009 and published from 2004 to 2012.…”

Section: Resultsmentioning

confidence: 99%

The influence of quality of life in treatment adherence of diabetic patients: a systematic review

Gusmai

Novato

Nogueira

2015

Rev. esc. enferm. USP

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Objective:To verify the influence of quality of life in treatment adherence of patients with diabetes mellitus. Method: Systematic review of the literature using the databases MEDLINE, CINAHL, Scopus, LILACS, SciELO and Web of Science with studies published between 2003 and 2014 in English, Portuguese or Spanish. Results: Six studies were included in the review, three were identified as having better quality of life scores, being related to better adherence to diabetes treatment measured by glycated hemoglobin or characteristics related to diet, exercise, use of medication and foot care. No association was found between quality of life and adherence in two investigations and a study found a negative association between these variables. Conclusion: There is causal relationship between quality of life and adherence with diabetes treatment. It is suggested that psychosocial aspects of patients should be considered by health professionals in the search for better clinical outcomes in diabetes care. The influence of quality of life in treatment adherence of diabetic patients: a systematic review * A influência da qualidade de vida na adesão ao tratamento do paciente diabético: revisão sistemática La influencia de la calidad de vida en la adhesión al tratamiento del paciente diabético: revisión sistemática DESCRIPTORS

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Minimally important difference and predictors of change in quality of life in type 2 diabetes: A community‐based survey in China

Jin

Liu

Gerstein

et al. 2018

Diabetes Metabolism Res

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Health‐related quality of life and glycaemic control in patients with Type 2 diabetes mellitus in Singapore

Cited by 89 publications

References 24 publications

Health-Related Quality of Life in Poorly Controlled Type 2 Diabetes Patients - Association of Patients’ Characteristics With Eq-5d Domains, Mean Eq-5d Scores, and Visaul Analog Scale Score

Health-Related Quality of Life in Poorly Controlled Type 2 Diabetes Patients - Association of Patients’ Characteristics With Eq-5d Domains, Mean Eq-5d Scores, and Visaul Analog Scale Score

The influence of quality of life in treatment adherence of diabetic patients: a systematic review

Minimally important difference and predictors of change in quality of life in type 2 diabetes: A community‐based survey in China

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