Health Related Quality of Life of Rosacea Patients in China Assessed by Dermatology Life Quality Index and Willingness to Pay

Abstract

Purpose Rosacea is a chronic inflammatory dermatosis mainly involving facial skin, leading to physical and emotional problems, which greatly affect the quality of life (QoL) of patients. Dermatology Life Quality Index (DLQI) and willingness to pay (WTP) are well-established instruments assessing the health-related quality of life (HRQoL), while very few studies have been focused on this topic about rosacea in China. The present study investigated HRQoL in Chinese rosacea patients. Patients and Methods This cross-sectional study was conducted on 973 patients with rosacea. Sociodemographic data, clinical features and DLQI were collected, and WTP was assessed by three standardized items. Multivariable logistic analysis was performed to investigate independent factors influencing QoL. Results A total of 921 questionnaires were accomplished by participants. The mean DLQI score was 11.6 (median 11). Patients were willing to pay an average of € 896.2 (median € 368.1) for complete cure. 33.3% would like to pay more than 20% of their monthly income to achieve sustainable control. There were positive correlations between WTP with DLQI ( P < 0.05). DLQI could be independently impacted by age (21–30 and 31–40 relative to > 50, OR = 3.242 and 3.617, respectively), the occupational requirement of appearance (high, OR = 4.410), disease duration (< 2 years, OR = 1.582), edema (OR = 1.844) and severity of flushing, burning, stinging and pruritus (severe, OR = 2.003, 1.981, 2.491, 2.249, respectively). There were no significant associations between WTP and most of the clinical factors. Conclusion The QoL was greatly impaired and should not be ignored among rosacea patients in China. Patients aged 21–40y, having occupational requirement of appearance, with the disease duration less than 2 years, and suffering severe flushing and related sensitive symptoms were more likely to have severe or very severe limitation of QoL.

Psychological Burden and Willingness to Pay Among Korean Rosacea Patients and Their Association With Rosacea Phenotype and Severity: A Multi-Center Cross-Sectional Study

“…A recent study by Huang et al . 24 reported that the WTP for controlling rosacea among Chinese patients was $66, slightly lower than the findings in this study.…”

Quality of life measurement in rosacea. Position statement of the European Academy of Dermatology and Venereology Task Forces on Quality of Life and Patient Oriented Outcomes and Acne, Rosacea and Hidradenitis Suppurativa

“…From the 207 articles identified in the literature search, 139 were excluded based on the exclusion criteria, leaving 68 publications 20–87 for the further analysis.…”

“…Another generic HRQoL instrument EuroQoL (EQ)‐5D 55,67 and its modifications EQ‐5D‐3L 76 and EQ‐5D‐visual analogue scale 77 were also used to assess quimp in rosacea. The dermatology‐specific Dermatology Life Quality Index (DLQI) was used for quimp assessment in 45 studies on rosacea 20–23,25,28–30,32,34,35,37,40–42,46,48–57,60,62–69,72–74,77,78,80,82,83,86,87 . Data on the DLQI scores from included articles is given in Figure 1.…”

“…Before (Italia) 87 Lockdown mask users. After (Italia) 87 Before treatment (Israel) 54 Online survey (International) 39 Survey (Germany) 63 Survey (Germany) 52 Before treatment (Germany) 50 Online survey (Germany) 49 Treatment group (Germany) 21 Placebo group (Germany) 21 Online survey (Denmark) 35 Outpatients (China) 74 Before treatment in study group (China) 69 Before treatment in control group (China) 69 Outpatients (China) 68 Rosacea patients with anxiety (China) 66 Rosacea patients with depression (China) 66 Rosacea patients without anxiety (China) 66 Rosacea patients without depression (China) 66 Online survey (China) 60 Outpatients and online survey (China) 53 Before treatment (China) 51 Before treatment (China) 20 Median DLQI…”

A Cross-Sectional Study on the Relationship Between Rosacea Severity and Quality of Life or Psychological State

“…A variety of studies have shown an increased risk of anxiety and depression and impaired QOL in patients with rosacea. [20][21][22][23][24] The clinical features are heterogeneous, so the burden of the disease it causes may vary. However, the complex relationship between rosacea severity and QOL and mental health has not been examined in depth.…”