Health economics of osteoporosis

Borgström, Fredrik; Kanis, John А.

doi:10.1016/j.beem.2008.07.005

Cited by 29 publications

(18 citation statements)

References 128 publications

(186 reference statements)

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“…Osteoporotic fractures are a major health issue worldwide [1,2]. Traditional public health policies have aimed at reducing risk factors associated with bone mass losses during adulthood to prevent osteoporotic fractures in later life [3].…”

Section: Introductionmentioning

confidence: 99%

The influence of birth weight and length on bone mineral density and content in adolescence: The Tromsø Study, Fit Futures

et al. 2017

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The influence of birth weight and length on bone mineral density and content in adolescence. The Tromsø Study, Fit Futures.Purpose: The influence of birth weight and length on bone mineral density and content later in life is unclear, especially in adolescence. This study evaluated the impact of birth weight and length on bone mineral density and content among adolescents.Methods: We included 961 participants from the population-based Fit Future study (2010)(2011). Dual-energy X-ray absorptiometry (DXA) was used to measure bone mineral density (BMD) and bone mineral content (BMC) at femoral neck (FN), total hip (TH) and total body (TB). BMD and BMC measures were linked with birth weight and length ascertained from the Medical Birth Registry of Norway. Linear regression models were used to investigate the influence of birth parameters on BMD and BMC. Corresponding analyses using birth length as exposure gave significantly positive associations with BMC at all sites in both sexes. The significant positive association between birth weight 3 and BMC-TB in girls, and birth length and BMC-TB in boys remained after multivariable adjustment.Conclusions: We found a positive association between birth size and BMC in adolescence.However, this association was attenuated after adjustment for weight, height and physical activity during adolescence.

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Section: Introductionmentioning

confidence: 99%

The influence of birth weight and length on bone mineral density and content in adolescence: The Tromsø Study, Fit Futures

et al. 2017

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“…An important component of health economic assessment is the comparison of two or more treatment alternatives in patients at the same level of risk with the ultimate target of balancing benefit against cost [3]. A related objective may be identification of subgroups of patients in whom a treatment is particularly cost-effective.…”

Section: Health Economics In Osteoporosismentioning

confidence: 99%

“…Treating populations at greater risk for fracture would be expected to reduce the burden of disease and health care costs. In this context, the fracture risk assessment tool FRAX [3,8] is set to improve the identification of high-risk patients and is likely to have an increasing impact in health economics.…”

Section: Health Economics In Osteoporosismentioning

confidence: 99%

“…Health economics is becoming more important in osteoporosis due not only to the increasing requirement for the evaluation of costeffectiveness of treatments by decision-and policymakers, but also to inform guidelines for the management of disease. An aim of cost-effectiveness analysis in the context of osteoporosis is to estimate the number of fracture events avoided by treatment and translate this into savings in terms of cost, morbidity, and mortality (commonly expressed as quality-adjusted life years, QALYs, gained) [3].…”

Section: Introductionmentioning

confidence: 99%

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Partial adherence: a new perspective on health economic assessment in osteoporosis

et al. 2011

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“…The guideline does not, however, come into effect until there has been a minimal trauma fracture (Royal Australian College of General Practitioners, 2010). Risk assessment tools have also been developed which combine clinical risk factors and DXA measurements (Borgström & Kanis, 2008;Unnanuntana et al, 2010). Thus DXA scans are only provided to those considered at risk of osteoporosis or in response to a minimal trauma fracture.…”

Section: Introductionmentioning

confidence: 99%