Health challenges in Kazakhstan and Central Asia

Adambekov, Shalkar; Kaiyrlykyzy, Aiym; Igissinov, Nurbek; Linkov, Faina

doi:10.1136/jech-2015-206251

Cited by 33 publications

(28 citation statements)

References 24 publications

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“…Despite the strong association of dyslipidemia with cardiovascular risk, with a few exceptions [ 18 ] there is a striking lack of studies of this important aspect of cardiovascular health in the Central Asian region. The available information is largely limited to WHO reports on cardiovascular disease risk factors, with the source of the data for this region sometimes uncertain and or being based on extrapolations from other regions [ 19 , 20 ].…”

Section: Discussionmentioning

confidence: 99%

Prevalence, awareness, treatment and control of dyslipidemia in older persons in urban and rural population in the Astana region, Kazakhstan

et al. 2017

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BackgroundDespite high cardiovascular mortality in Central Asian republics of the former Soviet Union, there is limited information about major risk factors, including blood lipids. We investigated the prevalence of impaired concentrations of blood lipids, the awareness, treatment and control of hypercholesterolemia, and factors associated with these indicators in urban and rural populations in Kazakhstan.MethodsWe conducted a cross-sectional study of random urban and rural population samples (the state capital Astana and Akmol village). Men and women aged 50–74 years were examined; a total of 954 adults participated (response rate 59%). Serum concentrations of total, LDL and HDL cholesterol and triglycerides and a range of other cardiovascular risk factors were measured.ResultsThe overall prevalence of hypercholesterolemia (total cholesterol ≥6.2 mmol/l) was 37%; among subjects with hypercholesterolemia, 57% were aware of their condition, 41% took medication and 23% had total cholesterol <6.2 mmol/l (4.5% <5 mmol/l). The prevalence, awareness, treatment, and control of hypercholesterolemia were all higher in the urban than the rural area. Similarly, the proportions of subjects with impaired concentrations of specific lipids fractions were also considerably higher in the urban population. Most associations with other covariates were in the expected direction.ConclusionsThis study found relatively high prevalence of dyslipidemia in the Kazakh population, and the blood lipid profile was less favourable in the urban area. These pronounced urban–rural differences may be related to urbanization, the associated nutrition transition and to access to health care.Electronic supplementary materialThe online version of this article (doi:10.1186/s12889-017-4629-5) contains supplementary material, which is available to authorized users.

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Section: Discussionmentioning

confidence: 99%

Prevalence, awareness, treatment and control of dyslipidemia in older persons in urban and rural population in the Astana region, Kazakhstan

et al. 2017

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“…Another difficulty in assessing the burden of the diseases, is the low scientific output from Kyrgyzstan which is often published in Russian [ 11 , 12 ].…”

Section: Introductionmentioning

confidence: 99%

The Burden of Zoonoses in Kyrgyzstan: A Systematic Review

Counotte

Minbaeva²,

Usubalieva³

et al. 2016

PLoS Negl Trop Dis

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IntroductionZoonotic disease (ZD) pose a serious threat to human health in low-income countries. In these countries the human burden of disease is often underestimated due to insufficient monitoring because of insufficient funding. Quantification of the impact of zoonoses helps in prioritizing healthcare needs. Kyrgyzstan is a poor, mountainous country with 48% of the population employed in agriculture and one third of the population living below the poverty line.Methodology/Principal FindingsWe have assessed the burden of zoonoses in Kyrgyzstan by conducting a systematic review. We have used the collected data to estimate the burden of ZDs and addressed the underestimation in officially reported disease incidence. The estimated incidences of the ZDs were used to calculate incidence-based Disability Adjusted Life Years (DALYs). This standardized health gap measure enhances comparability between injuries and diseases. The combined burden for alveolar echinococcosis, cystic echinococcosis, brucellosis, campylobacteriosis, congenital toxoplasmosis, non-typhoidal salmonellosis and rabies in Kyrgyzstan in 2013 was 35,209 DALYs [95% Uncertainty interval (UI):13,413–83,777]; 576 deaths [95% UI: 279–1,168] were attributed to these infections. We estimate a combined median incidence of ZDs of 141,583 cases [95% UI: 33,912–250,924] in 2013. The highest burden was caused by non-typhoidal Salmonella and Echinococcus multilocularis, respectively 14,792 DALYs [95% UI: 3,966–41,532] and 11,915 DALYs [95% UI: 4,705–27,114] per year.Conclusion/SignificanceThe health impact of zoonoses in Kyrgyzstan is substantial, comparable to that of HIV. Community-based surveillance studies and hospital-based registration of all occurrences of zoonoses would increase the accuracy of the estimates.

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“…The former, due to deficiency in the hemostatic system cause the development of hemorrhagic complications, while the latter represent dishormonal manifestations. However, issues of reproductive health of women with chronic viral hepatitis are understudied [8]. Consequently, studying reproductive health and features of immune response in women with chronic viral hepatitis is of interest.…”

Section: Introductionmentioning

confidence: 99%

Reproductive dysfunctions in viral hepatitis

Kurmanova

Локшин

2016

Gynecological Endocrinology

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The viral hepatitis abnormalities in the female reproductive system are due to hepatic and extrahepatic damage. On the background of HBV- and HCV-infections, menstrual disorders prevail in the structure of reproductive system pathology; disorders of reproductive function in the form of pregnancy loss and infertility are detected in each second case. Depression of T-cell immunity in the immune status is observed in the patients with intact reproductive function. When miscarriage was in past medical history then divergent changes subpopulations of lymphocytes are found. When patients have infertility, signify depression of T-cell immunity is observed with a decrease in total T-cells, T-helper cells and active lymphocytes.

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Health challenges in Kazakhstan and Central Asia

Cited by 33 publications

References 24 publications

Prevalence, awareness, treatment and control of dyslipidemia in older persons in urban and rural population in the Astana region, Kazakhstan

Prevalence, awareness, treatment and control of dyslipidemia in older persons in urban and rural population in the Astana region, Kazakhstan

The Burden of Zoonoses in Kyrgyzstan: A Systematic Review

Reproductive dysfunctions in viral hepatitis

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