Head Fixation Device for Reproducible Position Alignment in Transmission CT and Positron Emission Tomography

Bergström, Mats; Boëthius, J.; Eriksson, L. S.; Greitz, T.; Ribbe, T.; Widén, L.

doi:10.1097/00004728-198102000-00027

Cited by 287 publications

(112 citation statements)

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“…(1980, 198 1) in schizophrenic patients prior to medication trials demonstrated reduced frontal cortical metabolism (60% of normal values), which increased (75% of normal) following drug therapy. Decreased frontal-to-temporal cortical ratios (0.9 in patients, n = 9, versus 1.23 in controls, n = 2; p < 0.05) were also reported by Widen et al (1981) using llC labeled glucose as an index of glucose utilization. Buchsbaum et al .…”

Section: Miscellaneous Disordersmentioning

confidence: 65%

Study of Cerebral Function with Positron Computed Tomography

Phelps¹,

Mazziotta

Huang³

1982

J Cereb Blood Flow Metab

365

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Section: Miscellaneous Disordersmentioning

confidence: 65%

Study of Cerebral Function with Positron Computed Tomography

Phelps¹,

Mazziotta

Huang³

1982

J Cereb Blood Flow Metab

365

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“…The time from the tracer injection to the arrival of the bolus to the head was approximately 15 s and was followed by a 1-min tracer up-take scan. Individual plaster head support was made for each subject to minimise head movements during the PET imaging (Bergstro Èm et al, 1981). rCBF was measured in four different conditions:…”

Section: Experimental Designmentioning

confidence: 99%

Pain-related cerebral activation is altered by a distracting cognitive task

Petrović

Petersson

Ghatan

et al. 2000

Pain

380

224

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It has previously been suggested that the activity in sensory regions of the brain can be modulated by attentional mechanisms during parallel cognitive processing. To investigate whether such attention-related modulations are present in the processing of pain, the regional cerebral blood¯ow was measured using [15 O]butanol and positron emission tomography in conditions involving both pain and parallel cognitive demands. The painful stimulus consisted of the standard cold pressor test and the cognitive task was a computerised perceptual maze test. The activations during the maze test reproduced ®ndings in previous studies of the same cognitive task. The cold pressor test evoked signi®cant activity in the contralateral S1, and bilaterally in the somatosensory association areas (including S2), the ACC and the mid-insula. The activity in the somatosensory association areas and periaqueductal gray/midbrain were signi®cantly modi®ed, i.e. relatively decreased, when the subjects also were performing the maze task. The altered activity was accompanied with signi®cantly lower ratings of pain during the cognitive task. In contrast, lateral orbitofrontal regions showed a relative increase of activity during pain combined with the maze task as compared to only pain, which suggests the possibility of the involvement of frontal cortex in modulation of regions processing pain.

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“…To ensure that the radioactivity levels in the subjects had returned to background before starting a new scan, at least 10 min elapsed between successive scans. Individual plaster head support was made for each patient to minimize head movements during the PET imaging (Bergstro Èm et al, 1981).…”

Section: Pet Scanningmentioning

confidence: 99%

A PET activation study of dynamic mechanical allodynia in patients with mononeuropathy

Petrović¹,

Ingvar²,

Stone‐Elander³

et al. 1999

Pain

152

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The objective of this study was to investigate the central processing of dynamic mechanical allodynia in patients with mononeuropathy. Regional cerebral blood¯ow, as an indicator of neuronal activity, was measured with positron emission tomography. Paired comparisons were made between three different states; rest, allodynia during brushing the painful skin area, and brushing of the homologous contralateral area. Bilateral activations were observed in the primary somatosensory cortex (S1) and the secondary somatosensory cortex (S2) during allodynia compared to rest. The S1 activation contralateral to the site of the stimulus was more expressed during allodynia than during innocuous touch. Signi®cant activations of the contralateral posterior parietal cortex, the periaqueductal gray (PAG), the thalamus bilaterally and motor areas were also observed in the allodynic state compared to both non-allodynic states. In the anterior cingulate cortex (ACC) there was only a suggested activation when the allodynic state was compared with the non-allodynic states. In order to account for the individual variability in the intensity of allodynia and ongoing spontaneous pain, rCBF was regressed on the individually reported pain intensity, and signi®cant covariations were observed in the ACC and the right anterior insula. Signi®cantly decreased regional blood¯ow was observed bilaterally in the medial and lateral temporal lobe as well as in the occipital and posterior cingulate cortices when the allodynic state was compared to the non-painful conditions. This ®nding is consistent with previous studies suggesting attentional modulation and a central coping strategy for known and expected painful stimuli. Involvement of the medial pain system has previously been reported in patients with mononeuropathy during ongoing spontaneous pain. This study reveals a bilateral activation of the lateral pain system as well as involvement of the medial pain system during dynamic mechanical allodynia in patients with mononeuropathy. q 1999 International Association for the Study of Pain. Published by Elsevier Science B.V.

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Head Fixation Device for Reproducible Position Alignment in Transmission CT and Positron Emission Tomography

Cited by 287 publications

References 0 publications

Study of Cerebral Function with Positron Computed Tomography

Study of Cerebral Function with Positron Computed Tomography

Pain-related cerebral activation is altered by a distracting cognitive task

A PET activation study of dynamic mechanical allodynia in patients with mononeuropathy

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