Head and Neck Hemangiopericytoma

Malign Recurrence of Primary Chest Wall Hemangiopericytoma in the Lung after Four Years: A Case Report and Review of the Literature

“…Therefore, the function of pericytes is unknown. However, it is believed that they provide the contractile strength of the capillaries and, thereby, the mechanical support [5]. HPC, which is particularly seen in adults and rarely seen in children, shows an equal distribution in both genders.…”

“…The tumor is well limited and without capsule and tends to show a slow grow-up. If the tumor has a focal necrotic area and shows increased cellularity, it is considered as malign [5]. Malign HPC constitutes <1% of all vascular tumors and 5% of all sarcomatous tumors [12].…”

“…The tumors that show more than four mitoses, a focal area of necrosis, and increased cellularity on a magnification ×10 are considered as malign [4]. Generally, HPC is treated with preoperative embolisation followed by a full surgical resection [5]. In the postoperative malign HPC cases, radiotherapy with or without chemotherapy may be given as a palliative or rescue therapy [5].…”

“…Generally, HPC is treated with preoperative embolisation followed by a full surgical resection [5]. In the postoperative malign HPC cases, radiotherapy with or without chemotherapy may be given as a palliative or rescue therapy [5]. In our paper, we presented our case, who was treated for primary chest wall hemangiopericytoma, who showed a lung metastasis at the end of 4 years, and who developed a pathological fracture of the right humerus at the end of approximately 2 years, because hemangiopericytoma is rarely seen in chest wall as a primary tumor and efficient chemotherapeutic agents given concomitantly to surgical therapy or radiotherapy offer long life expectancy.…”

Extensive tongue hemangiopericytoma in a child: modified combined modality of treatment to preserve well functioning tongue

“…The histologic appearance does not reliably predict the biologic behavior of the tumor, which is therefore considered as borderline tumor requiring close clinical follow-up. Significant cytologic atypia, frequent mitosis (more than 4/10 HPF), and tumor necrosis are the features associated with malignant behavior, with a metastatic rate of 78% [6,24].…”