Head and Neck Cancer—A Clinicopathological Study in a Tertiary Care Center

Adeyemi, B F; Adekunle, Lola; Kolude, Bamidele; Akang, E. E. U.; Lawoyin, J O

doi:10.1016/s0027-9684(15)31343-2

Cited by 51 publications

(108 citation statements)

References 25 publications

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“…This is not in agreement with other studies conducted in the south-west 15] and north-central [16] regions of Nigeria, in which lymphomas were more frequent than sarcomas. Our findings, however, corroborate the study of lymphomas in Nigeria by Berry [17] in 1964 which reported a decrease in the incidence of lymphomas from the south (an area with high annual rainfall and holoendemicity of malaria) to the north (an area with low annual rainfall) of Nigeria.…”

Section: Discussioncontrasting

confidence: 99%

Evaluation of the histopathology of orofacial lesions in a North-East Nigerian tertiary centre

et al. 2013

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The range of diagnosed lesions from our study was diverse, though our results do not represent the actual prevalence of orofacial lesions within the general population, but simply reflect the frequency of histologically diagnosed lesions at a health center in North-East Nigeria. This survey has shown that most oro-facial lesions studied were benign neoplasms and that most of these neoplasms were from the mandible.

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Section: Discussioncontrasting

confidence: 99%

Evaluation of the histopathology of orofacial lesions in a North-East Nigerian tertiary centre

et al. 2013

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“…Some of these reports focused mainly on malignant tumors but it is established that the commonest malignancy of the head and neck region is Carcinoma. [14][15][16][17] This is the pattern observed all over the world. 1,18,19 Some local studies by Bhatia 20 and Amusa et al 21 had ranked lymphoma higher than carcinoma but these are exceptions.…”

Section: Discussionmentioning

confidence: 94%

“…30 This is similar to what obtains in studies in some parts of the country and other countries. 17,23,31 The variations seen in the regional demographics of head and neck tumors in the country could be accounted for by the differences in data collection methods and certain aetiological factors that may be unique to those regions. A proper tumor registry in each region, harmonized with a national cancer registry may resolve some of these discrepancies.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of head and neck tumours in Calabar, South Eastern Nigeria

2016

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Head and neck tumours constitute a wide spectrum of heterogeneous tumours affecting different anatomical sites in the head and neck region, with varying histology and biological behaviors.The different sites include sinonasal, nasopharyngeal, parapharyngeal, oral and oropharyngeal, hypopharyngeal, laryngeal, otologic, orbital, thyroid and parathyroid, and salivary gland tumours. The different subtypes include squamous cell carcinomas, paranasal sinus and nasopharyngeal carcinomas, salivary gland cancers, melanomas, sarcomas, lymphomas and lymphatic tumours, orbital tumours, thyroid and parathyroid gland tumours and other neuroendocrine tumours. [1][2][3] Malignancies in the head and neck region though relatively rare, compared to other regions of the body, they contribute significantly to morbidity and mortality in affected patients. Background: Malignancies in the head and neck region though relatively rare, compared to other regions of the body, they contribute significantly to morbidity and mortality in affected patients. In Nigeria, the burden of managing head and Neck malignancies is enormous and there is yet to be a unified record of nation-wide incidence of malignancies involving the head and neck region despite the fact the head and neck malignancies have been diagnosed and documented since the 1960's. The histological pattern and frequency however seems to have some slight variation depending on the region and the identified aetiological risk factors. Aims and Objectives:The aim of this study was to determine the pattern of head and neck tumours seen in the region and the commonest malignancies in the cohort. By comparing the relative prevalence of the lesions with other centers in the country and international published literature we hope to make a case for proper tumour registry and move for nation-wide studies. Materials and Methods:The authors reviewed the histopathological data of the tumor registry at the University of Calabar Teaching Hospital, a major referral Center in South-Eastern Nigeria between 2005 and 2012. All cases of head and Neck tumours with histological diagnosis were included for analysis, their demographic data were obtained and analyzed using SPSSv16. Results: Two hundred and twenty-five specimens from the head and neck region were analyzed during this 6 year period giving an average of 34 cases per year. The Male:Female ratio was 1.2:1. The age range was from 2 years to 76 years with overall mean of 32.7 years. One hundred and forty-five cases (63.3%) were benign while 84 malignant cases (36.7%) were recorded for the study period. The average number of new malignant cases seen was 14 per year. Malignancies were commoner in those less than 50 years of age and were mostly those of epithelial origin. Conclusion: Variations in the regional demographics of head and neck tumors in the country could be accounted for by the differences in data collection methods and certain aetiological factors that may be unique to those regions. A proper tumor registry in each region, harmonized with ...

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“…The two most common head and neck cancers in their series were SCC, which accounted for 47.8% of cases, followed by lymphomas which accounted for 19.3% [53]. Adisa et al [27] reported that the epithelial malignancies (carcinomas) constitute 73.4% of all the cases while Lymphomas and sarcomas were 17.5% and 8.9% of cases respectively.…”

Section: Histopathological Types Of the Oral Cancersmentioning

confidence: 91%

“…Also, Adeyemi et al [53] reported a prevalence of 71.1% for carcinomas among head and neck cancers analyzed in Ibadan (SouthWest, Nigeria). The two most common head and neck cancers in their series were SCC, which accounted for 47.8% of cases, followed by lymphomas which accounted for 19.3% [53].…”

Section: Histopathological Types Of the Oral Cancersmentioning

confidence: 99%

Oral Cancer- The Nigerian Perspective

Okoh¹,

Okoh²

2017

J Mol Biomark Diagn

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Study background: In our environment, oral cancer is one of the most common lethal diseases encountered in dental practice. It is frequently diagnosed in the late stages because most patients present late in the course of the disease. This may be attributed to their low socioeconomic status, illiteracy, and some traditional beliefs in alternative native therapies. Some authors have reported on oral cancers specifically in their individual geographic settings; however, there is a paucity of reviews on Oral cancers generally in our environment. This study aims to review the prevalence, awareness and clinicopathologic patterns of oral cancers across the different geographic zones in Nigeria.Methods: Information was sourced from journals, electronic data base such as Medline, Pubmed, Elsevier ScienceDirect and personal research work.Result: Several prevalence rates have been reported in different geopolitical locations in our environment. Orofacial carcinomas were reported mostly in the older age groups while the Orofacial sarcomas were found in the slightly younger age groups. Squamous cell carcinoma was the predominant histopathological type. There is a low level of awareness of these lesions among the low socio-economic groups which makes them present late in our health care facilities hence a poor prognosis. Conclusion:There is a need for increased awareness, advocacy and preventive care and early detection.

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Head and Neck Cancer—A Clinicopathological Study in a Tertiary Care Center

Cited by 51 publications

References 25 publications

Evaluation of the histopathology of orofacial lesions in a North-East Nigerian tertiary centre

Evaluation of the histopathology of orofacial lesions in a North-East Nigerian tertiary centre

Prevalence of head and neck tumours in Calabar, South Eastern Nigeria

Oral Cancer- The Nigerian Perspective

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