Harmful Cyanobacterial Blooms (HCBs): innovative green bioremediation process based on anti-cyanobacteria bioactive natural products

Zerrifi, Soukaina El Amrani; Mugani, Richard; Redouane, El Mahdi; Khalloufi, Fatima El; Campos, Alexandre; Vasconcelos, Vı́tor; Oudra, Brahim

doi:10.1007/s00203-020-02015-6

Cited by 15 publications

(8 citation statements)

References 168 publications

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“…Cyanobacteria are known to secrete a large number of various toxins with hepatotoxic effects as well as known neurotoxins such as kalkitoxin and saxitoxin, and more than 100 species of cyanobacteria have been shown to secrete toxins (Singh et al ., 2005 ; Sacilotto Detoni et al ., 2016 ; Zerrifi et al ., 2021 ). Extracts from the marine cyanobacterium Trichodesmium erythraeum from microalgal blooms on the Brazilian coastline were found to contain microcystins, cylindrospermopsins and saxitoxins, and showed toxic antimitotic activity against larvae of the green sea urchin ( Lytechinus variegatus ) but not against mice (Proença et al ., 2009 ).…”

Section: Discussion and Limitationsmentioning

confidence: 99%

Health benefits of microalgae and their microbiomes

Krohn

Menanteau–Ledouble

Hageskal

et al. 2022

Microbial Biotechnology

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Microalgae comprise a phylogenetically very diverse group of photosynthetic unicellular pro-and eukaryotic organisms growing in marine and other aquatic environments. While they are well explored for the generation of biofuels, their potential as a source of antimicrobial and prebiotic substances have recently received increasing interest. Within this framework, microalgae may offer solutions to the societal challenge we face, concerning the lack of antibiotics treating the growing level of antimicrobial resistant bacteria and fungi in clinical settings. While the vast majority of microalgae and their associated microbiota remain unstudied, they may be a fascinating and rewarding source for novel and more sustainable antimicrobials and alternative molecules and compounds. In this review, we present an overview of the current knowledge on health benefits of microalgae and their associated microbiota. Finally, we describe remaining issues and limitation, and suggest several promising research potentials that should be given attention.

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Section: Discussion and Limitationsmentioning

confidence: 99%

Health benefits of microalgae and their microbiomes

Krohn

Menanteau–Ledouble

Hageskal

et al. 2022

Microbial Biotechnology

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“…Bioactive compounds have found a range of applications in bioremediation sectors as well, in the form of coagulants (Ibrahim et al 2021), biofilms (Mugge et al 2021), bioactive extracts (Zerrifi et al 2018), and so on. A wide range of bioactive compounds obtained from various sources has shown promising activity against harmful algal blooms (HAB), including α-linolenic, oleic, and palmitic acids from Botryococcus braunii, diethyl phthalate from Stoechospermum marginatum, and so on (Zerrifi et al 2018(Zerrifi et al , 2021. Similarly, bioaccumulation of nutrients, as well as metals (Cd, Cu, Zn, Pb, Cr) by Sargassum, has triple benefits in terms of reducing eutrophication and coastal metal pollution in addition to sequestering metals and useful bioactive compounds which could then be used in pharmaceutical, cosmetic, food, and fertilizer industries (Saldarriaga-Hernandez et al 2020).…”

Section: Bioremediation Sectormentioning

confidence: 99%

A critical look at challenges and future scopes of bioactive compounds and their incorporations in the food, energy, and pharmaceutical sector

Pai

Hebbar

Selvaraj

2022

Environ Sci Pollut Res

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Bioactive compounds refer to secondary metabolites extracted from plants, fungi, microbes, or animals. Besides having pharmacological or toxicological effects on organisms leading to utilization in food and pharmaceutical industries, the discovery of novel properties of such compounds has led to the diversification of their applications, ranging from cosmetics and functionalized biomaterials to bioremediation and alternate fuels. Conventional time-consuming and solvent-intensive methods of extraction are increasingly being replaced by green solvents such as ionic liquids, supercritical fluids, and deep eutectic solvents, as well as non-conventional methods of extraction assisted by microwaves, pulse electric fields, enzymes, ultrasound, or pressure. These methods, along with advances in characterization and optimization strategies, have boosted the commercial viability of extraction especially from agrowastes and organic residues, promoting a sustainable circular economy. Further development of microfluidics, optimization models, nanoencapsulation, and metabolic engineering are expected to overcome certain limitations that restrict the growth of this field, in the context of improving screening, extraction, and economy of processes, as well as retaining biodiversity and enhancing the stability and functionality of such compounds. This review is a compilation of the various extraction and characterization methods employed for bioactive compounds and covers major applications in food, pharmacy, chemicals, energy, and bioremediation. Major limitations and scope of improvement are also discussed. Graphical abstract

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“…Biological control measures, such as plant-derived allelochemicals [ 10 ] or other biologically derived molecules [ 11 ], have been tested. Algal predation by bacteria [ 12 ] and algicidal bacteria [ 13 ] have also been evaluated.…”

Section: Introductionmentioning

confidence: 99%

Prophylactic Addition of Glucose Suppresses Cyanobacterial Abundance in Lake Water

Vesper

Sienkiewicz

Struewing

et al. 2022

Life

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To mitigate harmful cyanobacterial blooms (HCBs), toxic algicides have been used, but alternative methods of HCB prevention are needed. Our goal was to test the prophylactic addition of glucose to inhibit HCB development, using Microcystis and the toxin microcystin as the HCB model. Water samples were collected weekly, from 4 June to 2 July, from Harsha Lake in southwestern Ohio during the 2021 algal bloom season. From each weekly sample, a 25 mL aliquot was frozen for a 16S rRNA gene sequencing analysis. Then, 200 mL of Harsha Lake water was added to each of the three culture flasks, and glucose was added to create concentrations of 0 mM (control), 1.39 mM, or 13.9 mM glucose, respectively. The microcystin concentration in each flask was measured after 1 and 2 weeks of incubation. The results showed an 80 to 90% reduction in microcystin concentrations in glucose-treated water compared to the control. At the end of the second week of incubation, a 25 mL sample was also obtained from each of the culture flasks for molecular analysis, including a 16S rRNA gene sequencing and qPCR-based quantification of Microcystis target genes. Based on these analyses, the glucose-treated water contained significantly lower Microcystis and microcystin producing gene (mcy) copy numbers than the control. The 16S rRNA sequencing analysis also revealed that Cyanobacteria and Proteobacteria were initially the most abundant bacterial phyla in the Harsha Lake water, but as the summer progressed, Cyanobacteria became the dominant phyla. However, in the glucose-treated water, the Cyanobacteria decreased and the Proteobacteria increased in weekly abundance compared to the control. This glucose-induced proteobacterial increase in abundance was driven primarily by increases in two distinct families of Proteobacteria: Devosiaceae and Rhizobiaceae. In conclusion, the prophylactic addition of glucose to Harsha Lake water samples reduced Cyanobacteria’s relative abundance, Microcystis numbers and microcystin concentrations and increased the relative abundance of Proteobacteria compared to the control.

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Harmful Cyanobacterial Blooms (HCBs): innovative green bioremediation process based on anti-cyanobacteria bioactive natural products

Cited by 15 publications

References 168 publications

Health benefits of microalgae and their microbiomes

Health benefits of microalgae and their microbiomes

A critical look at challenges and future scopes of bioactive compounds and their incorporations in the food, energy, and pharmaceutical sector

Prophylactic Addition of Glucose Suppresses Cyanobacterial Abundance in Lake Water

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