Hantaviruses and Hantavirus Pulmonary Syndrome, Maranhão, Brazil

Rosa, Elizabeth Salbé Travassos da; Lemos, Elba Regina Sampaio de; Medeiros, Daniele Barbosa de Almeida; Simith, Darlene B.; Pereira, Armando de Souza; Elkhoury, Mauro R.; Mendes, Wellington S.; Vidigal, José R.B.; Oliveira, Renata Carvalho de; D’Andrea, Paulo Sérgio; Bonvicino, Cibele Rodrigues; Cruz, Ana Cecília Ribeiro; Nunes, Márcio Roberto Teixeira; Vasconcelos, Pedro Fernando da Costa

doi:10.3201/eid1612.100418

Cited by 20 publications

(8 citation statements)

References 15 publications

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“…We obtained N gene partial nucleotide sequences by using the Sanger method with the same primers ( 3 , 4 , 6 , 9 ). At least 3 amplicons per sample were sequenced in both directions to improve coverage and confidence for results.…”

Section: The Studymentioning

confidence: 99%

Molecular Epidemiology of Laguna Negra Virus, Mato Grosso State, Brazil

Rosa¹,

Medeiros²,

Nunes³

et al. 2012

Emerg. Infect. Dis.

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Section: The Studymentioning

confidence: 99%

Molecular Epidemiology of Laguna Negra Virus, Mato Grosso State, Brazil

Rosa¹,

Medeiros²,

Nunes³

et al. 2012

Emerg. Infect. Dis.

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“…In Brazil, specimens from Anajatuba and Santa Rita in Maranhão (locality marked with a triangle in Fig. ) were infected with the Anajatuba hantavirus (Travassos da Rosa et al ., , ). These individuals were identified as O. fornesi without any alpha taxonomic study leading to that species denomination: no cyt b sequences of these specimens are available in GenBank.…”

Section: Discussionmentioning

confidence: 99%

“…Therefore, after considering all the available information, we hypothesize that the specimens analysed by Travassos da Rosa et al . (, ) do not correspond to O. fornesi , and thus this species would not be the natural reservoir of the Anajatuba genotype.…”

Section: Discussionmentioning

confidence: 99%

The molecular phylogenetics of the genusOligoryzomys(Rodentia: Cricetidae) clarifies rodent host-hantavirus associations

et al. 2014

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Several species of the genus Oligoryzomys are natural hosts of different hantavirus genotypes affecting humans. The systematics of the genus is confusing, which complicates the identification of the rodent host and hence the potential endemic areas of hantavirus pulmonary syndrome. In this study, we analyse molecular data to infer phylogenetic relationships among Central and South American specimens of Oligoryzomys, and compare our results with previously published data on karyotypic, geographic distribution and host–virus associations to solve contradictory taxonomic reports. We identified 25 clades, each one corresponding to a different putative species. The phylogenetic trees show that Oligoryzomys longicaudatus is strongly related to the Oligoryzomys flavescens complex, which comprises four clades; Oligoryzomys nigripes is related to Oligoryzomys stramineus, Oligoryzomys vegetus is related to Oligoryzomys fulvescens from Central America, and Oligoryzomys brendae is the sister species of Oligoryzomys aff. destructor. We identified the following rodent host–hantavirus genotype relationships: O. longicaudatus–Andes; O. flavescens ‘West'–Bermejo; O. flavescens ‘East'–Lechiguanas; O. nigripes–Juquitiba; Oligoryzomys microtis–Rio Mamore and Rio Mamore‐3; Oligoryzomys chacoensis–Oran; Oligoryzomys costaricencis–Choclo; Oligoryzomys delicatus–Maporal; Oligoryzomys utiaritensis–Castelo dos Sonhos; Oligoryzomys sp. RT2012–Rio Mamore‐4; Oligoryzomys sp. (and not Oligoryzomys fornesi)–Anajatuba. This work, besides contributing to the development of prevention programmes for hantavirus epidemiology in Latin America, represents a comprehensive update of the systematics of the genus Oligoryzomys. © 2014 The Linnean Society of London

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“…The main reservoirs include the following: rodents of the genus Peromyscus in the USA and Canada, associated with the hantaviruses Sin Nombre, New York, Monongahela and Montano. The Montano virus is found in Mexico [ 165 , 166 , 167 ] rodents of the genus Oligoryzomys , associated with the hantaviruses Andes (ANDV), Oran, Lechiguanas and Bermejo in Argentina; ANDV in Chile; Choclo in Panama; Central Plata in Uruguay; and the genotypes Juquitiba, Castelo dos Sonhos, Anajatuba and Rio Mamore in Brazil [ 18 , 168 , 169 , 170 , 171 , 172 ] rodents of the genus Calomys , which are reservoirs for Laguna Negra in Paraguay, Bolivia and Brazil [ 173 , 174 ]; rodents of the genus Necromys , which are reservoirs for the hantaviruses Maciel in Argentina and Araraquara in Brazil [ 169 , 170 ]; rodents of the genus Akodon , which are reservoirs of the viruses Pergamino in Argentina and Jabora in Brazil and Paraguay [ 169 , 175 , 176 , 177 ] rodents of the genus Holochilus , which are reservoirs of the viruses Rio Mearim in Brazil and Alto Paraguay in Paraguay (See Supplementary Table 2 ). …”

Section: Hantavirus Hostsmentioning

confidence: 99%

“…rodents of the genus Oligoryzomys , associated with the hantaviruses Andes (ANDV), Oran, Lechiguanas and Bermejo in Argentina; ANDV in Chile; Choclo in Panama; Central Plata in Uruguay; and the genotypes Juquitiba, Castelo dos Sonhos, Anajatuba and Rio Mamore in Brazil [ 18 , 168 , 169 , 170 , 171 , 172 ]…”

Section: Hantavirus Hostsmentioning

confidence: 99%

Hantavirus Reservoirs: Current Status with an Emphasis on Data from Brazil

Oliveira

Guterres

Fernandes

et al. 2014

Viruses

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Since the recognition of hantavirus as the agent responsible for haemorrhagic fever in Eurasia in the 1970s and, 20 years later, the descovery of hantavirus pulmonary syndrome in the Americas, the genus Hantavirus has been continually described throughout the World in a variety of wild animals. The diversity of wild animals infected with hantaviruses has only recently come into focus as a result of expanded wildlife studies. The known reservoirs are more than 80, belonging to 51 species of rodents, 7 bats (order Chiroptera) and 20 shrews and moles (order Soricomorpha). More than 80genetically related viruses have been classified within Hantavirus genus; 25 recognized as human pathogens responsible for a large spectrum of diseases in the Old and New World. In Brazil, where the diversity of mammals and especially rodents is considered one of the largest in the world, 9 hantavirus genotypes have been identified in 12 rodent species belonging to the genus Akodon, Calomys, Holochilus, Oligoryzomys, Oxymycterus, Necromys and Rattus. Considering the increasing number of animals that have been implicated as reservoirs of different hantaviruses, the understanding of this diversity is important for evaluating the risk of distinct hantavirus species as human pathogens.

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Hantaviruses and Hantavirus Pulmonary Syndrome, Maranhão, Brazil

Cited by 20 publications

References 15 publications

Molecular Epidemiology of Laguna Negra Virus, Mato Grosso State, Brazil

Molecular Epidemiology of Laguna Negra Virus, Mato Grosso State, Brazil

The molecular phylogenetics of the genusOligoryzomys(Rodentia: Cricetidae) clarifies rodent host-hantavirus associations

Hantavirus Reservoirs: Current Status with an Emphasis on Data from Brazil

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