Handbook of Neurosurgery

Greenberg, Mark S.

doi:10.1055/b-006-149702

Cited by 232 publications

(295 citation statements)

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“…Almost half (48%) of all patients underwent anterior reconstruction with allograft bone and cage con- (7)(8)(9)(10)(11)(12) or instability (13)(14)(15)(16)(17)(18) were undefined, and the survival difference between the 2 groups was not statistically significant by log-rank test (p = 0.12). structs, and 39% of patients had no anterior reconstruction (Table 4).…”

Section: Instrumentation and Surgical Reconstructionmentioning

confidence: 96%

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Outcomes following surgical intervention for impending and gross instability caused by multiple myeloma in the spinal column

Zadnik

Goodwin

Karami

et al. 2015

SPI

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OBJECT Multiple myeloma is the most common primary tumor of the spine and is the most common primary malignant tumor of bone. Although spinal myeloma is classically a radiosensitive lesion, clinical or radiographic signs of instability merit surgical intervention. The authors present the epidemiology, surgical indications, and outcome data of a series of consecutive cases involving 31 surgically treated patients with diagnoses of multiple myeloma and plasmacytoma of the spine (the largest such series reported to date). METHODS Surgical instability was the criterion for operative intervention in this patient cohort. The Spinal Instability Neoplastic Score (SINS) was used to make this assessment of instability. The cases were analyzed using location of the lesion, spinal levels involved, Frankel score, adjuvant therapy, functional outcome, and patient survival. RESULTS All patients undergoing surgical intervention were determined to have indeterminate or gross spinal column instability according to SINS criteria. The median survival was 78.9 months. No significant difference in survival was seen for patients with higher SINS scores or for older patients (> 55 years). There was a statistically significant difference in survival benefit observed for patients receiving chemotherapy and radiation versus radiation alone as an adjuvant to surgery (p = 0.02). CONCLUSIONS In this 10-year analysis, the authors report outcomes of surgical intervention for patients with indeterminate or gross spinal instability due to multiple myeloma and plasmacytoma of the spine with improved neurological function following surgery and low rates of instrumentation failure.

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Section: Instrumentation and Surgical Reconstructionmentioning

confidence: 96%

“…14 Many patients present with a pathological vertebral body fracture causing acute onset of localized pain at the time of diagnosis and/ or rapid neurological decline. 6,28 The indications for surgical treatment include decompression of neural elements and/or stabilizing the spinal column.…”

mentioning

confidence: 99%

Outcomes following surgical intervention for impending and gross instability caused by multiple myeloma in the spinal column

Zadnik

Goodwin

Karami

et al. 2015

SPI

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“…Controlling post-traumatic seizures (PTS) is imperative, as this can lead to worsening cerebral ischaemia via raised ICP 9. Seizures can be controlled by sedation and paralysing agents (eg, atracurium) in the short term,13 or indeed antiepileptics such as phenytoin have been shown to be effective in the prophylaxis of PTS 14.…”

Section: Central Nervous Systemmentioning

confidence: 99%

Timing of fracture fixation from an Intensive Care Unit perspective: the obstacles to early fracture fixation

Thomson

Fry²,

Jackson

2016

Postgraduate Medical Journal

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Trauma is one of the leading causes of death worldwide, with road traffic accidents being the leading cause of death in the age group of 15-29 years However, with modern advances in management and the introduction of specialised trauma centres, more and more are surviving severe and life-threatening trauma. The ideal timing of fracture fixation has been the subject of debate for a number of decades. There is evidence to suggest that fracture fixation in the patient with polytrauma is best achieved early on to reduce the incidence of morbidity and mortality, with damage control surgery in the more appropriate option in those patients who are haemodynamically unstable. However, early fracture fixation is not always possible, and the focus of this article is to review the common contributing factors resulting in delayed fixation. For the purpose of this discussion, we will consider all trauma as a single entity, taking into account that each type of fixation has its own complications, which are outside the scope of this article.

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“…Seddon's classification on peripheral nerve injury consists of neurapraxia or conduction block which has a good recovery; axonotomesis where the axon is physically disrupted but endoneurieum is intact and has a good prognosis; and neurotmesis which has complete disruption of axon and all surrounding structures and has a poor prognosis for functional recovery (Braddom, 2011). Peripheral nerve regeneration occurs approximately 1 mm a day or 1 inch a month (Greenberg, 2010). The patient's symptoms were consistent with a femoral mononeuropathy.…”

mentioning

confidence: 96%

“…Differential diagnosis can include L2-4 radiculopathy, lumbosacral plexopathy, and diabetic amyotrophy. A neuropathy can be either sensory, motor, or both (Greenberg, 2010). Nerve conduction studies and needle EMG are useful in assessing the type and severity of peripheral neuropathy.…”

mentioning

confidence: 99%

Rehabilitation Barriers Recognized in a Geriatric Patient after Cardiac Revascularization Procedure

Goodwin-Esola

Gatti²,

Chokshi

2014

Physical & Occupational Therapy In Geriatrics

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Handbook of Neurosurgery

Cited by 232 publications

References 0 publications

Outcomes following surgical intervention for impending and gross instability caused by multiple myeloma in the spinal column

Outcomes following surgical intervention for impending and gross instability caused by multiple myeloma in the spinal column

Timing of fracture fixation from an Intensive Care Unit perspective: the obstacles to early fracture fixation

Rehabilitation Barriers Recognized in a Geriatric Patient after Cardiac Revascularization Procedure

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