Hand-Held Transistor Based Electrical and Multiplexed Chemical Sensing System

Kaisti, Matti; Boeva, Zhanna A.; Koskinen, Juho; Nieminen, Sami; Bobacka, Johan; Levón, Kalle

doi:10.1021/acssensors.6b00520

Cited by 38 publications

(25 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Latch-up and noise reduction can be obtained by proper bulk/well biasing and design layout. Apart from the noise ascribable to the FET, and eventually to the signal line if not properly shielded, the EGFET sensor does not significantly suffer from other external interference due to coupling from high to low impedance, since it is physically located near where the reaction takes place [ 37 ].…”

Section: Fundamental Principles Of Egfetmentioning

confidence: 99%

EGFET-Based Sensors for Bioanalytical Applications: A Review

Pullano

Critello

Mahbub

et al. 2018

Sensors

129

View full text Add to dashboard Cite

Since the 1970s, a great deal of attention has been paid to the development of semiconductor-based biosensors because of the numerous advantages they offer, including high sensitivity, faster response time, miniaturization, and low-cost manufacturing for quick biospecific analysis with reusable features. Commercial biosensors have become highly desirable in the fields of medicine, food, and environmental monitoring as well as military applications, whereas increasing concerns about food safety and health issues have resulted in the introduction of novel legislative standards for these sensors. Numerous devices have been developed for monitoring biological processes such as nucleic acid hybridization, protein–protein interaction, antigen–antibody bonds, and substrate–enzyme reactions, just to name a few. Since the 1980s, scientific interest moved to the development of semiconductor-based devices, which also include integrated front-end electronics, such as the extended-gate field-effect transistor (EGFET) biosensor, one of the first miniaturized chemical sensors. This work is intended to be a review of the state of the art focused on the development of biosensors and chemosensors based on extended-gate field-effect transistor within the field of bioanalytical applications, which will highlight the most recent research reported in the literature. Moreover, a comparison among the diverse EGFET devices will be presented, giving particular attention to the materials and technologies.

show abstract

Section: Fundamental Principles Of Egfetmentioning

confidence: 99%

EGFET-Based Sensors for Bioanalytical Applications: A Review

Pullano

Critello

Mahbub

et al. 2018

Sensors

129

View full text Add to dashboard Cite

show abstract

“…Electrochemical sensors are considered as one of the most prominent and ideal category of sensor technology (Hrapovic et al, 2004 ; Nemiroski et al, 2014 ; Dedelaite et al, 2015 ; Baoyan et al, 2016 ; Deshmukh et al, 2017 ; Gu et al, 2018 ). Organic composite materials are widely used in electrochemical sensors due to their high catalytic activity, large surface area (Cernat et al, 2012 ; Mittal et al, 2015 ; Kaisti et al, 2016 ), ease of synthesis (Xue et al, 2014 ; Zhanna and Vladimir, 2014 ), electron transfer and modification by ample number of biochemical and chemical ligands (Oztekin et al, 2011a , 2012a ).…”

Section: Introductionmentioning

confidence: 99%

Nanocomposite Platform Based on EDTA Modified Ppy/SWNTs for the Sensing of Pb(II) Ions by Electrochemical Method

et al. 2018

View full text Add to dashboard Cite

Heavy metal ions are considered as one of the major water pollutants, revealing health hazards as well as threat to the ecosystem. Therefore, investigation of most versatile materials for the sensitive and selective detection of heavy metal ions is need of the hour. Proposed work emphasizes the synthesis of conducting polymer and carbon nanotube nanocomposite modified with chelating ligand for the detection of heavy metal ions. Carbon nanotubes are having well known features such as tuneable conductivity, low density, good charge transport ability, and current carrying capacity. Conducting polymers are the most reliable materials for sensing applications due to their environmental stability and tuning of conductivity by doping and de-doping. Formation of nanocomposite of these two idealistic materials is advantageous over the individual material, which can help to tackle the individual limitations of these materials and can form versatile materials with ideal chemical and electrical properties. Chelating ligands are the most favorable materials due to their ability of complex formation with metal ions. The present work possesses a sensing platform based on conducting polymer and carbon nanotube nanocomposite, which is stable in various aqueous media and possess good charge transfer ability. Chelating ligands played an important role in the increased selectivity toward metal ions. Moreover, in present investigation Ethylenediaminetetraacetic acid (EDTA) functionalized polypyrrole (Ppy) and single walled carbon nanotubes (SWNTs) nanocomposite was successfully synthesized by electrochemical method on stainless steel electrode (SSE). The electrochemical detection of Pb(II) ions using EDTA-Ppy/SWNTs nanocomposite was done from aqueous media. Cyclic voltammetry technique was utilized for the electrochemical synthesis of Ppy/SWNTs nanocomposite. Ppy/SWNTs nanocomposite was further modified with EDTA using dip coating technique at room temperature. The EDTA-Ppy/SWNTs modified stainless steel electrode (SSE) exhibited good sensitivity and selectivity toward heavy metal ions [Pb(II)]. Detection limit achieved for Pb(II) ions was 0.07 μM.

show abstract

“…EGFET sensor does not significantly suffer from other external interferences due to coupling from high-to-low impedance, since it is physically located near where the reaction takes place [32].…”

Section: Fet Devicementioning

confidence: 99%

EGFET Based Sensors for Bioanalytical Applications: A Review

Pullano¹,

Critello²,

Mahbub³

et al. 2018

Preprint

View full text Add to dashboard Cite

Since 1970s, a great deal of attention has been paid to the development of semiconductor–based biosensors because of the numerous advantages they offer, including high sensitivity, faster response time, miniaturization, and low–cost manufacturing for quick biospecific analysis with reusable features. Commercial biosensors have become highly desirable in the fields of medicine, food, environmental monitoring as well as military applications (e.g., Hoffmann–La Roche, Abbott Point of Care, Orion High technologies, etc.), whereas increasing concerns on the food safety and health issues have resulted in the introduction of novel legislative standards for these sensors. Numerous devices have been developed for monitoring of biological–processes such as nucleic–acid hybridization, protein–protein interaction, antigen–antibody bonds and substrate–enzyme reactions, just to name a few. Since 1980s scientific interest moved to the development of semiconductor–based devices which also include integrated front–end electronics, such as the extended–gate–field–effect–transistor biosensor which is one of the first miniaturized chemical sensors. This work is intended to be a review of the state of the art focused on the development of biosensors based extended–gate–field–effect–transistor within the field of bioanalytical applications, which will highlight the most recent research works reported in the literature. Moreover, a comparison among the diverse EGFET devices will be presented giving particular attention to the materials and technologies.

show abstract

Hand-Held Transistor Based Electrical and Multiplexed Chemical Sensing System

Cited by 38 publications

References 34 publications

EGFET-Based Sensors for Bioanalytical Applications: A Review

EGFET-Based Sensors for Bioanalytical Applications: A Review

Nanocomposite Platform Based on EDTA Modified Ppy/SWNTs for the Sensing of Pb(II) Ions by Electrochemical Method

EGFET Based Sensors for Bioanalytical Applications: A Review

Contact Info

Product

Resources

About