Hand and Foot Moisturizers

Weber, Teresa; Schoelermann, Andrea M.; Breitenbach, Ute; Scherdin, U.; Kowcz, Alexandra

doi:10.1002/9781118655566.ch15

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Barrier Restoring Therapies Moisturizers2

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2016

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Cited by 1 publication

(2 citation statements)

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“…or endogenous factors (e.g., aging, deficiencies in the skin's natural moisturizing factor (NMF), barrier lipid content, etc.) [67][68][69]. Moisturizers are widely applied to treat dry skin caused by different factors and are based on several formulations which contribute to barrier repair, reduction of TEWL or aesthetic improvement of irritated skin [67].…”

Section: Barrier Restoring Therapies Moisturizersmentioning

confidence: 99%

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Pharmacological Targeting of the Epidermal Barrier

Kemény¹,

Nagy²,

Csoma³

et al. 2016

CPD

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The most important function of the skin is to form a barrier between the body and the external environment. The epidermal barrier prevents transepidermal water loss from the skin, but also serves as a barrier to the entry of harmful environmental allergic, toxic or infectious substances. Inherited defects in the genes encoding the components of the epidermal barrier result in the development of rare genetic disorders, whereas polymorphisms in these genes together with environmental factors cause frequent inflammatory skin diseases, such as atopic dermatitis. In this review, components of the skin-barrier function will be reviewed with special emphasis on how the altered epidermal barrier might be repaired. The different strategies to increase the transdermal penetration of drugs is also discussed.3

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Section: Barrier Restoring Therapies Moisturizersmentioning

confidence: 99%

“…Silicones (e.g., dimethicone, cyclomethicone) are relatively new hypoallergenic occlusives. A disadvantage of occlusive preparations is that they can be aesthetically less pleasing than oilin-water emulsions [67,68,71].…”

Section: Barrier Restoring Therapies Moisturizersmentioning

confidence: 99%