Hamartoma mamario

Ruíz-Tóvar, Jaime; Reguero-Callejas, María Eugenia; Arano-Bermejo, Juan Ignacio; González-Palacios, Fernando; Cabañas-Navarro, Luis

doi:10.1016/s0009-739x(06)70848-x

Cited by 7 publications

(8 citation statements)

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“…In total, 27 hamartomas (3.1%) were diagnosed among 864 benign breast tumors at our center over the last ten years. In the literature (23,28,29,31,33,34,37), the average age of the patients with breast hamartoma ranged between 33.5 and 66.5 years. In our study, the age range was from 19-56 years and the mean age was 41.8 years.…”

Section: Discussionmentioning

confidence: 99%

Breast hamartoma: a clinicopathologic analysis of 27 cases and a literature review

Sevim¹,

Kocaay²,

Eker³

et al. 2014

Clinics

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OBJECTIVES:Breast hamartoma is an uncommon breast tumor that accounts for approximately 4.8% of all benign breast masses. The pathogenesis is still poorly understood and breast hamartoma is not a well-known disorder, so its diagnosis is underestimated by clinicians and pathologists. This study was designed to present our experience with breast hamartoma, along with a literature review.METHOD:We reviewed the demographic data, pathologic analyses and imaging and results of patients diagnosed with breast hamartoma between December 2003 and September 2013.RESULTS:In total, 27 cases of breast hamartoma operated in the Ankara University Medicine Faculty's Department of General Surgery were included in the study. All patients were female and the mean age was 41.8±10.8 years. The mean tumor size was 3.9±2.7 cm. Breast ultrasound was performed on all patients before surgery. The most common additional lesion was epithelial hyperplasia (22.2%). Furthermore, lobular carcinoma in situ was identified in one case and invasive ductal carcinoma was observed in another case. Immunohistochemical staining revealed myoid hamartoma in one case (3.7%).CONCLUSION:Breast hamartomas are rare benign lesions that may be underdiagnosed because of the categorization of hamartomas as fibroadenomas by pathologists. Pathologic examinations can show variability from one case to another. Thus, the true incidence may be higher than the literature indicates.

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Section: Discussionmentioning

confidence: 99%

Breast hamartoma: a clinicopathologic analysis of 27 cases and a literature review

Sevim¹,

Kocaay²,

Eker³

et al. 2014

Clinics

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“…These tumors have smooth contours, and may include fat, fibrous and glandular tissue in various amounts. More than 60% of these are soft and cannot be palpated (5). As their contents vary, mammography findings show differences.…”

Section: Introductionmentioning

confidence: 99%

Surgical Approach to Breast Hamartoma and the Diagnostic Accuracy in Preoperative Biopsies

Tatar¹,

Erözgen²,

Tüzün³

et al. 2013

J Breasth Health

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Objective: Breast hamartomas are benign breast tumors, which are observed very rarely. We aimed to share our surgical approaches and a comparison of preoperative and postoperative pathology results of patients applying to breast polyclinics. Materials and Methods:Out of 32.000 patients approximately, we reviewed data of 12 patients with the diagnosis of breast hamartoma retrospectively, who had applied to the breast polyclinic between dates of March 2007 and October 2012.Results: All patients were female and their average age was 35 (17-58 years). Four of the hamartomas were detected in the right breast, and eight in the left breast. The average diameter of lesions was 7.3 cm (3-21cm). The diameter in our three cases was above 10 cm, and they were evaluated as giant hamartomas. All our cases underwent a fine needle aspiration biopsy (FNAB) or a core biopsy preoperatively. When the reports of preoperative biopsies performed on patients who had applied due to a palpable mass and the postoperative pathology reports were compared, it was detected that they showed a substantial correlation. Conclusion:Hamartomas are benign tumors of the breast. The rate of preoperative diagnosis is high when physical examination, imaging and histopathology approaches are taken in combination. Although very rare, a surgical excision should be performed due to the malignant change in tumors. Hamartomların dördü sağ memede sekizi sol memede saptandı. Lezyonların ortalama çapı 7,3 cm idi (min-maks; 3-21). Üç olguda lezyon çapı 10 cm üzerinde olup bu olgular dev hamartom olarak değerlendirildi. Olgularımı-zın hepsine preoperatif ince iğne aspirasyon biyopsisi (İİAB) veya kor biyopsi yapıldı. Ele gelen kitle ile başvuran hastalara yapılan preoperatif biyopsi ile postoperatif patoloji raporları karşılaştırıldığında büyük oranda korelasyon gösterdikleri tespit edildi.Sonuç: Hamartomlar memenin iyi huylu tümörleridir. Fizik muayene, gö-rüntüleme ve histopatolojinin birlikte ele alınmasıyla preoperatif tanı konma oranı yüksektir. Çok nadir de olsa malign değişim göstermesi sebebiyle cerrahi eksizyon yapılmalıdır.

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“…This pathological entity has a reported incidence of 1.2% of benign lesions and 4-8% of benign breast tumors in women [1][2]. It appears that with the increasing use of breast screening more hamartomas are likely to be identified.…”

mentioning

confidence: 99%

“…Breast hamartomas usually present as painless mobile breast lumps in middle-aged women. Up to 60% of these benign breast lesions are soft and non-palpable [2]. …”

mentioning

confidence: 99%