Haemostatic property of cyanoacrylate in pedicled flaps

Oral Applications of Cyanoacrylate Adhesives: A Literature Review

“…In addition, the cyanoacrylate adhesive has been used in free gingival grafting [19–21], apicectomy [10], root sectioning [22], and bonding of fractured tooth fragments [23]. Kulkarni et al [24] reported the use of cyanoacrylate in periodontal pockets during surgical procedures involving periodontal flaps in 24 individuals, Ozcan et al [25] used it to promote palatal wound healing after free gingival graft harvesting, and Ranson et al [26] used it for stabilizing pedicle grafts during soft tissue surgeries.…”

Composition, host responses and clinical applications of bioadhesives

“…They are formulated with synthetic polymers as a backbone functionalized with reactive groups and are crosslinked or coated via a non‐natural cross‐linker. The most common synthetic bioadhesives include polyurethane‐, polyethylene glycol (PEG)‐ and cyanoacrylate‐based formulations. Cyanoacrylate‐based adhesives (e.g., Histoacryl®, 20 Dermabond®, 21 Indermil™, and Glubran 2® 22 ) have been on the market for almost four decades now. They contain alkyl‐2‐cyanoacrylate monomers, which polymerize by an exothermic reaction on exposure to nucleophilic species, such as hydroxyl groups (in the exudate), at room temperature (Figure 1A).…”

“…• Cyanoacrylate-based adhesives (e.g., Histoacryl ® , 20 Dermabond ® , 21 Indermil™, and Glubran 2 ®22 ) have been on the market for almost four decades now. They contain alkyl-2-cyanoacrylate monomers, which polymerize by an exothermic reaction on exposure to nucleophilic species, such as hydroxyl groups (in the exudate), at room temperature (Figure 1A).…”