Hæmoglobinuria and Acute Hæmolytic Anæmia Associated With Primary Atypical Pneumonia

Idiopathic non-syphilitic paroxysmal cold haemoglobinuria in children.

“…We wonder if these were true DL antibodies. It is possible that, in some cases, cold autoagglutinins such as anti-I or anti-i may have been present in addition to a DL antibody, for example, the cases of Stewart and Friedlander (1957), Bell et al (1973), Wishart and Davey (1973), and Djaldetti et al (1975).…”

“…The cases of Stewart andFriedlander (1957) andBell et al (1973) were associated with primary atypical pneumonia (Mycoplasma pneumoniae infection) in which anti-I is usually present, and the case of Wishart and Davey (1973) was associated with infectious mononucleosis in which anti-i is often present. The antibodies in all three of these cases were strongly haemagglutinating.…”

Primary Atypical Pneumonia and High Sedimentation Rates

“…In this condition the very rapid rates sometimes found are related to the high concentration of y-globulin which occurs (Waldenstrom et al, 1951). MacLean and Parnell (1955) have described a case of pneumonia associated with a high titre of cold agglutinins and with a haemolytic anaemia; a similar case has been reported by Stewart and Friedlander (1957). The Westergren sedimentation rates were 158 and 156 mm.…”

A Reevaluation of the Role of Mycoplasmas in Human Disease

“…Avirulent M pneumoniae appear not to damage the cilia or epithelium. The complications and sequelae that have been correlated with M pneumoniae infection include hematologic (61,152,163), gastrointestinal (62), musculoskeletal (101,110), cardiovascular (50,82), dermatologic (73,81,119), and neurologic manifestations (92,113). However, others have shown no quantitative differences in peroxide production by virulent and avirulent strains (115).…”