Haematological and plasma biochemical values for healthy Yucatan micropigs

Abstract

SummaryBlood samples (n = 135) were collected from 36 male and 35 female 20 ± 4-week-old Yucatan micro pigs and were analysed for 19 haematological and 18 plasma biochemical parameters at weeks 20, 24, 33, 46, 59, 71 and 80. For each parameter, the total number of analyses per sex, mean values, standard deviation, lowest and highest values, and 950/0 confidence intervals are presented as reference values for this breed. Ageand sex-related differences in these parameters are also discussed.

An association between type A porcine endogenous retrovirus copy number and hematological parameters and gender in miniature pigs

“…All blood parameters were in agreement with the accepted physiological norms (Kondrakhin, 2004) and data obtained from other breeds of pigs (Rispat et al, 1993;Ekser et al, 2012;Kawaguchi et al, 2012). The white blood cell count (WBC), monocyte, basophil and eosinophil count (MID#) and gra nu locyte count (GRA#), as well as the red blood cell distribu tion width (RDWCV) were significantly higher in males than in females.…”

“…In Yucatan miniature pigs, the only detected difference between males and females was the higher platelet count in males (Rispat et al, 1993). The observed gender differences in hematological parameters between pigs of different breeds might be due to the influence of both genetic and environmental factors (feed, external conditions, etc.…”

Reference Values of Hematological and Biochemical Parameters for the World Smallest Microminipigs

“…The serum levels of alanine aminotransferase, globulin, and total cholesterol were higher in females, and those of urea nitrogen and sodium were higher in males. The major hematological and biochemical parameters in Microminipigs were similar to those in Göttingen and Yucatan minipig, although alkaline phosphatase and albumin showed higher tendency, and APTT and total bilirubin showed lower tendency [2,3,9]. These differences on the hematology and biochemistry between Microminipigs and other minipigs may be related to environmental factors such as diets or genetic factors.…”

“…Because of their physiological and anatomical similarities to humans [5], swine are becoming increasingly attractive animal models in toxicological and pharmacological research. Recently, minipigs defined that they are smaller than domestic swine and their body weight (BW) is <100 kg, have been developed including the strains of Göttingen, Yucatan, Sinclair, Clawn, and others [2,9,14]. However, most minipigs are difficult to manage due to their large size, e.g.…”

Nutritional programming of gastrointestinal tract development. Is the pig a good model for man?

“…The rapid growth and mature size of these animals could be limiting factors for the porcine model (90 -120 kg and 330 -450 kg at age 6 months and at adult stage, respectively) (80,172) . As an example, a Large White pig weighing 100 -120 kg represents an adolescent rather than an adult model ( Table 2).…”