Haematological and immunophenotypic evaluation of peripheral blood cells of cattle naturally infected with bovine papillomavirus

Therapeutic effectiveness of Ocimum basilicum extract on bovine cutaneous papillomatosis

“…The interesting in cutaneous papillomatosis that the hematological parameters of BPV-infected animals negatively changed as a significant reduction of hemoglobin, packed cell volume (PCV), and hematocrit, and produced leucopenia with lymphopenia and monocytopenia suggesting diseaseinduced stress releasing endogenous corticosteroids in response to (Palanivel et al, 2017 andEl-Mandrawy andAlam, 2018) or due to weakening of animals, off food, or anemia ( Palanivel et al, 2017 andBassi et al, 2019). A significant (P < 0.05) increase in monocytes was recorded while, PCV% and lymphocytes significantly decreased.…”

“…The antioxidant enzyme activities of erythrocyte in the papillomatosis infected-animals can be used as peripheral evidence on oxidative stress besides that erythrocytes are easy to obtain (Sasmaz et al, 2005). So, we have chosen erythrocyte (Palanivel et al, 2017 andBassi et al, 2019) to estimate the antioxidant enzyme activities in BPV-patients with cutaneous papillomatosis. A significant decreased MDA (lipid peroxidation) and a significant increase in GSH-Px were observed while changes in SOD and GSH activities were insignificant.…”

“…Therapeutic effectiveness of the extract was clinicopathologically assessed. Hematobiochemical parameters (Palanivel et al, 2017 andBassi et al, 2019) in addition to the oxidative stress biomarkers were assessed in the blood of infected animals to screen any change in diseaseassociated body condition and if there is any adverse effect could occur. Infected animals were diagnosed by clinical and histopathological methods.…”

Current methods and prospects of coronavirus detection

“… [ 53 ] Papillomaviruses The CD8 + T cells of natural killer cells, IFN-γ and IL-17 are increased, on the contrary, the ratio of γδ+ T cells and CD4+/CD8+ is decreased. [ 54 ] …”

“…Therefore, this method also needs further optimization. [ 2 , 54 ] PCR PCR is a highly sensitive and sequence specific enzyme method. This method is widely used in virus detection and has been widely accepted by researchers.…”