Haemato-biochemical studies of Theileria orientalis infection in cross bred dairy cattle

Abstract

The present work has been carried out to study the haemato-biochemical profiles of cattle infected with oriental theileriosis. Theileriosis was diagnosed in 30 cross bred cattle by blood smear examination and confirmed by PCR. Whole blood samples were collected from positive animals and were subjected to estimation of haemato-biochemical parameters. Haematological analysis revealed significant decrease in total erythrocyte count (TEC), haemoglobin, volume of packed red cells (VPRC) and granulocyte count, significant increase in total leucocyte count (TLC), lymphocyte count, monocyte count and granulocyte count in T. orientalis infected animals. Non-significant changes were noticed in mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH) and mean corpuscular haemoglobin concentration (MCHC). Biochemical analysis revealed significant decrease in albumin concentration and significant increase in blood urea nitrogen level in T. orientalis infected animals. The knowledge on alterations in haemato-biochemical profiles of affected animals will help to assess the severity of infection and to make a tentative diagnosis of the condition.

Assessment of oxidative stress and antioxidant status in cattle infected with Theileria orientalis

“…The haematological parameters (Table 2) showed a statistically significant reduction in the mean values of TEC, haemoglobin and VPRC in T. orientalis infected animals compared with animals of control group. Similar findings were also reported by Izzo et al (2010), Aparna et al (2011), Jackson (2018) and Goud et al (2021). This reduction in TEC, haemoglobin and VPRC could be due to the development of anaemia in these animals.…”

Buparvakuon

“…Successful treatment of Theileriosis in cattle and calves has been reported using buparvaquone, meloxicam, vitamins (A, E, D3, Biotin), and flumethrin applications (20). It has been reported that buparvaquone and oxytetracycline treatment was effective in cattle infected with Theileria orientalis, but complete elimination was not achieved (21). It was stated that a one-month-old Kankrej breed cattle calf did not suckle milk, was stagnant, and had fever, and Theileriosis was diagnosed by blood examination.…”