Gynaecological cancer in pregnancy

Ilancheran, A.; Low, Jeffrey; Ng, Joseph

doi:10.1016/j.bpobgyn.2011.12.009

Cited by 15 publications

(25 citation statements)

References 22 publications

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“…Undoubtedly, it is the most common cancer in pregnancy among all gynaecological malignant growths [3–5]. …”

Section: Cervical Cancer During Pregnancymentioning

confidence: 99%

“…Pregnancy does not have a negative impact on prognosis and the therapeutic outcomes are the same as in non-pregnant women [3, 5]. …”

Section: Cervical Cancer During Pregnancymentioning

confidence: 99%

“…If there is no evidence of invasion, no treatment should be implemented during pregnancy and the entire therapy can be postponed until after the birth. In patients with no invasive changes, monitoring is recommended using colposcopy performed in each trimester with repeated biopsy in cases suspected of progression [3, 5]. …”

Section: Cervical Cancer During Pregnancymentioning

confidence: 99%

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Gynaecological cancers coexisting with pregnancy – a literature review

Skrzypczyk-Ostaszewicz

Rubach

2016

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The coexistence of malignant tumour and pregnancy is a state of simultaneous occurrence of two completely contradictory philosophical and biological phenomena – the development of a new life and a life-threatening terminal illness. Finally, a physician – in fact the whole team of doctors – is facing the fight for two lives: of the mother and her unborn child.The incidence of malignant disease in pregnancy is 0.05 to 0.1%. This condition is a major challenge for physicians because there are no randomised studies that could be the basis to choose the therapeutic methods – the medical knowledge merely comes from case reports, registries, and observational studies.The following cancers most often coexist with pregnancy: gynaecological neoplasm (especially cervical and ovarian cancer), breast cancer, lymphatic system neoplasm, and melanoma.Formerly, the diagnosis was clearly the necessity of abortion. Today – although unskilled doctors still propose the only therapeutic option – termination of pregnancy is not the only solution.The past few years have seen the updating of reports and guidelines for the management of pregnant women with cancer. This paper is a review and summary of the information from these publications.

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“…Undoubtedly, it is the most common cancer in pregnancy among all gynaecological malignant growths [3–5]. …”

Section: Cervical Cancer During Pregnancymentioning

confidence: 99%

“…Pregnancy does not have a negative impact on prognosis and the therapeutic outcomes are the same as in non-pregnant women [3, 5]. …”

Section: Cervical Cancer During Pregnancymentioning

confidence: 99%

Section: Cervical Cancer During Pregnancymentioning

confidence: 99%

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Gynaecological cancers coexisting with pregnancy – a literature review

Skrzypczyk-Ostaszewicz

Rubach

2016

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“…If pregnancy preservation is desired, the tretament choices can depend on before diagnosed 20-22 weeks or after. For pregnant women with early stage disease (FIGO: IA2, IB1, 2A) diagnosed after 20 weeks of gestation, treatment may be delayed until the fetus has gain maturity [1,4]. An individualized treatment plan should be determined, regarding fetal maturity, however, delaying treatment beyond 32-34 weeks is not recommended.…”

Section: Discussonmentioning

confidence: 99%

“…The diagnostic approach to cervical cancer during pregnancy is similar to that of nonpregnant women. Cervical cancer is staged clinically by clinical examination, in pregnant women, especially after the second trimester and beyond, clinical examination can be difficult [1,4]. Also, during pregnancy physiological cervical changes at cervical tissue such as oedem, increased vascularity, and hypertrophy may change tumor size, as well as stage.…”

Section: Discussonmentioning

confidence: 99%

Cesarean Delivery with Bilateral Ovarian Transposition for Locally Advanced Cervical Cancer

Alanbay¹,

Öztürk²,

Ulubay³

et al. 2016

Ann Clin Anal Med

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ÖzetBiz vakamızda özellikle 3. trimestırda lokal ileri evre serviks kanserinin, sezeryan ile doğum esnasında ovaryan transpozisyon uygulama yöntemi hakkında tartışma-yı amaçladık. Hastamız 26 yaşında gebeliğinin 29 haftasında olup 9 gündür amnios sızıntısı devam etmektedir. Steril spekulum incelemesi sırasında geniş servikal lezyon saptandı. Servikal Biyopsi sonucu invaziv servikal kanser olarak rapor edildi. Manyetik rezonans görüntülemede şüpheli sağ parametriyal katılımı ile nodal tutulumu olmayan (MRG) 55X 63X 68 mm servikal lezyon, tutulum gösterilmiş-tir. Non-reaktif fetal durum ve şüpheli koryoamnionit ön tanısı ile elektif sezeryan planlandı. Otuzuncu gebelik haftasında elektif sezeryan ve bilateral ovaryan transpozisyon uygulandı. Pelvik radyasyon, eksternal brakiterapi ileri evre serviks kanseri için standart tedavi olarak uygulandı. Genç kadınlarda gebeliğin 3. trimestı-rında fetal matürite sağlandığında sezeryan uygulamasına ilave ovaryan transpozisyon uygulanması önerilmelidir. Anahtar KelimelerServikal Kanser; Ovaryan Transpozisyon; Gebelik AbstractWe aimed to discuss about management of pregnancy with locally advanced cervical cancer, especially at the third trimester with ovarian transposition concomittant with cesarean delivery.A 26 year old patient who was at the 29th week of gestation had amniotic leakage for 9 days. During the sterile speculum examination, a large cervical lesion was detected.The cervical biopsy revealed invasive squamous cervical cancer. An magnetic resonance imaging(MRI) showed 55X63X-68mm cervical lesion with suspicious right parametrial involvement, and no nodal involvement.An elective cesarean delivery decision was taken due to non-reassuring fetal status and suspicious chorioamnionitis.At 30th week of gestation, an elective cesarean delivery with bilateral ovarian transposition was performed.Pelvic radiation, including external beam and brachytherapy, has been the standard treatment of advanced cervical cancer.During the third trimester, fetal maturity is awaited and a caesarean section followed by standard treatment is proposed and the ovaries can be preserved with ovarian transposition in young women.

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